Publications by authors named "Richard Spelman"

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An Increase in Male Recombination Rate With Age in Dairy Cattle Is Heritable and Polygenic.
Evelyn Jade, Mathew D Littlejohn, Katie Eketone, Richard J Spelman, Jessica Stapley

J Anim Breed Genet· January 2026

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Structural and epistatic regulatory variants cause hallmark white spotting in cattle.
Swati Jivanji, Emma Wilkinson, Lijing Tang, Kathryn M Tiplady, Anna Yeates, Richard J Spelman

Sci Adv· November 2025

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Sire association with intramammary infection and clinical mastitis in a Holstein-Friesian × Jersey crossbred pedigree herd.
S Jane Lacy-Hulbert, Sally-Anne Turner, Barbara Kuhn-Sherlock, John H Williamson, Richard J Spelman

J Dairy Res· November 2024

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A common regulatory haplotype doubles lactoferrin concentration in milk.
Thomas J Lopdell, Alexander J Trevarton, Janelle Moody, Claire Prowse-Wilkins, Sarah Knowles, Richard J Spelman

Genet Sel Evol· March 2024

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Comparison of the genetic characteristics of directly measured and Fourier-transform mid-infrared-predicted bovine milk fatty acids and proteins.
Kathryn M Tiplady, Thomas J Lopdell, Richard G Sherlock, Thomas J J Johnson, Richard J Spelman

J Dairy Sci· November 2022

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Screening for phenotypic outliers identifies an unusually low concentration of a β-lactoglobulin B protein isoform in bovine milk caused by a synonymous SNP.
Stephen R Davis, Hamish E Ward, Van Kelly, David Palmer, Alexandra E Ankersmit-Udy, Richard J Spelman

Genet Sel Evol· March 2022

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Non-additive QTL mapping of lactation traits in 124,000 cattle reveals novel recessive loci.
Edwardo G M Reynolds, Thomas Lopdell, Yu Wang, Kathryn M Tiplady, Chad S Harland, Richard J Spelman

Genet Sel Evol· January 2022

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Non-additive association analysis using proxy phenotypes identifies novel cattle syndromes.
Edwardo G M Reynolds, Catherine Neeley, Thomas J Lopdell, Michael Keehan, Keren Dittmer, Richard J Spelman

Nat Genet· July 2021

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Sequence-based genome-wide association study of individual milk mid-infrared wavenumbers in mixed-breed dairy cattle.
Kathryn M Tiplady, Thomas J Lopdell, Edwardo Reynolds, Richard G Sherlock, Michael Keehan, Richard J Spelman

Genet Sel Evol· July 2021

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Genetic architecture of individual variation in recombination rate on the X chromosome in cattle.
Junjie Zhang, Naveen Kumar Kadri, Erik Mullaart, Richard Spelman, Sébastien Fritz

Heredity (Edinb)· November 2020

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A new mechanism for a familiar mutation - bovine DGAT1 K232A modulates gene expression through multi-junction exon splice enhancement.
Tania Fink, Thomas J Lopdell, Kathryn Tiplady, Renee Handley, Thomas J J Johnson, Richard J Spelman

BMC Genomics· August 2020

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Genome-wide association analysis reveals QTL and candidate mutations involved in white spotting in cattle.
Swati Jivanji, Gemma Worth, Thomas J Lopdell, Anna Yeates, Christine Couldrey, Richard Spelman

Genet Sel Evol· November 2019

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Multiple QTL underlie milk phenotypes at the CSF2RB locus.
Thomas J Lopdell, Kathryn Tiplady, Christine Couldrey, Thomas J J Johnson, Michael Keehan, Richard J Spelman

Genet Sel Evol· January 2019

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Identification of an immune modulation locus utilising a bovine mammary gland infection challenge model.
Mathew D Littlejohn, Sally-Anne Turner, Caroline G Walker, Sarah D Berry, Kathryn Tiplady, Richard J Spelman

J Dairy Res· May 2018

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DNA and RNA-sequence based GWAS highlights membrane-transport genes as key modulators of milk lactose content.
Thomas J Lopdell, Kathryn Tiplady, Maksim Struchalin, Thomas J J Johnson, Michael Keehan, Richard J Spelman

BMC Genomics· December 2017

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Functional confirmation of PLAG1 as the candidate causative gene underlying major pleiotropic effects on body weight and milk characteristics.
Tania Fink, Kathryn Tiplady, Thomas Lopdell, Thomas Johnson, Russell G Snell, Richard J Spelman

Sci Rep· March 2017

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Coding and noncoding variants in HFM1, MLH3, MSH4, MSH5, RNF212, and RNF212B affect recombination rate in cattle.
Naveen Kumar Kadri, Chad Harland, Pierre Faux, Nadine Cambisano, Latifa Karim, Richard Spelman

Genome Res· October 2016

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NGS-based reverse genetic screen for common embryonic lethal mutations compromising fertility in livestock.
Carole Charlier, Wanbo Li, Chad Harland, Mathew Littlejohn, Wouter Coppieters, Richard Spelman

Genome Res· October 2016

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Sequence-based Association Analysis Reveals an MGST1 eQTL with Pleiotropic Effects on Bovine Milk Composition.
Mathew D Littlejohn, Kathryn Tiplady, Tania A Fink, Klaus Lehnert, Thomas Lopdell, Richard J Spelman

Sci Rep· May 2016

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Rapid, quantitative analysis of 3'- and 6'-sialyllactose in milk by flow-injection analysis-mass spectrometry: screening of milks for naturally elevated sialyllactose concentration.
Van Kelly, Steve Davis, Sarah Berry, Janine Melis, Richard Spelman

J Dairy Sci· April 2016

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Phenotypic population screen identifies a new mutation in bovine DGAT1 responsible for unsaturated milk fat.
Klaus Lehnert, Hamish Ward, Sarah D Berry, Alex Ankersmit-Udy, Alayna Burrett, Richard J Spelman

Sci Rep· February 2015

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Functionally reciprocal mutations of the prolactin signalling pathway define hairy and slick cattle.
Mathew D Littlejohn, Kristen M Henty, Kathryn Tiplady, Thomas Johnson, Chad Harland, Richard J Spelman

Nat Commun· December 2014

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Expression variants of the lipogenic AGPAT6 gene affect diverse milk composition phenotypes in Bos taurus.
Mathew D Littlejohn, Kathryn Tiplady, Thomas Lopdell, Tania A Law, Andrew Scott, Richard J Spelman

PLoS One· October 2014

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Estimation of genetic and crossbreeding parameters of fatty acid concentrations in milk fat predicted by mid-infrared spectroscopy in New Zealand dairy cattle.
Nicolas Lopez-Villalobos, Richard J Spelman, Janine Melis, Stephen R Davis, Sarah D Berry

J Dairy Res· August 2014

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A triad of highly divergent polymeric immunoglobulin receptor (PIGR) haplotypes with major effect on IgA concentration in bovine milk.
Sarah Berry, Wouter Coppieters, Stephen Davis, Alayna Burrett, Natalie Thomas, Richard Spelman

PLoS One· December 2013

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