Publications by authors named "Richard D Bunker"

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Machine learning to predict de novo protein-protein interactions.
Pablo Gainza, Richard D Bunker, Sharon A Townson, John C Castle

Trends Biotechnol· December 2025

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A degron-mimicking molecular glue drives CRBN homo-dimerization and degradation.
Gerasimos Langousis, Pablo Gainza, Moritz Hunkeler, Despoina Kapsitidou, Etienne J Donckele, Richard D Bunker

Nat Commun· November 2025

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Mining the CRBN target space redefines rules for molecular glue-induced neosubstrate recognition.
Georg Petzold, Pablo Gainza, Stefano Annunziato, Ilaria Lamberto, Peter Trenh, Richard D Bunker

Science· July 2025

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The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K.
Mikołaj Słabicki, Zuzanna Kozicka, Georg Petzold, Yen-Der Li, Manisha Manojkumar, Richard D Bunker

Nature· September 2020

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Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Alicia K Michael, Ralph S Grand, Luke Isbel, Simone Cavadini, Zuzanna Kozicka, Richard D Bunker

Science· June 2020

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Regulation of human 4-hydroxy-2-oxoglutarate aldolase by pyruvate and α-ketoglutarate: implications for primary hyperoxaluria type-3.
Amadeus Huang, Julia Burke, Richard D Bunker, Yee-Foong Mok, Michael D Griffin

Biochem J· November 2019

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Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation.
Julius Rabl, Richard D Bunker, Andreas D Schenk, Simone Cavadini, Mark E Gill

Mol Cell· August 2019

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DNA damage detection in nucleosomes involves DNA register shifting.
Syota Matsumoto, Simone Cavadini, Richard D Bunker, Ralph S Grand, Alessandro Potenza

Nature· July 2019

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Publisher Correction: DNA damage detection in nucleosomes involves DNA register shifting.
Syota Matsumoto, Simone Cavadini, Richard D Bunker, Ralph S Grand, Alessandro Potenza

Nature· July 2019

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Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN.
Quinlan L Sievers, Georg Petzold, Richard D Bunker, Aline Renneville, Mikołaj Słabicki

Science· November 2018

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Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends.
Stefano Mattarocci, Julia K Reinert, Richard D Bunker, Gabriele A Fontana, Tianlai Shi

Nat Struct Mol Biol· July 2017

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Atomic structure of granulin determined from native nanocrystalline granulovirus using an X-ray free-electron laser.
Cornelius Gati, Dominik Oberthuer, Oleksandr Yefanov, Richard D Bunker, Francesco Stellato

Proc Natl Acad Sci U S A· February 2017

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Tackling the crystallographic structure determination of the COP9 signalosome.
Richard D Bunker

Acta Crystallogr D Struct Biol· March 2016

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Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome.
Simone Cavadini, Eric S Fischer, Richard D Bunker, Alessandro Potenza, Gondichatnahalli M Lingaraju

Nature· March 2016

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A functional role of Rv1738 in Mycobacterium tuberculosis persistence suggested by racemic protein crystallography.
Richard D Bunker, Kalyaneswar Mandal, Ghader Bashiri, Jessica J Chaston, Bradley L Pentelute

Proc Natl Acad Sci U S A· April 2015

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Structural basis for the enhancement of virulence by viral spindles and their in vivo crystallization.
Elaine Chiu, Marcel Hijnen, Richard D Bunker, Marion Boudes, Chitra Rajendran

Proc Natl Acad Sci U S A· March 2015

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Crystal structure of the human COP9 signalosome.
Gondichatnahalli M Lingaraju, Richard D Bunker, Simone Cavadini, Daniel Hess, Ulrich Hassiepen

Nature· August 2014

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Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1.
Nicolas Bocquet, Anna H Bizard, Wassim Abdulrahman, Nicolai B Larsen, Mahamadou Faty, Richard D Bunker

Nat Struct Mol Biol· March 2014

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Purification, crystallization and preliminary X-ray studies of MbtN (Rv1346) from Mycobacterium tuberculosis.
Ai Fen Chai, Jodie M Johnston, Richard D Bunker, Esther M M Bulloch, Genevieve L Evans

Acta Crystallogr Sect F Struct Biol Cryst Commun· December 2013

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Rif1 and Rif2 shape telomere function and architecture through multivalent Rap1 interactions.
Tianlai Shi, Richard D Bunker, Stefano Mattarocci, Cyril Ribeyre, Mahamadou Faty

Cell· June 2013

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Structure and function of human xylulokinase, an enzyme with important roles in carbohydrate metabolism.
Richard D Bunker, Esther M M Bulloch, James M J Dickson, Kerry M Loomes, Edward N Baker

J Biol Chem· January 2013

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Use of a repetitive seeding protocol to obtain diffraction-quality crystals of a putative human D-xylulokinase.
Richard D Bunker, James M J Dickson, Tom T Caradoc-Davies, Kerry M Loomes, Edward N Baker

Acta Crystallogr Sect F Struct Biol Cryst Commun· October 2012

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Purification, crystallization and preliminary crystallographic analysis of human dihydrodipicolinate synthase-like protein (DHDPSL).
Richard D Bunker, Kerry M Loomes, Edward N Baker

Acta Crystallogr Sect F Struct Biol Cryst Commun· January 2012

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The physiological substrates of fructosamine-3-kinase-related-protein (FN3KRP) are intermediates of nonenzymatic reactions between biological amines and ketose sugars (fructation products).
Benjamin S Szwergold, Richard D Bunker, Kerry M Loomes

Med Hypotheses· November 2011

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Histone methylation by PRC2 is inhibited by active chromatin marks.
Frank W Schmitges, Archana B Prusty, Mahamadou Faty, Alexandra Stützer, Gondichatnahalli M Lingaraju, Richard D Bunker

Mol Cell· May 2011

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