Publications by authors named "Luke McCaffrey"

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Gravity-based microfiltration reveals unexpected prevalence of circulating tumor cell clusters in ovarian and colorectal cancer.
Anne Meunier, Javier Alejandro Hernández-Castro, Nicholas Chahley, Laudine Communal, Sara Kheireddine, Luke McCaffrey

Commun Med (Lond)· February 2025

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Correction: MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma In Situ.
Qianyu Guo, Vivian Z Li, Jessica N Nichol, Fan Huang, William Yang, Luke McCaffrey

Cancer Res· April 2024

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LGN loss randomizes spindle orientation and accelerates tumorigenesis in PTEN-deficient epidermis.
Sophie Viala, Charlotte Hadjadj, Vandana Nathan, Marie-Christine Guiot, Luke McCaffrey

Mol Biol Cell· February 2024

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Ezh2 promotes mammary tumor initiation through epigenetic regulation of the Wnt and mTORC1 signaling pathways.
Linshan Liu, Bin Xiao, Alison Hirukawa, Harvey W Smith, Dongmei Zuo, Luke McCaffrey

Proc Natl Acad Sci U S A· August 2023

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Ultrasoft edge-labelled hydrogel sensors reveal internal tissue stress patterns in invasive engineered tumors.
Wontae Lee, Christina-Marie Boghdady, Virginie Lelarge, Richard L Leask, Luke McCaffrey

Biomaterials· May 2023

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Polarity in breast development and cancer.
Mara K M Whitford, Luke McCaffrey

Curr Top Dev Biol· April 2023

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3D chromatin remodeling potentiates transcriptional programs driving cell invasion.
Benjamin Lebeau, Maïka Jangal, Tiejun Zhao, Cheng Kit Wong, Nolan Wong, Luke McCaffrey

Proc Natl Acad Sci U S A· September 2022

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Deep Interpretable Classification and Weakly-Supervised Segmentation of Histology Images via Max-Min Uncertainty.
Soufiane Belharbi, Jerome Rony, Jose Dolz, Ismail Ben Ayed, Luke Mccaffrey

IEEE Trans Med Imaging· March 2022

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Studying Cell Polarity Dynamics During Cancer Initiation Using Inducible 3D Organotypic Cultures.
Rachel Catterall, Reem Kurdieh, Luke McCaffrey

Methods Mol Biol· February 2022

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Revisiting tissue tensegrity: Biomaterial-based approaches to measure forces across length scales.
Christina-Marie Boghdady, Nikita Kalashnikov, Stephanie Mok, Luke McCaffrey, Christopher Moraes

APL Bioeng· December 2021

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A proximity proteomics screen in three-dimensional spheroid cultures identifies novel regulators of lumen formation.
Li-Ting Wang, Marie-Ève Proulx, Anne D Kim, Virginie Lelarge, Luke McCaffrey

Sci Rep· November 2021

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A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding.
Jason Ear, Amer Ali Abd El-Hafeez, Suchismita Roy, Tony Ngo, Navin Rajapakse, Luke McCaffrey

J Biol Chem· September 2021

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CD13 orients the apical-basal polarity axis necessary for lumen formation.
Li-Ting Wang, Abira Rajah, Claire M Brown, Luke McCaffrey

Nat Commun· August 2021

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Architectural control of metabolic plasticity in epithelial cancer cells.
Maia Al-Masri, Karina Paliotti, Raymond Tran, Ruba Halaoui, Virginie Lelarge, Luke McCaffrey

Commun Biol· March 2021

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CCDC88B is required for mobility and inflammatory functions of dendritic cells.
Jean-Frederic Olivier, Nassima Fodil, Sara Al Habyan, Angelica Gopal, Patricio Artusa, Luke McCaffrey

J Leukoc Biol· December 2020

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Mapping cellular-scale internal mechanics in 3D tissues with thermally responsive hydrogel probes.
Stephanie Mok, Sara Al Habyan, Charles Ledoux, Wontae Lee, Katherine N MacDonald, Luke McCaffrey

Nat Commun· September 2020

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Genetic alterations of epithelial polarity genes are associated with loss of polarity in invasive breast cancer.
Rachel Catterall, Virginie Lelarge, Luke McCaffrey

Int J Cancer· March 2020

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Girdin is a component of the lateral polarity protein network restricting cell dissemination.
Cornélia Biehler, Li-Ting Wang, Myriam Sévigny, Alexandra Jetté, Clémence L Gamblin, Luke McCaffrey

PLoS Genet· March 2020

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Numb regulates cell tension required for mammary duct elongation.
Sudipa June Chatterjee, Ruba Halaoui, Rebecca Catherine Deagle, Carlis Rejon, Luke McCaffrey

Biol Open· May 2019

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MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma .
Qianyu Guo, Vivian Z Li, Jessica N Nichol, Fan Huang, William Yang, Luke McCaffrey

Cancer Res· April 2019

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Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures.
Wontae Lee, Nikita Kalashnikov, Stephanie Mok, Ruba Halaoui, Elena Kuzmin, Luke McCaffrey

Nat Commun· January 2019

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Multicellular detachment generates metastatic spheroids during intra-abdominal dissemination in epithelial ovarian cancer.
Sara Al Habyan, Christina Kalos, Joseph Szymborski, Luke McCaffrey

Oncogene· September 2018

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Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration.
Hannah Guak, Sara Al Habyan, Eric H Ma, Haya Aldossary, Maia Al-Masri, Luke M McCaffrey

Nat Commun· June 2018

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Progressive polarity loss and luminal collapse disrupt tissue organization in carcinoma.
Ruba Halaoui, Carlis Rejon, Sudipa June Chatterjee, Joseph Szymborski, Sarkis Meterissian, Luke McCaffrey

Genes Dev· August 2017

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CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair.
Khalid Hilmi, Maïka Jangal, Maud Marques, Tiejun Zhao, Amine Saad, Luke McCaffrey

Sci Adv· May 2017

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