Publications by authors named "Simone Cavadini"

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Nucleosomes specify co-factor access to p53.
Deyasini Chakraborty, Colby R Sandate, Luke Isbel, Georg Kempf, Joscha Weiss, Simone Cavadini

Mol Cell· August 2025

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Deep quantification of substrate turnover defines protease subsite cooperativity.
Rajani Kanth Gudipati, Dimos Gaidatzis, Jan Seebacher, Sandra Muehlhaeusser, Georg Kempf, Simone Cavadini

Mol Syst Biol· December 2024

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The genetic architecture of protein interaction affinity and specificity.
Alexandra M Bendel, Andre J Faure, Dominique Klein, Kenji Shimada, Romane Lyautey, Simone Cavadini

Nat Commun· October 2024

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Designing Rigid DNA Origami Templates for Molecular Visualization Using Cryo-EM.
Ali Khoshouei, Georg Kempf, Volodymyr Mykhailiuk, Johanna Mariko Griessing, Maximilian Nicolas Honemann, Simone Cavadini

Nano Lett· April 2024

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UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Jonathan M Tsai, Jacob D Aguirre, Yen-Der Li, Jared Brown, Vivian Focht, Simone Cavadini

Mol Cell· August 2023

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Cooperation between bHLH transcription factors and histones for DNA access.
Alicia K Michael, Lisa Stoos, Priya Crosby, Nikolas Eggers, Xinyu Y Nie, Simone Cavadini

Nature· July 2023

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Recognition of the CCT5 di-Glu degron by CRL4 is dependent on TRiC assembly.
Carlos Pla-Prats, Simone Cavadini, Georg Kempf, Nicolas H Thomä

EMBO J· February 2023

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Structure of the ciliogenesis-associated CPLANE complex.
Gerasimos Langousis, Simone Cavadini, Niels Boegholm, Esben Lorentzen, Georg Kempf

Sci Adv· April 2022

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The CRL4 cullin-RING ubiquitin ligase is activated following a switch in oligomerization state.
Weaam I Mohamed, Andreas D Schenk, Georg Kempf, Simone Cavadini, Anja Basters

EMBO J· November 2021

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Structural basis of human separase regulation by securin and CDK1-cyclin B1.
Jun Yu, Pierre Raia, Chloe M Ghent, Tobias Raisch, Yashar Sadian, Simone Cavadini

Nature· August 2021

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Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture.
Julia Nörpel, Simone Cavadini, Andreas D Schenk, Alexandra Graff-Meyer, Daniel Hess

PLoS Biol· July 2021

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Dynamic association of human Ebp1 with the ribosome.
Varun Bhaskar, Jessica Desogus, Alexandra Graff-Meyer, Andreas D Schenk, Simone Cavadini

RNA· April 2021

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Structural mechanism of cGAS inhibition by the nucleosome.
Ganesh R Pathare, Alexiane Decout, Selene Glück, Simone Cavadini, Kristina Makasheva

Nature· November 2020

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Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Alicia K Michael, Ralph S Grand, Luke Isbel, Simone Cavadini, Zuzanna Kozicka

Science· June 2020

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Live Analysis and Reconstruction of Single-Particle Cryo-Electron Microscopy Data with CryoFLARE.
Andreas D Schenk, Simone Cavadini, Nicolas H Thomä, Christel Genoud

J Chem Inf Model· May 2020

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Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
Varun Bhaskar, Alexandra Graff-Meyer, Andreas D Schenk, Simone Cavadini, Ottilie von Loeffelholz

Cell Rep· April 2020

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Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation.
Julius Rabl, Richard D Bunker, Andreas D Schenk, Simone Cavadini, Mark E Gill

Mol Cell· August 2019

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DNA damage detection in nucleosomes involves DNA register shifting.
Syota Matsumoto, Simone Cavadini, Richard D Bunker, Ralph S Grand, Alessandro Potenza

Nature· July 2019

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Publisher Correction: DNA damage detection in nucleosomes involves DNA register shifting.
Syota Matsumoto, Simone Cavadini, Richard D Bunker, Ralph S Grand, Alessandro Potenza

Nature· July 2019

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Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends.
Stefano Mattarocci, Julia K Reinert, Richard D Bunker, Gabriele A Fontana, Tianlai Shi, Simone Cavadini

Nat Struct Mol Biol· July 2017

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Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome.
Simone Cavadini, Eric S Fischer, Richard D Bunker, Alessandro Potenza, Gondichatnahalli M Lingaraju

Nature· March 2016

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Crystal structure of the human COP9 signalosome.
Gondichatnahalli M Lingaraju, Richard D Bunker, Simone Cavadini, Daniel Hess, Ulrich Hassiepen

Nature· August 2014

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Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide.
Eric S Fischer, Kerstin Böhm, John R Lydeard, Haidi Yang, Michael B Stadler, Simone Cavadini

Nature· August 2014

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Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1.
Nicolas Bocquet, Anna H Bizard, Wassim Abdulrahman, Nicolai B Larsen, Mahamadou Faty, Simone Cavadini

Nat Struct Mol Biol· March 2014

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The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation.
Eric S Fischer, Andrea Scrima, Kerstin Böhm, Syota Matsumoto, Gondichatnahalli M Lingaraju, Simone Cavadini

Cell· November 2011

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