Publications by authors named "Amit A Upadhyay"

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Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
Timothy N Hoang, Maria Pino, Arun K Boddapati, Elise G Viox, Carly E Starke, Amit A Upadhyay, Sanjeev Gumber, Michael Nekorchuk, Kathleen Busman-Sahay, Zachary Strongin

January 2021

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Primate resident memory T cells activate humoral and stromal immunity.
Vineet Joag, Benjamin N Bimber, Clare F Quarnstrom, Venkata S Bollimpelli, Jason M Schenkel, Amit A Upadhyay

Immunity· October 2025

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Diverse priming outcomes under conditions of very rare precursor B cells.
Patrick J Madden, Ester Marina-Zárate, Kristen A Rodrigues, Jon M Steichen, Monolina Shil, Amit A Upadhyay

Immunity· April 2025

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A Broad Survey and Functional Analysis of Immunoglobulin Loci Variation in Rhesus Macaques.
Ayelet Peres, Amit A Upadhyay, Vered Hana Klein, Swati Saha, Oscar L Rodriguez

bioRxiv· March 2025

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Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques.
Christopher T Edwards, Kirti A Karunakaran, Elijah Garcia, Nathan Beutler, Matthew Gagne, Amit A Upadhyay

PLoS Pathog· January 2025

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Diverse priming outcomes under conditions of very rare precursor B cells.
Patrick J Madden, Ester Marina-Zárate, Kristen A Rodrigues, Jon M Steichen, Monolina Shil, Amit A Upadhyay

bioRxiv· November 2024

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Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques.
Christopher T Edwards, Kirti A Karunakaran, Elijah Garcia, Nathan Beutler, Matthew Gagne, Amit A Upadhyay

bioRxiv· July 2024

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Natural killer-like B cells are a distinct but infrequent innate immune cell subset modulated by SIV infection of rhesus macaques.
Cordelia Manickam, Amit A Upadhyay, Griffin Woolley, Kyle W Kroll, Karen Terry

PLoS Pathog· May 2024

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Frequency-potency analysis of IgG+ memory B cells delineates neutralizing antibody responses at single-cell resolution.
Michelle K Tenggara, Seo-Ho Oh, Catherine Yang, Hardik K Nariya, Amanda M Metz, Amit A Upadhyay

Cell Rep· March 2024

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High throughput analysis of B cell dynamics and neutralizing antibody development during immunization with a novel clade C HIV-1 envelope.
Rohini Mopuri, Sarah Welbourn, Tysheena Charles, Pooja Ralli-Jain, David Rosales, Amit A Upadhyay

PLoS Pathog· October 2023

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Intradermal but not intramuscular modified vaccinia Ankara immunizations protect against intravaginal tier2 simian-human immunodeficiency virus challenges in female macaques.
Venkata S Bollimpelli, Pradeep B J Reddy, Sailaja Gangadhara, Tysheena P Charles, Samantha L Burton, Amit A Upadhyay

Nat Commun· August 2023

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Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
Elise G Viox, Timothy N Hoang, Amit A Upadhyay, Rayhane Nchioua, Maximilian Hirschenberger

Sci Immunol· July 2023

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TREM2 and interstitial-like macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques.
Amit A Upadhyay, Elise G Viox, Timothy N Hoang, Arun K Boddapati, Maria Pino

Nat Commun· April 2023

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Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
Timothy N Hoang, Elise G Viox, Amit A Upadhyay, Zachary Strongin, Gregory K Tharp

bioRxiv· October 2022

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A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence.
Sarah Welbourn, Srirupa Chakraborty, Jie E Yang, Anne S Gleinich, Sailaja Gangadhara, Amit A Upadhyay

PLoS Pathog· May 2022

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Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates.
Jacqueline Corry, Gwenddolen Kettenburg, Amit A Upadhyay, Megan Wallace, Michelle M Marti

PLoS Pathog· March 2022

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From structure to sequence: Antibody discovery using cryoEM.
Aleksandar Antanasijevic, Charles A Bowman, Robert N Kirchdoerfer, Christopher A Cottrell, Gabriel Ozorowski, Amit A Upadhyay

Sci Adv· January 2022

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TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques.
Amit A Upadhyay, Timothy N Hoang, Maria Pino, Arun K Boddapati, Elise G Viox

bioRxiv· October 2021

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Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection.
Michelle Y-H Lee, Amit A Upadhyay, Hasse Walum, Chi N Chan, Reem A Dawoud

PLoS Pathog· June 2021

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IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques.
Justin Harper, Nicolas Huot, Luca Micci, Gregory Tharp, Colin King, Amit A Upadhyay

Nat Commun· May 2021

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A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs.
Nanda Kishore Routhu, Narayanaiah Cheedarla, Sailaja Gangadhara, Venkata Satish Bollimpelli, Arun K Boddapati, Amit A Upadhyay

Immunity· March 2021

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Clinical and whole genome characterization of SARS-CoV-2 in India.
Radhakrishna Muttineni, Nagamani Kammili, Thrilok Chander Bingi, Raja Rao M, Kalyani Putty, Amit A Upadhyay

PLoS One· February 2021

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Early T follicular helper cell activity accelerates hepatitis C virus-specific B cell expansion.
Eduardo Salinas, Maude Boisvert, Amit A Upadhyay, Nathalie Bédard, Sydney A Nelson

J Clin Invest· January 2021

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Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans.
Prabhu S Arunachalam, Florian Wimmers, Chris Ka Pun Mok, Ranawaka A P M Perera, Madeleine Scott, Amit A Upadhyay

Science· September 2020

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Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
Timothy N Hoang, Maria Pino, Arun K Boddapati, Elise G Viox, Carly E Starke, Amit A Upadhyay

bioRxiv· September 2020

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