Publications by authors named "Reiner Class"

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Considerations from the pharmaceutical industry (IQ MPS Affiliate) workshop on animal microphysiological systems and 3Rs in drug development.
Patrick J Devine, Manti Guha, Jason E Ekert, Anna K Kopec, James R Gosset, Reiner Class

ALTEX· July 2025

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Assessing the interplay between off-target promiscuity, cytotoxicity, and tolerability in rodents to improve the safety profile of novel anti-malarial plasmepsin X inhibitors.
Helga H J Gerets, Annie Delaunois, Alvaro Cardenas, Reiner Class, Renaud Fleurance

Toxicol Sci· October 2024

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A Perfused In Vitro Human iPSC-Derived Blood-Brain Barrier Faithfully Mimics Transferrin Receptor-Mediated Transcytosis of Therapeutic Antibodies.
Floriana Burgio, Carine Gaiser, Kevin Brady, Viviana Gatta, Reiner Class

Cell Mol Neurobiol· November 2023

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Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of .
Martin A Lowe, Alvaro Cardenas, Jean-Pierre Valentin, Zhaoning Zhu, Jan Abendroth, Reiner Class

J Med Chem· October 2022

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Setup of human liver-chips integrating 3D models, microwells and a standardized microfluidic platform as proof-of-concept study to support drug evaluation.
Benoit Cox, Patrick Barton, Reiner Class, Hannah Coxhead, Claude Delatour

Biomater Biosyst· August 2022

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The Promise of AI for DILI Prediction.
Andreu Vall, Yogesh Sabnis, Jiye Shi, Reiner Class, Sepp Hochreiter

Front Artif Intell· April 2021

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Cardiotoxicity testing using pluripotent stem cell-derived human cardiomyocytes and state-of-the-art bioanalytics: a review.
Carl-Fredrik Mandenius, Daniella Steel, Fozia Noor, Thomas Meyer, Elmar Heinzle, Reiner Class

J Appl Toxicol· April 2011

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Cytokine mediated proliferation of cultured sea turtle blood cells: morphologic and functional comparison to human blood cells.
Doris A Morgan, Reiner Class, Gary Violetta, Gerald Soslau

Tissue Cell· August 2009

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Inhibition of gamma-thrombin-induced human platelet aggregation by histone H1subtypes and H1.3 fragments.
Gerald Soslau, Phillip J Prest, Reiner Class, Monika Jost, Lynn Mathews

Platelets· August 2009

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Comparison of sea turtle thrombocyte aggregation to human platelet aggregation in whole blood.
Gerald Soslau, Phillip J Prest, Reiner Class, Robert George, Frank Paladino

Comp Biochem Physiol B Biochem Mol Biol· November 2005

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ICOS-B7 homologous protein interactions are necessary for mercury-induced autoimmunity.
Yan Zheng, Monika Jost, John P Gaughan, Reiner Class, Anthony J Coyle

J Immunol· March 2005

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Differential activation and inhibition of human platelet thrombin receptors by structurally distinct alpha-, beta- and gamma-thrombin.
Gerald Soslau, Seth J Goldenberg, Reiner Class, Bradford Jameson

Platelets· May 2004

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Radiation enhancement by gemcitabine-mediated cell cycle modulations.
Stephan Mose, Reiner Class, Hans-Walter Weber, Angelika Rahn, Luther W Brady

Am J Clin Oncol· February 2003

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Radioiodinated (I-125) monoclonal antibody 425 in the treatment of high grade glioma patients: ten-year synopsis of a novel treatment.
Jacqueline G Emrich, Luther W Brady, Tony S Quang, Reiner Class, Curtis Miyamoto

Am J Clin Oncol· December 2002

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[Combined radiotherapy and gemcitabine. Evaluation of clinical data based on experimental knowledge].
Stephan Mose, Reiner Class, Hans-Walter Weber, Agi Oszvald, Angelika Rahn

Strahlenther Onkol· February 2002

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