Publications by authors named "Tony Ngo"

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RNA isoform diversity, splicing variants, and switching in single cells of the Alzheimer's disease brain.
Anis Shahnaee, Christine S Liu, Tony Ngo, Carter R Palmer, Derya Ziomek

Res Sq· September 2025

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RNA Isoform Diversity in Human Neurodegenerative Diseases.
Christine S Liu, Chris Park, Tony Ngo, Janani Saikumar, Carter R Palmer

eNeuro· December 2024

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The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors.
Stephen P H Alexander, Arthur Christopoulos, Anthony P Davenport, Eamonn Kelly, Alistair A Mathie, Marvin Gershengorn, Tony Ngo

Br J Pharmacol· October 2023

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A circuit for secretion-coupled cellular autonomy in multicellular eukaryotic cells.
Lingxia Qiao, Saptarshi Sinha, Amer Ali Abd El-Hafeez, I-Chung Lo, Krishna K Midde, Tony Ngo

Mol Syst Biol· April 2023

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Ponesimod inhibits astrocyte-mediated neuroinflammation and protects against cingulum demyelination via S1P -selective modulation.
Yasuyuki Kihara, Deepa Jonnalagadda, Yunjiao Zhu, Manisha Ray, Tony Ngo

FASEB J· February 2022

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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.
Stephen Ph Alexander, Arthur Christopoulos, Anthony P Davenport, Eamonn Kelly, Alistair Mathie, Marvin Gershengorn, Tony Ngo

Br J Pharmacol· October 2021

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A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding.
Jason Ear, Amer Ali Abd El-Hafeez, Suchismita Roy, Tony Ngo, Navin Rajapakse

J Biol Chem· September 2021

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Orphan receptor GPR37L1 remains unliganded.
Tony Ngo, Brendan P Wilkins, Sean S So, Peter Keov, Kirti K Chahal

Nat Chem Biol· April 2021

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Retraction Note: Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.
Tony Ngo, Andrey V Ilatovskiy, Alastair G Stewart, James L J Coleman, Fiona M McRobb

Nat Chem Biol· April 2021

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Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi.
Nicholas A Kalogriopoulos, Inmaculada Lopez-Sanchez, Changsheng Lin, Tony Ngo, Krishna K Midde

Proc Natl Acad Sci U S A· November 2020

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The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases.
James L J Coleman, Tony Ngo, Rhyll E Smythe, Andrew J Cleave, Nicole M Jones

Sci Rep· November 2020

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Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis.
Bryan S Stephens, Tony Ngo, Irina Kufareva, Tracy M Handel

Sci Signal· July 2020

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Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity.
Tony Ngo, Bryan S Stephens, Martin Gustavsson, Lauren G Holden, Ruben Abagyan

PLoS Biol· April 2020

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Structural basis for GPCR-independent activation of heterotrimeric Gi proteins.
Nicholas A Kalogriopoulos, Steven D Rees, Tony Ngo, Noah J Kopcho, Andrey V Ilatovskiy

Proc Natl Acad Sci U S A· August 2019

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Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control.
James L J Coleman, Margaret A Mouat, Jianxin Wu, Nikola Jancovski, Jaspreet K Bassi, Tony Ngo

Biol Sex Differ· April 2018

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Analysis of drug binding pockets and repurposing opportunities for twelve essential enzymes of ESKAPE pathogens.
Sadia Naz, Tony Ngo, Umar Farooq, Ruben Abagyan

PeerJ· September 2017

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The G protein-coupled receptor N-terminus and receptor signalling: N-tering a new era.
James L J Coleman, Tony Ngo, Nicola J Smith

Cell Signal· May 2017

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Orphan receptor ligand discovery by pickpocketing pharmacological neighbors.
Tony Ngo, Andrey V Ilatovskiy, Alastair G Stewart, James L J Coleman, Fiona M McRobb

Nat Chem Biol· February 2017

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Identifying ligands at orphan GPCRs: current status using structure-based approaches.
Tony Ngo, Irina Kufareva, James Lj Coleman, Robert M Graham, Ruben Abagyan

Br J Pharmacol· October 2016

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Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity.
James L J Coleman, Tony Ngo, Johannes Schmidt, Nadine Mrad, Chu Kong Liew

Sci Signal· April 2016

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Using constitutive activity to define appropriate high-throughput screening assays for orphan g protein-coupled receptors.
Tony Ngo, James L J Coleman, Nicola J Smith

Methods Mol Biol· September 2015

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Rapid Knockout and Reporter Mouse Line Generation and Breeding Colony Establishment Using EUCOMM Conditional-Ready Embryonic Stem Cells: A Case Study.
James L J Coleman, Karen Brennan, Tony Ngo, Poornima Balaji, Robert M Graham

Front Endocrinol (Lausanne)· July 2015

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5-HT1A receptor pharmacophores to screen for off-target activity of α1-adrenoceptor antagonists.
Tony Ngo, Timothy J Nicholas, Junli Chen, Angela M Finch, Renate Griffith

J Comput Aided Mol Des· April 2013

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One-step purification of a functional, constitutively activated form of visual arrestin.
Li Huang, Xiang Mao, Najmoutin G Abdulaev, Tony Ngo, Wei Liu

Protein Expr Purif· March 2012

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Designing point mutants to detect structural coupling in a heterotrimeric G protein alpha-subunit by NMR spectroscopy.
Najmoutin G Abdulaev, Xiang Mao, Eva Ramon, Tony Ngo, Justyna Mysliwy

Photochem Photobiol· July 2009

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