Publications by authors named "Richard Harbottle"

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Generation and functional analysis of melanoma antigen-specific CD8+ T cells derived from S/MAR vector-transfected human induced pluripotent stem cells.
Juliane Poelchen, Sandra Pardo, Daniel Novak, Qian Sun, Tamara Steinfass, Richard Harbottle

Int J Cancer· November 2025

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Vaccine-induced T cell receptor T cell therapy targeting a glioblastoma stemness antigen.
Yu-Chan Chih, Amelie C Dietsch, Philipp Koopmann, Xiujian Ma, Dennis A Agardy, Richard Harbottle

Nat Commun· February 2025

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Feasibility of Direct Vitrectomy-Sparing Subretinal Injection for Gene Delivery in Large Animals.
Zbynek Stranak, Taras Ardan, Yaroslav Nemesh, Maria Toms, Lyes Toualbi, Richard Harbottle

Curr Eye Res· August 2024

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Novel chimeric antigen receptors for the effective and safe treatment of NY-BR-1 positive breast cancer.
Dirk Jäger, Aileen Berger, Alexandra Tuch, Claudia Luckner-Minden, Rosa Eurich, Richard Harbottle

Clin Transl Med· July 2024

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A Simple Nonviral Method to Generate Human Induced Pluripotent Stem Cells Using SMAR DNA Vectors.
Anna Hartley, Luisa Burger, Cornelia L Wincek, Lieke Dons, Tracy Li, Richard P Harbottle

Genes (Basel)· April 2024

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NLGN4X TCR transgenic T cells to treat gliomas.
Christoper Krämer, Michael Kilian, Yu-Chan Chih, Alexandros Kourtesakis, Dirk C Hoffmann, Richard Harbottle

Neuro Oncol· February 2024

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Gene Augmentation of CHM Using Non-Viral Episomal Vectors in Models of Choroideremia.
Lyes Toualbi, Maria Toms, Patrick Vingadas Almeida, Richard Harbottle, Mariya Moosajee

Int J Mol Sci· October 2023

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Successful large gene augmentation of USH2A with non-viral episomal vectors.
Maria Toms, Lyes Toualbi, Patrick V Almeida, Richard Harbottle, Mariya Moosajee

Mol Ther· September 2023

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Development of an Orthotopic HPV16-Dependent Base of Tongue Tumor Model in MHC-Humanized Mice.
Christoph Schifflers, Samantha Zottnick, Jonas D Förster, Sebastian Kruse, Ruwen Yang, Richard P Harbottle

Pathogens· January 2023

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Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs.
Tsunaki Hongu, Maren Pein, Jacob Insua-Rodríguez, Ewgenija Gutjahr, Greta Mattavelli, Richard Harbottle

Nat Cancer· April 2022

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Delivery of non-viral naked DNA vectors to liver in small weaned pigs by hydrodynamic retrograde intrabiliary injection.
Tatjana Chan, Hiu Man Grisch-Chan, Philipp Schmierer, Ulrike Subotic, Nicole Rimann, Richard Harbottle

Mol Ther Methods Clin Dev· March 2022

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An episomal DNA vector platform for the persistent genetic modification of pluripotent stem cells and their differentiated progeny.
Alicia Roig-Merino, Manuela Urban, Matthias Bozza, Julia D Peterson, Louise Bullen, Richard P Harbottle

Stem Cell Reports· January 2022

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Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors.
Christopher D Thornton, Stuart Fielding, Kinga Karbowniczek, Alicia Roig-Merino, Alysha E Burrows, Richard P Harbottle

Mol Ther Methods Clin Dev· December 2021

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Folliculin Controls the Intracellular Survival and Trans-Epithelial Passage of .
Tao Yang, Motaharehsadat Heydarian, Vera Kozjak-Pavlovic, Manuela Urban, Richard P Harbottle

Front Cell Infect Microbiol· June 2021

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A nonviral, nonintegrating DNA nanovector platform for the safe, rapid, and persistent manufacture of recombinant T cells.
Matthias Bozza, Alice De Roia, Margareta P Correia, Aileen Berger, Alexandra Tuch, Richard P Harbottle

Sci Adv· April 2021

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Novel Non-integrating DNA Nano-S/MAR Vectors Restore Gene Function in Isogenic Patient-Derived Pancreatic Tumor Models.
Matthias Bozza, Edward W Green, Elisa Espinet, Alice De Roia, Corinna Klein, Richard P Harbottle

Mol Ther Methods Clin Dev· June 2020

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Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate.
Lukas Bunse, Stefan Pusch, Theresa Bunse, Felix Sahm, Khwab Sanghvi, Richard Harbottle

Nat Med· August 2018

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The expression of genes contributing to pancreatic adenocarcinoma progression is influenced by the respective environment.
Micah N Sagini, Michael Zepp, Frank Bergmann, Matthias Bozza, Richard Harbottle

Genes Cancer· March 2018

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Beta HPV38 oncoproteins act with a hit-and-run mechanism in ultraviolet radiation-induced skin carcinogenesis in mice.
Daniele Viarisio, Karin Müller-Decker, Rosita Accardi, Alexis Robitaille, Matthias Dürst, Richard Harbottle

PLoS Pathog· January 2018

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Safety Profile of Stromal Hydration of Clear Corneal Incisions with Cefuroxime in the Mouse Model.
Mariya Moosajee, Dhani Tracey-White, Richard P Harbottle, Veronica Ferguson

J Ocul Pharmacol Ther· September 2016

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Sustained expression from DNA vectors.
Suet Ping Wong, Orestis Argyros, Richard P Harbottle

Adv Genet· September 2015

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Treatment of phenylketonuria using minicircle-based naked-DNA gene transfer to murine liver.
Hiu Man Viecelli, Richard P Harbottle, Suet Ping Wong, Andrea Schlegel, Marinee K Chuah

Hepatology· September 2014

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Birt-Hogg-Dube syndrome is a novel ciliopathy.
Monique N H Luijten, Sander G Basten, Tijs Claessens, Marigje Vernooij, Claire L Scott, Richard P Harbottle

Hum Mol Genet· November 2013

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Minimal-length Synthetic shRNAs Formulated with Lipid Nanoparticles are Potent Inhibitors of Hepatitis C Virus IRES-linked Gene Expression in Mice.
Anne Dallas, Heini Ilves, Joshua Shorenstein, Adam Judge, Ryan Spitler, Richard P Harbottle

Mol Ther Nucleic Acids· September 2013

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Genetic modification of dividing cells using episomally maintained S/MAR DNA vectors.
Suet-Ping Wong, Richard Paul Harbottle

Mol Ther Nucleic Acids· August 2013

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