Publications by authors named "Richard Leask"

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An Accessible Platform to Quantify Oxygen Diffusion in Cell-Laden Hydrogels and Its Application to Alginate-Immobilized Pancreatic Beta Cells.
Hamid Ebrahimi Orimi, Kurtis S Champion, Laurier Gauvin, Jonathan A Brassard, Berit L Strand, Richard L Leask

Biotechnol Bioeng· November 2025

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A Multidisciplinary Aortopathy Clinic: The McGill Experience.
Masaki Kodaira, Kevin Lachapelle, Richard L Leask, Kevin Bates, Yoni Grossman

CJC Open· July 2025

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Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization.
Brenden N Moeun, Florent Lemaire, Alexandra M Smink, Hamid Ebrahimi Orimi, Richard L Leask

J Tissue Eng· January 2025

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Empagliflozin reduces endoplasmic reticulum stress associated TXNIP/NLRP3 activation in tunicamycin-stimulated aortic endothelial cells.
Marc-Antoine Campeau, Richard L Leask

Naunyn Schmiedebergs Arch Pharmacol· January 2024

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Improving the 3D Printability of Sugar Glass to Engineer Sacrificial Vascular Templates.
Brenden N Moeun, Stephanie A Fernandez, Simon Collin, Gabrielle Gauvin-Rossignol, Theophraste Lescot, Richard L Leask

3D Print Addit Manuf· October 2023

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Thoracic Aortic Aneurysm Risk Assessment: A Machine Learning Approach.
Lauren Kennedy, Kevin Bates, Judith Therrien, Yoni Grossman, Masaki Kodaira, Richard L Leask

JACC Adv· October 2023

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Exposure to the non-phthalate plasticizer di-heptyl succinate is less disruptive to C57bl/6N mouse recovery from a myocardial infarction than DEHP, TOTM or related di-octyl succinate.
Adam Schwendt, Joey-Bahige Chammas, Milan Maric, Jim A Nicell, Richard Leask

PLoS One· July 2023

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Ultrasoft edge-labelled hydrogel sensors reveal internal tissue stress patterns in invasive engineered tumors.
Wontae Lee, Christina-Marie Boghdady, Virginie Lelarge, Richard L Leask, Luke McCaffrey

Biomaterials· May 2023

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Wall stresses of early remodeled pulmonary autografts.
Yue Xuan, Edgardo Alonso, Alexander Emmott, Zhongjie Wang, Shalni Kumar, Richard L Leask

J Thorac Cardiovasc Surg· December 2022

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Empagliflozin mitigates endothelial inflammation and attenuates endoplasmic reticulum stress signaling caused by sustained glycocalyx disruption.
Marc-Antoine Campeau, Richard L Leask

Sci Rep· July 2022

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3D printed ascending aortic simulators with physiological fidelity for surgical simulation.
Ali Alakhtar, Alexander Emmott, Cornelius Hart, Rosaire Mongrain, Richard L Leask

BMJ Simul Technol Enhanc Learn· June 2021

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An Perfused Macroencapsulation Device to Study Hemocompatibility and Survival of Islet-Like Cell Clusters.
Stephanie A Fernandez, Lisa Danielczak, Gabrielle Gauvin-Rossignol, Craig Hasilo, André Bégin-Drolet, Richard L Leask

Front Bioeng Biotechnol· May 2021

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Distinct Expression of Nonmuscle Myosin IIB in Pulmonary Arteries of Patients With Aortic Stenosis vs Insufficiency Undergoing a Ross Procedure.
Alexander Emmott, Vanessa Hertig, Alexandre Bergeron, Louis Villeneuve, Laurence Lefebvre, Richard L Leask

Can J Cardiol· January 2021

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Empagliflozin restores the integrity of the endothelial glycocalyx in vitro.
Scott Cooper, Hwee Teoh, Marc Antoine Campeau, Subodh Verma, Richard L Leask

Mol Cell Biochem· September 2019

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Increased MMP activity in curved geometries disrupts the endothelial cell glycocalyx creating a proinflammatory environment.
Scott Cooper, Alexander Emmott, Karli K McDonald, Marc-Antoine Campeau, Richard L Leask

PLoS One· February 2019

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Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures.
Wontae Lee, Nikita Kalashnikov, Stephanie Mok, Ruba Halaoui, Elena Kuzmin, Richard L Leask

Nat Commun· January 2019

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Histopathological and biomechanical properties of the aortic wall in 2 patients with chronic type A aortic dissection.
Alexander Emmott, Ismaïl El-Hamamsy, Richard L Leask

Cardiovasc Pathol· August 2018

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Transesophageal echocardiographic strain imaging predicts aortic biomechanics: Beyond diameter.
Alexander Emmott, Haitham Alzahrani, Mohammed Alreshidan, Judith Therrien, Richard L Leask

J Thorac Cardiovasc Surg· August 2018

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How Green is Your Plasticizer?
Roya Jamarani, Hanno C Erythropel, James A Nicell, Richard L Leask, Milan Marić

Polymers (Basel)· July 2018

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Designing Green Plasticizers: Linear Alkyl Diol Dibenzoate Plasticizers and a Thermally Reversible Plasticizer.
Hanno C Erythropel, Aurélie Börmann, Jim A Nicell, Richard L Leask, Milan Maric

Polymers (Basel)· June 2018

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3D printing materials and their use in medical education: a review of current technology and trends for the future.
Justine Garcia, ZhiLin Yang, Rosaire Mongrain, Richard L Leask, Kevin Lachapelle

BMJ Simul Technol Enhanc Learn· January 2018

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Stenosis Hemodynamics Disrupt the Endothelial Cell Glycocalyx by MMP Activity Creating a Proinflammatory Environment.
S Cooper, K McDonald, D Burkat, Richard L Leask

Ann Biomed Eng· September 2017

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Blood flow can signal during angiogenesis not only through mechanotransduction, but also by affecting growth factor distribution.
Siavash Ghaffari, Richard L Leask, Elizabeth A V Jones

Angiogenesis· August 2017

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Obtaining the biomechanical behavior of ascending aortic aneurysm via the use of novel speckle tracking echocardiography.
Mohammed Alreshidan, Nastaran Shahmansouri, Jennifer Chung, Vynka Lash, Alexander Emmott, Richard L Leask

J Thorac Cardiovasc Surg· April 2017

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Investigation on the Regional Loss Factor and Its Anisotropy for Aortic Aneurysms.
Nastaran Shahmansouri, Mohammed Alreshidan, Alexander Emmott, Kevin Lachapelle, Ismaïl El-Hamamsy, Richard L Leask

Materials (Basel)· October 2016

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