Publications by authors named "Rayhane Nchioua"

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HIV-2 evades restriction by ZAP through adaptations in the U3 LTR region despite increased CpG levels.
Dorota Kmiec, Rayhane Nchioua, Alexander Gabel, Asimenia Vlachou, Sabina Ganskih

Nucleic Acids Res· August 2025

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Trypstatin as a Novel TMPRSS2 Inhibitor with Broad-Spectrum Efficacy against Corona and Influenza Viruses.
Jan Lawrenz, Lukas Wettstein, Armando Rodríguez Alfonso, Rayhane Nchioua, Pascal von Maltitz

Adv Sci (Weinh)· July 2025

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Mutation T9I in Envelope confers autophagy resistance to SARS-CoV-2 Omicron.
Susanne Klute, Rayhane Nchioua, Arne Cordsmeier, Jyoti Vishwakarma, Lennart Koepke

iScience· July 2025

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Role of N-linked glycosylation sites in human ACE2 in SARS-CoV-2 and hCoV-NL63 infection.
Sabrina Noettger, Fabian Zech, Rayhane Nchioua, Chiara Pastorio, Christoph Jung

J Virol· May 2025

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Host ZAP activity correlates with the levels of CpG suppression in primate lentiviruses.
Rayhane Nchioua, Dorota Kmiec, Veronika Krchlikova, Sarah Mattes, Sabrina Noettger

Proc Natl Acad Sci U S A· April 2025

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A Gaussia luciferase reporter assay for the evaluation of coronavirus Nsp5/3CLpro activity.
Asimenia Vlachou, Rayhane Nchioua, Kerstin Regensburger, Frank Kirchhoff, Dorota Kmiec

Sci Rep· September 2024

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Attenuated replication and damaging effects of SARS-CoV-2 Omicron variants in an intestinal epithelial barrier model.
Meta Volcic, Rayhane Nchioua, Chiara Pastorio, Fabian Zech, Isabell Haußmann

J Med Virol· July 2024

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Impact of mutations defining SARS-CoV-2 Omicron subvariants BA.2.12.1 and BA.4/5 on Spike function and neutralization.
Chiara Pastorio, Sabrina Noettger, Rayhane Nchioua, Fabian Zech, Konstantin M J Sparrer

iScience· November 2023

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Tetherin Restricts SARS-CoV-2 despite the Presence of Multiple Viral Antagonists.
Elena Hagelauer, Rishikesh Lotke, Dorota Kmiec, Dan Hu, Mirjam Hohner, Rayhane Nchioua

Viruses· November 2023

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Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
Elise G Viox, Timothy N Hoang, Amit A Upadhyay, Rayhane Nchioua, Maximilian Hirschenberger

Sci Immunol· July 2023

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Reduced replication but increased interferon resistance of SARS-CoV-2 Omicron BA.1.
Rayhane Nchioua, Annika Schundner, Susanne Klute, Lennart Koepke, Maximilian Hirschenberger

Life Sci Alliance· June 2023

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Endogenous IFITMs boost SARS-coronavirus 1 and 2 replication whereas overexpression inhibits infection by relocalizing ACE2.
Qinya Xie, Caterina Prelli Bozzo, Laura Eiben, Sabrina Noettger, Dorota Kmiec, Rayhane Nchioua

iScience· April 2023

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Strong attenuation of SARS-CoV-2 Omicron BA.1 and increased replication of the BA.5 subvariant in human cardiomyocytes.
Rayhane Nchioua, Federica Diofano, Sabrina Noettger, Pascal von Maltitz, Steffen Stenger

Signal Transduct Target Ther· December 2022

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Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
Timothy N Hoang, Elise G Viox, Amit A Upadhyay, Zachary Strongin, Gregory K Tharp, Rayhane Nchioua

bioRxiv· October 2022

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Actin cytoskeleton remodeling primes RIG-I-like receptor activation.
Dhiraj Acharya, Rebecca Reis, Meta Volcic, GuanQun Liu, May K Wang, Rayhane Nchioua

Cell· September 2022

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SARS-CoV-2 Variants of Concern Hijack IFITM2 for Efficient Replication in Human Lung Cells.
Rayhane Nchioua, Annika Schundner, Dorota Kmiec, Caterina Prelli Bozzo, Fabian Zech

J Virol· June 2022

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Serially passaged, conditionally reprogrammed nasal epithelial cells as a model to study epithelial functions and SARS-CoV-2 infection.
Hanna Schmidt, Lara Guthjahr, Alexander Sauter, Fabian Zech, Rayhane Nchioua

Am J Physiol Cell Physiol· April 2022

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Spike residue 403 affects binding of coronavirus spikes to human ACE2.
Fabian Zech, Daniel Schniertshauer, Christoph Jung, Alexandra Herrmann, Arne Cordsmeier, Rayhane Nchioua

Nat Commun· November 2021

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SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3.
Utkarsh Tripathi, Rayhane Nchioua, Larissa G P Langhi Prata, Yi Zhu, Erin O Wissler Gerdes

Aging (Albany NY)· September 2021

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APOBEC3F Constitutes a Barrier to Successful Cross-Species Transmission of Simian Immunodeficiency Virus SIVsmm to Humans.
Rayhane Nchioua, Dorota Kmiec, Amit Gaba, Christina M Stürzel, Tyson Follack

J Virol· August 2021

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IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro.
Caterina Prelli Bozzo, Rayhane Nchioua, Meta Volcic, Lennart Koepke, Jana Krüger

Nat Commun· July 2021

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Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities.
Manuel Hayn, Maximilian Hirschenberger, Lennart Koepke, Rayhane Nchioua, Jan Hendrik Straub

Cell Rep· May 2021

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SARS-CoV-2 Is Restricted by Zinc Finger Antiviral Protein despite Preadaptation to the Low-CpG Environment in Humans.
Rayhane Nchioua, Dorota Kmiec, Janis A Müller, Carina Conzelmann, Rüdiger Groß

mBio· October 2020

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Cellular Factors Targeting HIV-1 Transcription and Viral RNA Transcripts.
Rayhane Nchioua, Matteo Bosso, Dorota Kmiec, Frank Kirchhoff

Viruses· April 2020

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CpG Frequency in the 5' Third of the Gene Determines Sensitivity of Primary HIV-1 Strains to the Zinc-Finger Antiviral Protein.
Dorota Kmiec, Rayhane Nchioua, Scott Sherrill-Mix, Christina M Stürzel, Elena Heusinger

mBio· January 2020

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