Publications by authors named "Robert D Simpson"

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Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility.
Lanqi Jia, Robert D Simpson, Jing Yuan, Zhenrong Xu, Wei Zhao

ACS Med Chem Lett· October 2011

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Biphenyl/diphenyl ether renin inhibitors: filling the S1 pocket of renin via the S3 pocket.
Jing Yuan, Robert D Simpson, Wei Zhao, Colin M Tice, Zhenrong Xu

Bioorg Med Chem Lett· August 2011

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Spirocyclic ureas: orally bioavailable 11 beta-HSD1 inhibitors identified by computer-aided drug design.
Colin M Tice, Wei Zhao, Zhenrong Xu, Salvacion T Cacatian, Robert D Simpson

Bioorg Med Chem Lett· February 2010

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Optimization of orally bioavailable alkyl amine renin inhibitors.
Zhenrong Xu, Salvacion Cacatian, Jing Yuan, Robert D Simpson, Lanqi Jia

Bioorg Med Chem Lett· January 2010

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Design and optimization of renin inhibitors: Orally bioavailable alkyl amines.
Colin M Tice, Zhenrong Xu, Jing Yuan, Robert D Simpson, Salvacion T Cacatian

Bioorg Med Chem Lett· July 2009

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Efficient large-scale synthesis of BILN 2061, a potent HCV protease inhibitor, by a convergent approach based on ring-closing metathesis.
Nathan K Yee, Vittorio Farina, Ioannis N Houpis, Nizar Haddad, Rogelio P Frutos, Robert D Simpson

J Org Chem· September 2006

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Electronic control of chiral quaternary center creation in the intramolecular asymmetric heck reaction.
Carl A Busacca, Danja Grossbach, Scot J Campbell, Yong Dong, Magnus C Eriksson, Robert D Simpson

J Org Chem· August 2004

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