Publications by authors named "Richard D Rainbow"

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Trimethylamine N-oxide (TMAO) acutely alters ionic currents but does not increase cardiac cell death.
Simona Esposito, Lauren R McGuinness, Parveen Sharma, Amy E Chadwick, Richard D Rainbow

Front Physiol· February 2025

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Identification and characterisation of functional K6.1-containing ATP-sensitive potassium channels in the cardiac ventricular sarcolemmal membrane.
Sean Brennan, Shen Chen, Samir Makwana, Simona Esposito, Lauren R McGuinness, Richard D Rainbow

Br J Pharmacol· September 2024

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Editorial: Insulin resistance and cardiovascular disease.
Alan J Stewart, Erkan Tuncay, Samantha J Pitt, Richard D Rainbow

Front Endocrinol (Lausanne)· August 2023

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Slowly activating voltage-gated potassium current potentiation by ML277 is a novel cardioprotective intervention.
Sean Brennan, Abrar I M Alnaimi, Lauren R McGuinness, Muhammad I M Abdelaziz, Robert A McKenzie, Richard D Rainbow

PNAS Nexus· May 2023

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Mitigation of Cardiovascular Disease and Toxicity through NRF2 Signalling.
James A Roberts, Richard D Rainbow, Parveen Sharma

Int J Mol Sci· April 2023

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The integrin ligand SVEP1 regulates GPCR-mediated vasoconstriction via integrins α9β1 and α4β1.
Gavin E Morris, Matthew J Denniff, Elisavet Karamanavi, Sarah A Andrews, Renata B Kostogrys, Richard D Rainbow

Br J Pharmacol· November 2022

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Selective protein kinase C inhibition switches time-dependent glucose cardiotoxicity to cardioprotection.
Sean Brennan, Simona Esposito, Muhammad I M Abdelaziz, Christopher A Martin, Samir Makwana, Richard D Rainbow

Front Cardiovasc Med· September 2022

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Kir6.2-D323 and SUR2A-Q1336: an intersubunit interaction pairing for allosteric information transfer in the KATP channel complex.
Sean Brennan, Hussein N Rubaiy, Saba Imanzadeh, Ruth Reid, David Lodwick, Richard D Rainbow

Biochem J· February 2020

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Deep-Channel uses deep neural networks to detect single-molecule events from patch-clamp data.
Numan Celik, Fiona O'Brien, Sean Brennan, Richard D Rainbow, Caroline Dart

Commun Biol· January 2020

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A novel form of glycolytic metabolism-dependent cardioprotection revealed by PKCα and β inhibition.
Sean Brennan, Shen Chen, Samir Makwana, Christopher A Martin, Mark W Sims, Richard D Rainbow

J Physiol· September 2019

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Small-Molecule G Protein-Coupled Receptor Kinase Inhibitors Attenuate G Protein-Coupled Receptor Kinase 2-Mediated Desensitization of Vasoconstrictor-Induced Arterial Contractions.
Richard D Rainbow, Sean Brennan, Robert Jackson, Alison J Beech, Amal Bengreed

Mol Pharmacol· September 2018

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Ca2+ dependent but PKC independent signalling mediates UTP induced contraction of rat mesenteric arteries.
Fouzia Panhwar, Richard D Rainbow, Robert Jackson, Noel W Davies

J Smooth Muscle Res· May 2016

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Distinct and complementary roles for α and β isoenzymes of PKC in mediating vasoconstrictor responses to acutely elevated glucose.
Robert Jackson, Sean Brennan, Peter Fielding, Mark W Sims, R A John Challiss, Richard D Rainbow

Br J Pharmacol· March 2016

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Response to Qian and Colvin: Zinc-mediated Regulation of the Cardiac Ryanodine Receptor Occurs via Multiple Binding Sites.
Jason Woodier, Richard D Rainbow, Alan J Stewart, Samantha J Pitt

J Biol Chem· February 2016

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Detachment of surface membrane invagination systems by cationic amphiphilic drugs.
Sangar Osman, Kirk A Taylor, Natalie Allcock, Richard D Rainbow, Martyn P Mahaut-Smith

Sci Rep· January 2016

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Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension.
Jonathon M Willets, Craig A Nash, Richard D Rainbow, Carl P Nelson, R A John Challiss

Am J Physiol Cell Physiol· August 2015

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Intracellular Zinc Modulates Cardiac Ryanodine Receptor-mediated Calcium Release.
Jason Woodier, Richard D Rainbow, Alan J Stewart, Samantha J Pitt

J Biol Chem· July 2015

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Early opening of sarcolemmal ATP-sensitive potassium channels is not a key step in PKC-mediated cardioprotection.
Sean Brennan, Robert Jackson, Manish Patel, Mark W Sims, Diane Hudman, Richard D Rainbow

J Mol Cell Cardiol· February 2015

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Sulfonylurea receptors regulate the channel pore in ATP-sensitive potassium channels via an intersubunit salt bridge.
David Lodwick, Richard D Rainbow, Hussein N Rubaiy, Mohammed Al Johi, Geerten W Vuister

Biochem J· December 2014

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PKC-mediated toxicity of elevated glucose concentration on cardiomyocyte function.
Mark W Sims, James Winter, Sean Brennan, Robert I Norman, G André Ng, Richard D Rainbow

Am J Physiol Heart Circ Physiol· August 2014

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Kir6.2 limits Ca(2+) overload and mitochondrial oscillations of ventricular myocytes in response to metabolic stress.
Nina M Storey, Rebecca C Stratton, Richard D Rainbow, Nicholas B Standen, David Lodwick

Am J Physiol Heart Circ Physiol· November 2013

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Combined calcium fluorescence recording with ionic currents in contractile cells.
Richard D Rainbow

Methods Mol Biol· February 2013

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Principal role of adenylyl cyclase 6 in K⁺ channel regulation and vasodilator signalling in vascular smooth muscle cells.
Carl P Nelson, Richard D Rainbow, Jennifer L Brignell, Matthew D Perry, Jonathon M Willets

Cardiovasc Res· September 2011

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The sarcoplasmic reticulum Ca2+ store arrangement in vascular smooth muscle.
Richard D Rainbow, Debbi Macmillan, John G McCarron

Cell Calcium· July 2010

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Endothelin-I and angiotensin II inhibit arterial voltage-gated K+ channels through different protein kinase C isoenzymes.
Richard D Rainbow, Robert I Norman, Diane E Everitt, Jennifer L Brignell, Noel W Davies

Cardiovasc Res· August 2009

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