Publications by authors named "Richard Bridges"

Claim this Profile
I
Inhibition of the Vesicular Glutamate Transporter (VGLUT) with Congo Red Analogs: New Binding Insights.
David M Hitt, Jeffery D Zwicker, Chih-Kai Chao, Sarjubhai A Patel, John M Gerdes, Richard J Bridges

Neurochem Res· March 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A functional long-term 2D serum-free human hepatic in vitro system for drug evaluation.
Carlota Oleaga, L Richard Bridges, Keisha Persaud, Christopher W McAleer, Christopher J Long

Biotechnol Prog· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships.
Christopher W McAleer, Amy Pointon, Christopher J Long, Rocky L Brighton, Benjamin D Wilkin, L Richard Bridges

Sci Rep· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics.
Christopher W McAleer, Christopher J Long, Daniel Elbrecht, Trevor Sasserath, L Richard Bridges

Sci Transl Med· June 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Long-Term Electrical and Mechanical Function Monitoring of a Human-on-a-Chip System.
Carlota Oleaga, Andrea Lavado, Anne Riu, Sandra Rothemund, Carlos A Carmona-Moran, L Richard Bridges

Adv Funct Mater· February 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system.
Carlota Oleaga, Anne Riu, Sandra Rothemund, Andrea Lavado, Christopher W McAleer, L Richard Bridges

Biomaterials· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs.
Carlota Oleaga, Catia Bernabini, Alec S T Smith, Balaji Srinivasan, Max Jackson, Richard Bridges

Sci Rep· February 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The development of benzo- and naphtho-fused quinoline-2,4-dicarboxylic acids as vesicular glutamate transporter (VGLUT) inhibitors reveals a possible role for neuroactive steroids.
Christina N Carrigan, Sarjubhai A Patel, Holly D Cox, Erin S Bolstad, John M Gerdes, Richard J Bridges

Bioorg Med Chem Lett· February 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Microwave accelerated synthesis of isoxazole hydrazide inhibitors of the system xc- transporter: Initial homology model.
Afnan A Matti, Joseph Mirzaei, John Rudolph, Stephen A Smith, Jayme L Newell, Richard J Bridges

Bioorg Med Chem Lett· November 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish.
Seok-Hyung Kim, Marie L Kowalski, Robert P Carson, L Richard Bridges, Kevin C Ess

Dis Model Mech· July 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signaling.
Richard Bridges, Victoria Lutgen, Doug Lobner, David A Baker

Pharmacol Rev· July 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Coupling biomarkers and drug action for neurodegenerative disease therapies: does the nose know?: Commentary on Sattler et al.: human nasal olfactory epithelium as a dynamic marker for CNS therapy development.
Fernando Cardozo-Pelaez, Richard J Bridges

Exp Neurol· June 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sulfasalazine for brain cancer fits.
Harald Sontheimer, Richard J Bridges

Expert Opin Investig Drugs· May 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
System xc⁻ cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS.
Richard J Bridges, Nicholas R Natale, Sarjubhai A Patel

Br J Pharmacol· January 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Increased excitatory amino acid transport into murine prion protein knockout astrocytes cultured in vitro.
Melissa S Pathmajeyan, Sarjubhai A Patel, James A Carroll, Todd Seib, James F Striebel, Richard J Bridges

Glia· November 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Regulation of the system x(C)- cystine/glutamate exchanger by intracellular glutathione levels in rat astrocyte primary cultures.
Todd Michael Seib, Sarjubhai Amratbhai Patel, Richard James Bridges

Glia· October 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Use of the hydantoin isostere to produce inhibitors showing selectivity toward the vesicular glutamate transporter versus the obligate exchange transporter system x(c)(-).
S Kaleem Ahmed, Jean-Louis G Etoga, Sarjubhai A Patel, Richard J Bridges, Charles M Thompson

Bioorg Med Chem Lett· July 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional expression, purification and high sequence coverage mass spectrometric characterization of human excitatory amino acid transporter EAAT2.
Ran Ye, Joseph F Rhoderick, Charles M Thompson, Richard J Bridges

Protein Expr Purif· November 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system x(c)(-) over the vesicular glutamate transporter.
Jean-Louis G Etoga, S Kaleem Ahmed, Sarjubhai Patel, Richard J Bridges, Charles M Thompson

Bioorg Med Chem Lett· April 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Isoxazole analogues bind the system xc- transporter: structure-activity relationship and pharmacophore model.
Sarjubhai A Patel, Trideep Rajale, Erin O'Brien, David J Burkhart, Jared K Nelson, Richard J Bridges

Bioorg Med Chem· January 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Ethyl 4-{1-[(2,4-dinitro-phen-yl)hydrazono]eth-yl}-5-(2-naphthyl-methoxy-meth-yl)isoxazole-3-carboxyl-ate.
Nicholas R Natale, Monica I Szabon-Watola, Brendan Twamley, Richard J Bridges, Sarjubhai Patel

Acta Crystallogr Sect E Struct Rep Online· December 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and preliminary pharmacological evaluation of novel derivatives of L-beta-threo-benzylaspartate as inhibitors of the neuronal glutamate transporter EAAT3.
Terri L Mavencamp, Joseph F Rhoderick, Richard J Bridges, C Sean Esslinger

Bioorg Med Chem· August 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Regional distribution of sodium-dependent excitatory amino acid transporters in rat spinal cord.
Susan A Queen, J Patrick Kesslak, Richard J Bridges

J Spinal Cord Med· October 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The substituted aspartate analogue L-beta-threo-benzyl-aspartate preferentially inhibits the neuronal excitatory amino acid transporter EAAT3.
C Sean Esslinger, Shailesh Agarwal, John Gerdes, Paul A Wilson, Erin S Davis, Richard J Bridges

Neuropharmacology· November 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The excitatory amino acid transporters: pharmacological insights on substrate and inhibitor specificity of the EAAT subtypes.
Richard J Bridges, C Sean Esslinger

Pharmacol Ther· September 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis