Publications by authors named "Richard Callaghan"

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Biochemical interactions between the Atm1-like transporter from Novosphingobium aromaticivorans and heavy metals.
Sarah Rottet, Shagufta Iqbal, Rachel Xifaras, Michael T Singer, Colin Scott, Richard Callaghan

Arch Biochem Biophys· August 2023

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Regulation of P-Glycoprotein in the Brain.
Amanda B Chai, Richard Callaghan, Ingrid C Gelissen

Int J Mol Sci· November 2022

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Vinca alkaloid binding to P-glycoprotein occurs in a processive manner.
Shagufta Iqbal, Caitlin Flux, Deborah A Briggs, Evelyne Deplazes, Jiansi Long, Richard Callaghan

Biochim Biophys Acta Biomembr· October 2022

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Corrigendum to "Regulation of ABCG4 transporter expression by sterols and LXR ligands" [PMID: 33141061, DOI: 10.1016/j.bbagen.2020.129769].
Alryel Yang, Amjad Z Alrosan, Laura J Sharpe, Andrew J Brown, Richard Callaghan

Biochim Biophys Acta Gen Subj· August 2022

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The Ubiquitin E3 Ligase Nedd4 Regulates the Expression and Amyloid-β Peptide Export Activity of P-Glycoprotein.
Amanda B Chai, Richard Callaghan, Ingrid C Gelissen

Int J Mol Sci· January 2022

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1,3-Benzodioxole-Modified Noscapine Analogues: Synthesis, Antiproliferative Activity, and Tubulin-Bound Structure.
Cassandra Yong, Shane M Devine, Anne-Catherine Abel, Stefan D Tomlins, Divya Muthiah, Richard Callaghan

ChemMedChem· September 2021

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Exploiting the metabolic energy demands of drug efflux pumps provides a strategy to overcome multidrug resistance in cancer.
Xuexin Gao, Doriane Aguanno, Mary Board, Richard Callaghan

Biochim Biophys Acta Gen Subj· August 2021

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Craniofacial morphology does not support a pre-contact Carib "invasion" of the northern Caribbean.
Christina M Giovas, Scott M Fitzpatrick, Thomas P Leppard, Mark Hubbe, William J Pestle, Richard T Callaghan

Sci Rep· August 2021

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UCP2 - Taking the heat out of P-glycoprotein?
Richard Callaghan, Mary Board

Cancer Drug Resist· June 2021

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The utilisation of glutamine and glucose by a 3-D tumour model trapped in quiescence.
Hannah Smith, David De Souza, Dedreia Tull, Malcolm McConville, Andrea Pellagatti, Richard Callaghan

Int J Biochem Cell Biol· April 2021

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Regulation of ABCG4 transporter expression by sterols and LXR ligands.
Alryel Yang, Amjad Z Alrosan, Laura J Sharpe, Andrew J Brown, Richard Callaghan

Biochim Biophys Acta Gen Subj· January 2021

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Mamma Mia, P-glycoprotein binds again.
Richard Callaghan, Ingrid C Gelissen, Anthony M George, Anika M S Hartz

FEBS Lett· December 2020

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New Evidence for P-gp-Mediated Export of Amyloid-β PEPTIDES in Molecular, Blood-Brain Barrier and Neuronal Models.
Amanda B Chai, Anika M S Hartz, Xuexin Gao, Alryel Yang, Richard Callaghan

Int J Mol Sci· December 2020

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Cross-linking, DEER-spectroscopy and molecular dynamics confirm the inward facing state of P-glycoprotein in a lipid membrane.
Alex R Carey Hulyer, Deborah A Briggs, Megan L O'Mara, Ian D Kerr, Jeffrey R Harmer, Richard Callaghan

J Struct Biol· July 2020

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Characterisation of Hybrid Polymersome Vesicles Containing the Efflux Pumps NaAtm1 or P-Glycoprotein.
Sarah Rottet, Shagufta Iqbal, Paul A Beales, Anran Lin, Jiwon Lee, Richard Callaghan

Polymers (Basel)· May 2020

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P-glycoprotein: a role in the export of amyloid-β in Alzheimer's disease?
Amanda B Chai, Gavin K F Leung, Richard Callaghan, Ingrid C Gelissen

FEBS J· February 2020

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A Novel Class of N-Sulfonyl and N-Sulfamoyl Noscapine Derivatives that Promote Mitotic Arrest in Cancer Cells.
Cassandra Yong, Shane M Devine, Xuexin Gao, Angelina Yan, Richard Callaghan

ChemMedChem· December 2019

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Psoralen-loaded lipid-polymer hybrid nanoparticles enhance doxorubicin efficacy in multidrug-resistant HepG2 cells.
Yueling Yuan, Tiange Cai, Richard Callaghan, Qianwen Li, Yinghong Huang

Int J Nanomedicine· May 2019

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Overcoming P-Glycoprotein-Mediated Drug Resistance with Noscapine Derivatives.
Divya Muthiah, Georgia K Henshaw, Aaron J DeBono, Ben Capuano, Peter J Scammells, Richard Callaghan

Drug Metab Dispos· February 2019

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Methods of reconstitution to investigate membrane protein function.
Ruth Skrzypek, Shagufta Iqbal, Richard Callaghan

Methods· September 2018

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Synthesis and Pharmacological Evaluation of Noscapine-Inspired 5-Substituted Tetrahydroisoquinolines as Cytotoxic Agents.
Shane M Devine, Cassandra Yong, Dzifa Amenuvegbe, Luigi Aurelio, Divya Muthiah, Richard Callaghan

J Med Chem· September 2018

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Fabrication of psoralen-loaded lipid-polymer hybrid nanoparticles and their reversal effect on drug resistance of cancer cells.
Yueling Yuan, Peter Chiba, Tiange Cai, Richard Callaghan, Li Bai

Oncol Rep· August 2018

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Dual effects of the PI3K inhibitor ZSTK474 on multidrug efflux pumps in resistant cancer cells.
Divya Muthiah, Richard Callaghan

Eur J Pharmacol· November 2017

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Acetoacetate is a more efficient energy-yielding substrate for human mesenchymal stem cells than glucose and generates fewer reactive oxygen species.
Mary Board, Colleen Lopez, Christian van den Bos, Richard Callaghan, Kieran Clarke

Int J Biochem Cell Biol· July 2017

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The "pushmi-pullyu" of resistance to chloroquine in malaria.
Ruth Skrzypek, Richard Callaghan

Essays Biochem· February 2017

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