Publications by authors named "Ren Iwata"

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Transmembrane protein 106B amyloid is a potential off-target molecule of tau PET tracers in the choroid plexus.
Yuka Yokoyama, Ryuichi Harada, Kaede Kudo, Ren Iwata, Yukitsuka Kudo

Nucl Med Biol· May 2025

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Visualization of Apolipoprotein E-Binding Amyloid Plaques in Postmortem Alzheimer's Disease Brains Using a Novel Fluorescent Probe THK-5320.
Ryuichi Harada, Kaede Kudo, Gonzalo Carmona Soto, Ren Iwata, Kazuhiko Yanai

ACS Chem Neurosci· May 2025

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Preclinical Characterization of the Tau PET Tracer [F]SNFT-1: Comparison of Tau PET Tracers.
Ryuichi Harada, Pradith Lerdsirisuk, Yuki Shimizu, Yuka Yokoyama, Yiqing Du, Ren Iwata

J Nucl Med· September 2023

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Evaluation of 18F labeled glial fibrillary acidic protein binding nanobody and its brain shuttle peptide fusion proteins using a neuroinflammation rat model.
Takahiro Morito, Ryuichi Harada, Ren Iwata, Yoichi Ishikawa, Nobuyuki Okamura

PLoS One· June 2023

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Mutations in RZF1, a zinc-finger protein, reduce magnesium uptake in roots and translocation to shoots in rice.
Natsuko I Kobayashi, Hiroki Takagi, Xiaoyu Yang, Ayako Nishizawa-Yokoi, Tenta Segawa, Ren Iwata

Plant Physiol· May 2023

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Development of a versatile high-throughput mutagenesis assay with multiplexed short-read NGS using DNA-barcoded shuttle vector library amplified in .
Hidehiko Kawai, Ren Iwata, Shungo Ebi, Ryusei Sugihara, Shogo Masuda

Elife· October 2022

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Mutagenesis analysis of GMN motif in Arabidopsis thaliana Mg2+ transporter MRS2-1.
Xiaoyu Yang, Natsuko I Kobayashi, Yoshiki Hayashi, Koichi Ito, Yoshitaka Moriwaki, Ren Iwata

Biosci Biotechnol Biochem· June 2022

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The Role of Chirality of [F]SMBT-1 in Imaging of Monoamine Oxidase-B.
Ryuichi Harada, Yuki Shimizu, Yiqing Du, Yoichi Ishikawa, Ren Iwata

ACS Chem Neurosci· February 2022

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F-THK5351 Positron Emission Tomography Imaging in Neurodegenerative Tauopathies.
Michinori Ezura, Akio Kikuchi, Nobuyuki Okamura, Aiko Ishiki, Takafumi Hasegawa, Ren Iwata

Front Aging Neurosci· November 2021

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F-SMBT-1: A Selective and Reversible PET Tracer for Monoamine Oxidase-B Imaging.
Ryuichi Harada, Yoshimi Hayakawa, Michinori Ezura, Pradith Lerdsirisuk, Yiqing Du, Ren Iwata

J Nucl Med· February 2021

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Synthesis and evaluation of 2-pyrrolopyridinylquinoline derivatives as selective tau PET tracers for the diagnosis of Alzheimer's disease.
Pradith Lerdsirisuk, Ryuichi Harada, Yoshimi Hayakawa, Yuki Shimizu, Yoichi Ishikawa, Ren Iwata

Nucl Med Biol· February 2021

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Synthesis and pharmacokinetic characterisation of a fluorine-18 labelled brain shuttle peptide fusion dimeric affibody.
Takahiro Morito, Ryuichi Harada, Ren Iwata, Yiqing Du, Nobuyuki Okamura

Sci Rep· January 2021

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A concentration-based microscale method for F-nucleophilic substitutions and its testing on the one-pot radiosynthesis of [F]FET and [F]fallypride.
Ren Iwata, Kazunori Terasaki, Yoichi Ishikawa, Ryuichi Harada, Shozo Furumoto

Appl Radiat Isot· December 2020

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Short-Term Magnesium Deficiency Triggers Nutrient Retranslocation in .
Takaaki Ogura, Natsuko I Kobayashi, Christian Hermans, Yasunori Ichihashi, Arisa Shibata, Ren Iwata

Front Plant Sci· June 2020

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Site-Specific Labeling of F-18 Proteins Using a Supplemented Cell-Free Protein Synthesis System and O-2-[F]Fluoroethyl-L-Tyrosine: [F]FET-HER2 Affibody Molecule.
Ai Yanai, Ryuichi Harada, Ren Iwata, Takeo Yoshikawa, Yoichi Ishikawa

Mol Imaging Biol· June 2019

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Magnesium uptake characteristics in Arabidopsis revealed by Mg tracer studies.
Takaaki Ogura, Natsuko I Kobayashi, Hisashi Suzuki, Ren Iwata, Tomoko M Nakanishi

Planta· September 2018

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Practical microscale one-pot radiosynthesis of F-labeled probes.
Ren Iwata, Claudio Pascali, Kazunori Terasaki, Yoichi Ishikawa, Shozo Furumoto

J Labelled Comp Radiopharm· June 2018

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Neuroimaging-pathological correlations of [F]THK5351 PET in progressive supranuclear palsy.
Aiko Ishiki, Ryuichi Harada, Hideaki Kai, Naomi Sato, Tomoko Totsune, Ren Iwata

Acta Neuropathol Commun· June 2018

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Correlations of F-THK5351 PET with Postmortem Burden of Tau and Astrogliosis in Alzheimer Disease.
Ryuichi Harada, Aiko Ishiki, Hideaki Kai, Naomi Sato, Katsutoshi Furukawa, Ren Iwata

J Nucl Med· April 2018

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Continuous-Flow Synthesis of N-Succinimidyl 4-[18F]fluorobenzoate Using a Single Microfluidic Chip.
Hiroyuki Kimura, Kenji Tomatsu, Hidekazu Saiki, Kenji Arimitsu, Masahiro Ono, Ren Iwata

PLoS One· August 2017

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A comparison of five partial volume correction methods for Tau and Amyloid PET imaging with [F]THK5351 and [C]PIB.
Miho Shidahara, Benjamin A Thomas, Nobuyuki Okamura, Masanobu Ibaraki, Keisuke Matsubara, Ren Iwata

Ann Nucl Med· August 2017

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Minimization of the amount of Kryptofix 222 - KHCO for applications to microscale F-radiolabeling.
Ren Iwata, Claudio Pascali, Kazunori Terasaki, Yoichi Ishikawa, Shozo Furumoto

Appl Radiat Isot· July 2017

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Erratum to: Characterization of the radiolabeled metabolite of tau PET tracer 18F-THK5351.
Ryuichi Harada, Shozo Furumoto, Tetsuro Tago, Katsutoshi Furukawa, Aiko Ishiki, Ren Iwata

Eur J Nucl Med Mol Imaging· January 2017

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Characterization of the radiolabeled metabolite of tau PET tracer F-THK5351.
Ryuichi Harada, Shozo Furumoto, Tetsuro Tago, Katsutoshi Furukawa, Aiko Ishiki, Ren Iwata

Eur J Nucl Med Mol Imaging· November 2016

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In vivo visualization of tau deposits in corticobasal syndrome by 18F-THK5351 PET.
Akio Kikuchi, Nobuyuki Okamura, Takafumi Hasegawa, Ryuichi Harada, Shoichi Watanuki, Ren Iwata

Neurology· November 2016

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