Publications by authors named "Richard Lobb"

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Single Extracellular Vesicle Profiling to Define Brain Specific Traumatic Brain Injury Induced Neuro-Inflammation.
Zhen Zhang, Richard J Lobb, Rebecca E Lane, Xuan Vinh To, Xueming Niu

Small Methods· July 2025

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Glycan Profiling in Small Extracellular Vesicles with a SERS Microfluidic Biosensor Identifies Early Malignant Development in Lung Cancer.
Quan Zhou, Xueming Niu, Zhen Zhang, Kenneth O'Byrne, Arutha Kulasinghe, Richard J Lobb

Adv Sci (Weinh)· September 2024

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Analysis of secreted small extracellular vesicles from activated human microglial cell lines reveals distinct pro- and anti-inflammatory proteomic profiles.
Xueming Niu, Zhen Zhang, Quan Zhou, Alain Wuethrich, Richard Lobb

Proteomics· June 2024

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A mesoporous gold biosensor to investigate immune checkpoint protein heterogeneity in single lung cancer cells.
Emtiaz Ahmed, Mostafa Kamal Masud, Prathyusha Komatineni, Shuvashis Dey, Richard Lobb

Biosens Bioelectron· April 2024

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Tracking the EMT-like phenotype switching during targeted therapy in melanoma by analyzing extracellular vesicle phenotypes.
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J Lobb

Biosens Bioelectron· January 2024

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A universal reagent for detection of emerging diseases using bioengineered multifunctional yeast nanofragments.
Junrong Li, Christopher B Howard, Shuvashis Dey, Kym Lowry, David M Whiley, Richard J Lobb

Nat Nanotechnol· October 2023

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An epithelial-to-mesenchymal transition induced extracellular vesicle prognostic signature in non-small cell lung cancer.
Richard J Lobb, Kekoolani S Visan, Li-Ying Wu, Emma L Norris, Marcus L Hastie

Commun Biol· January 2023

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Digital Decoding of Single Extracellular Vesicle Phenotype Differentiates Early Malignant and Benign Lung Lesions.
Junrong Li, Abu A I Sina, Fiach Antaw, David Fielding, Andreas Möller, Richard Lobb

Adv Sci (Weinh)· November 2022

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Comparative analysis of tangential flow filtration and ultracentrifugation, both combined with subsequent size exclusion chromatography, for the isolation of small extracellular vesicles.
Kekoolani S Visan, Richard J Lobb, Sunyoung Ham, Luize G Lima, Carlos Palma

J Extracell Vesicles· September 2022

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Blood-Derived Extracellular Vesicle-Associated miR-3182 Detects Non-Small Cell Lung Cancer Patients.
Kekoolani S Visan, Richard J Lobb, Shu Wen Wen, Justin Bedo, Luize G Lima

Cancers (Basel)· January 2022

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Generation of Nanoyeast Single-Chain Variable Fragments as High-Avidity Biomaterials for Dengue Virus Detection.
Fahimeh Farokhinejad, Rebecca E Lane, Richard J Lobb, Selvakumar Edwardraja, Alain Wuethrich

ACS Biomater Sci Eng· December 2021

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Characterizing the Heterogeneity of Small Extracellular Vesicle Populations in Multiple Cancer Types an Ultrasensitive Chip.
Jing Wang, Alain Wuethrich, Richard J Lobb, Fiach Antaw, Abu Ali Ibn Sina

ACS Sens· September 2021

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Amplification-Free SARS-CoV-2 Detection Using Nanoyeast-scFv and Ultrasensitive Plasmonic Nanobox-Integrated Nanomixing Microassay.
Junrong Li, Alain Wuethrich, Selvakumar Edwardraja, Richard J Lobb, Simon Puttick

Anal Chem· July 2021

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Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution.
Luize G Lima, Sunyoung Ham, Hyunku Shin, Edna P Z Chai, Erica S H Lek, Richard J Lobb

Nat Commun· June 2021

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The evolving translational potential of small extracellular vesicles in cancer.
Andreas Möller, Richard J Lobb

Nat Rev Cancer· December 2020

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The role of exosomes in the promotion of epithelial-to-mesenchymal transition and metastasis.
Kekoolani S Visan, Richard J Lobb, Andreas Moller

Front Biosci (Landmark Ed)· March 2020

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Breast Cancer-Derived Exosomes Alter Macrophage Polarization gp130/STAT3 Signaling.
Sunyoung Ham, Luize G Lima, Edna Pei Zhi Chai, Alexandra Muller, Richard J Lobb

Front Immunol· July 2019

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Breast Cancer-Derived Exosomes Reflect the Cell-of-Origin Phenotype.
Shu Wen Wen, Luize G Lima, Richard J Lobb, Emma L Norris, Marcus L Hastie

Proteomics· April 2019

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Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer.
Adrian P Wiegmans, Jodi M Saunus, Sunyoung Ham, Richard Lobb, Jamie R Kutasovic

JCI Insight· February 2019

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The Interaction of Selenium with Chemotherapy and Radiation on Normal and Malignant Human Mononuclear Blood Cells.
Richard J Lobb, Gregory M Jacobson, Ray T Cursons, Michael B Jameson

Int J Mol Sci· October 2018

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Size Exclusion Chromatography: A Simple and Reliable Method for Exosome Purification.
Richard Lobb, Andreas Möller

Methods Mol Biol· May 2018

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Oncogenic transformation of lung cells results in distinct exosome protein profile similar to the cell of origin.
Richard J Lobb, Marcus L Hastie, Emma L Norris, Rosa van Amerongen, Jeffrey J Gorman

Proteomics· December 2017

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Exosomes derived from mesenchymal non-small cell lung cancer cells promote chemoresistance.
Richard J Lobb, Rosa van Amerongen, Adrian Wiegmans, Sunyoung Ham, Jill E Larsen

Int J Cancer· August 2017

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Exosomes: Key mediators of metastasis and pre-metastatic niche formation.
Richard J Lobb, Luize G Lima, Andreas Möller

Semin Cell Dev Biol· July 2017

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Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions.
Xiangju Wang, Ray Wilkinson, Katrina Kildey, Jeremy Potriquet, Jason Mulvenna, Richard J Lobb

J Extracell Vesicles· April 2017

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