Publications by authors named "Remco Derr"

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Interlaboratory validation of the ToxTracker assay: An in vitro reporter assay for mechanistic genotoxicity assessment.
Giel Hendriks, Els Adriaens, Ashley Allemang, Julie Clements, Gabrielle Cole, Remco Derr

Environ Mol Mutagen· April 2024

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Quantitative interpretation of ToxTracker dose-response data for potency comparisons and mode-of-action determination.
Lorrie Boisvert, Remco Derr, Torben Osterlund, Giel Hendriks, Inger Brandsma

Environ Mol Mutagen· February 2023

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Genotoxicity assessment of potentially mutagenic nucleoside analogues using ToxTracker®.
Inger Brandsma, Remco Derr, Gaonan Zhang, Nynke Moelijker, Giel Hendriks

Toxicol Lett· June 2022

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A tiered approach to investigate the inhalation toxicity of cobalt substances. Tier 2 b: Reactive cobalt substances induce oxidative stress in ToxTracker and activate hypoxia target genes.
Remco Derr, Nynke Moelijker, Giel Hendriks, Inger Brandsma

Regul Toxicol Pharmacol· March 2022

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TubulinTracker, a Novel In Vitro Reporter Assay to Study Intracellular Microtubule Dynamics, Cell Cycle Progression, and Aneugenicity.
Marit E Geijer, Nynke Moelijker, Gaonan Zhang, Remco Derr, Torben Osterlund

Toxicol Sci· March 2022

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Toxicity of stainless and mild steel particles generated from gas-metal arc welding in primary human small airway epithelial cells.
Andrea Cediel-Ulloa, Christina Isaxon, Axel Eriksson, Daniel Primetzhofer, Mauricio A Sortica, Remco Derr

Sci Rep· November 2021

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The in vitro ToxTracker and Aneugen Clastogen Evaluation extension assay as a tool in the assessment of relative genotoxic potential of e-liquids and their aerosols.
Lukasz Czekala, Fiona Chapman, Liam Simms, Kathryn Rudd, Edgar Trelles Sticken, Remco Derr

Mutagenesis· May 2021

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Mode of action assessment of the genotoxic properties of antimony and its compounds evaluated in the ToxTracker assay.
Craig J Boreiko, Giel Hendriks, Remco Derr, Marjorie Huppert, Toby G Rossman

Mutat Res Genet Toxicol Environ Mutagen· May 2021

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Aneugen Versus Clastogen Evaluation and Oxidative Stress-Related Mode-of-Action Assessment of Genotoxic Compounds Using the ToxTracker Reporter Assay.
Inger Brandsma, Nynke Moelijker, Remco Derr, Giel Hendriks

Toxicol Sci· September 2020

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A Case Study with Triazole Fungicides to Explore Practical Application of Next-Generation Hazard Assessment Methods for Human Health.
Leo T M van der Ven, Emiel Rorije, R Corinne Sprong, Daniele Zink, Remco Derr

Chem Res Toxicol· March 2020

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ToxTracker Reporter Cell Lines as a Tool for Mechanism-Based (geno)Toxicity Screening of Nanoparticles-Metals, Oxides and Quantum Dots.
Sarah McCarrick, Francesca Cappellini, Amanda Kessler, Nynke Moelijker, Remco Derr

Nanomaterials (Basel)· January 2020

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The mechanism-based toxicity screening of particles with use in the food and nutrition sector via the ToxTracker reporter system.
David M Brown, Pernille Høgh Danielsen, Remco Derr, Nynke Moelijker, Paul Fowler

Toxicol In Vitro· December 2019

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High variability in toxicity of welding fume nanoparticles from stainless steel in lung cells and reporter cell lines: the role of particle reactivity and solubility.
Sarah McCarrick, Zheng Wei, Nynke Moelijker, Remco Derr, Kjell-Arne Persson

Nanotoxicology· December 2019

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Mechanistic insight into reactivity and (geno)toxicity of well-characterized nanoparticles of cobalt metal and oxides.
Francesca Cappellini, Yolanda Hedberg, Sarah McCarrick, Jonas Hedberg, Remco Derr

Nanotoxicology· August 2018

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Genotoxic and mutagenic properties of Ni and NiO nanoparticles investigated by comet assay, γ-H2AX staining, Hprt mutation assay and ToxTracker reporter cell lines.
Emma Åkerlund, Francesca Cappellini, Sebastiano Di Bucchianico, Shafiqul Islam, Sara Skoglund, Remco Derr

Environ Mol Mutagen· April 2018

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Combined evaluation of the FAS cell surface death receptor and CD8+ tumor infiltrating lymphocytes as a prognostic biomarker in breast cancer.
Erik J Blok, Jitske van den Bulk, N Geeske Dekker-Ensink, Remco Derr, Corné Kanters

Oncotarget· February 2017

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The Vitotox and ToxTracker assays: A two-test combination for quick and reliable assessment of genotoxic hazards.
Gamze Ates, Dorien Favyts, Giel Hendriks, Remco Derr, Birgit Mertens

Mutat Res Genet Toxicol Environ Mutagen· November 2016

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The Extended ToxTracker Assay Discriminates Between Induction of DNA Damage, Oxidative Stress, and Protein Misfolding.
Giel Hendriks, Remco S Derr, Branislav Misovic, Bruno Morolli, Fabienne M G R Calléja

Toxicol Sci· March 2016

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MicroRNA classifier and nomogram for metastasis prediction in colon cancer.
Inès J Goossens-Beumer, Remco S Derr, Henk P J Buermans, Jelle J Goeman, Stefan Böhringer

Cancer Epidemiol Biomarkers Prev· January 2015

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High nuclear expression levels of histone-modifying enzymes LSD1, HDAC2 and SIRT1 in tumor cells correlate with decreased survival and increased relapse in breast cancer patients.
Remco S Derr, Anneke Q van Hoesel, Anne Benard, Inès J Goossens-Beumer, Anita Sajet

BMC Cancer· August 2014

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