Publications by authors named "Rene van der Merwe"

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Pharmacokinetic and Pharmacodynamic Modeling of Tezepelumab to Guide Phase 3 Dose Selection for Patients With Severe Asthma.
Neang Ly, Yanan Zheng, Janet M Griffiths, Rene van der Merwe, Balaji Agoram

J Clin Pharmacol· July 2021

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Health-related quality of life with tralokinumab in moderate-to-severe atopic dermatitis: A phase 2b randomized study.
Jonathan I Silverberg, Emma Guttman-Yassky, Melinda Gooderham, Margitta Worm, Stephanie Rippon, René van der Merwe

Ann Allergy Asthma Immunol· May 2021

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Tezepelumab improves patient-reported outcomes in patients with severe, uncontrolled asthma in PATHWAY.
Jonathan Corren, Esther Garcia Gil, Janet M Griffiths, Jane R Parnes, Rene van der Merwe

Ann Allergy Asthma Immunol· February 2021

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Sputum is reduced in COPD following treatment with benralizumab.
Leena George, Adam Wright, Vijay Mistry, Amanda Sutcliffe, Latifa Chachi, René van der Merwe

Int J Chron Obstruct Pulmon Dis· January 2020

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Tezepelumab, an anti-thymic stromal lymphopoietin monoclonal antibody, in the treatment of moderate to severe atopic dermatitis: A randomized phase 2a clinical trial.
Eric L Simpson, Jane R Parnes, Dewei She, Sarah Crouch, William Rees, René van der Merwe

J Am Acad Dermatol· April 2019

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Treatment of atopic dermatitis with tralokinumab, an anti-IL-13 mAb.
Andreas Wollenberg, Michael D Howell, Emma Guttman-Yassky, Jonathan I Silverberg, Christopher Kell, René van der Merwe

J Allergy Clin Immunol· January 2019

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Tezepelumab in Adults with Uncontrolled Asthma.
Jonathan Corren, Jane R Parnes, Liangwei Wang, May Mo, Stephanie L Roseti, René van der Merwe

N Engl J Med· September 2017

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A randomised, placebo-controlled trial of anti-interleukin-1 receptor 1 monoclonal antibody MEDI8968 in chronic obstructive pulmonary disease.
Peter M A Calverley, Sanjay Sethi, Michelle Dawson, Christine K Ward, Donna K Finch, René van der Merwe

Respir Res· August 2017

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Efficacy and Safety of MEDI2070, an Antibody Against Interleukin 23, in Patients With Moderate to Severe Crohn's Disease: A Phase 2a Study.
Bruce E Sands, Jingjing Chen, Brian G Feagan, Mark Penney, William A Rees, René van der Merwe

Gastroenterology· July 2017

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Tralokinumab pharmacokinetics and tolerability when administered by different subcutaneous injection methods and rates
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Meena Jain, Diane Doughty, Corbin Clawson, Xiaobai Li, Nicholas White, René van der Merwe

Int J Clin Pharmacol Ther· July 2017

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Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study.
Christopher E Brightling, Eugene R Bleecker, Reynold A Panettieri, Mona Bafadhel, Dewei She, René van der Merwe

Lancet Respir Med· November 2014

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Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study.
Mario Castro, Sally E Wenzel, Eugene R Bleecker, Emilio Pizzichini, Piotr Kuna, René van der Merwe

Lancet Respir Med· November 2014

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Challenge models to assess new therapies in chronic obstructive pulmonary disease.
René van der Merwe, Nestor A Molfino

Int J Chron Obstruct Pulmon Dis· January 2013

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