Publications by authors named "Robert Keyes"

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Reutericyclin, a specialized metabolite of , mitigates risperidone-induced weight gain in mice.
Fatima A Aboulalazm, Alexis B Kazen, Orlando deLeon, Susanne Müller, Fatima L Saravia, Robert F Keyes

Gut Microbes· December 2025

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Polybromo‑1 Bromodomain Inhibitor Selectivity Is Mediated by a Unique Ligand-Binding Pocket.
Raymundo Nuñez, Karina L Bursch, Savannah J Makowski, Mingguang Xue, Kira A Cozzolino, Robert F Keyes

ACS Med Chem Lett· October 2025

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The TRIM33 Bromodomain Recognizes Histone Lysine Lactylation.
Raymundo Nuñez, Paul F W Sidlowski, Erica A Steen, Sarah L Wynia-Smith, Daniel J Sprague, Robert F Keyes

ACS Chem Biol· December 2024

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Lipid Trolling to Optimize A Adenosine Receptor-Positive Allosteric Modulators (PAMs).
Balaram Pradhan, Matteo Pavan, Courtney L Fisher, Veronica Salmaso, Tina C Wan, Robert F Keyes

J Med Chem· July 2024

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Extrahelical Binding Site for a 1-Imidazo[4,5-c]quinolin-4-amine A Adenosine Receptor Positive Allosteric Modulator on Helix 8 and Distal Portions of Transmembrane Domains 1 and 7.
Courtney L Fisher, Matteo Pavan, Veronica Salmaso, Robert F Keyes, Tina C Wan

Mol Pharmacol· February 2024

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Synthesis of fluorinated triphenylphosphonium analogs that improve cancer cell selectivity and in vivo detection.
Robert F Keyes, Donna McAllister, Michael B Dwinell, Brian C Smith

STAR Protoc· September 2023

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Sulfenylation links oxidative stress to protein disulfide isomerase oxidase activity and thrombus formation.
Moua Yang, Joyce Chiu, Christina Scartelli, Nathan Ponzar, Sachin Patel, Robert F Keyes

J Thromb Haemost· August 2023

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Harnessing the Noncanonical Keap1-Nrf2 Pathway for Human Cytomegalovirus Control.
Ayan K Ghosh, Yu-Pin Su, Michael Forman, Robert F Keyes, Brian C Smith

J Virol· April 2023

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Fluorinated triphenylphosphonium analogs improve cell selectivity and detection of mito-metformin.
Mahmoud AbuEid, Robert F Keyes, Donna McAllister, Francis Peterson, Ishaque Pulikkal Kadamberi

iScience· December 2022

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Characterization of Dual-Acting A Adenosine Receptor Positive Allosteric Modulators That Preferentially Enhance Adenosine-Induced Gα and Gα Isoprotein Activation.
Courtney L Fisher, Lucas B Fallot, Tina C Wan, Robert F Keyes, R Rama Suresh

ACS Pharmacol Transl Sci· August 2022

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The Synthesis and Anti-Cytomegalovirus Activity of Piperidine-4-Carboxamides.
Xin Guo, Ayan Kumar Ghosh, Robert F Keyes, Francis Peterson, Michael Forman

Viruses· January 2022

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Validation and Characterization of Five Distinct Novel Inhibitors of Human Cytomegalovirus.
Arun Kapoor, Ayan K Ghosh, Michael Forman, Xin Hu, Wenjuan Ye, Robert F Keyes

J Med Chem· April 2020

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Canadian Association of Emergency Physicians sepsis treatment checklist: optimizing sepsis care in Canadian emergency departments.
Dennis Djogovic, Robert Green, Robert Keyes, Sara Gray, Robert Stenstrom

CJEM· January 2012

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Best evidence in critical care medicine. Vasopressin in septic shock: pressing questions remain.
Robert Keyes, Peter G Brindley

Can J Anaesth· January 2009

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Early diagnosis of acute kidney injury in critically ill patients.
Robert Keyes, Sean M Bagshaw

Expert Rev Mol Diagn· July 2008

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T
The synthesis and structure-activity relationship studies of selective acetyl-CoA carboxylase inhibitors containing 4-(thiazol-5-yl)but-3-yn-2-amino motif: polar region modifications.
Xiangdong Xu, Moshe Weitzberg, Robert F Keyes, Qun Li, Rongqi Wang

Bioorg Med Chem Lett· March 2007

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N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy derivatives as acetyl-coA carboxylase inhibitors--improvement of cardiovascular and neurological liabilities via structural modifications.
Yu Gui Gu, Moshe Weitzberg, Richard F Clark, Xiangdong Xu, Qun Li, Robert F Keyes

J Med Chem· March 2007

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An unusual intramolecular hetero-Diels-Alder cycloaddition.
Eric J Stoner, Michael S Allen, Alan C Christesen, Rodger F Henry, L Steven Hollis, Robert Keyes

J Org Chem· April 2005

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Short and efficient synthesis of a vinyl-substituted tricyclic erythromycin derivative.
Robert F Keyes, Justin J Carter, Xiaolin Zhang, Zhenkun Ma

Org Lett· March 2005

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Synthesis and antibacterial activity of 6-O-arylbutynyl ketolides with improved activity against some key erythromycin-resistant pathogens.
Robert F Keyes, Justin J Carter, Erika E Englund, Melissa M Daly, Greg G Stone

J Med Chem· May 2003

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Carotid artery dissection as a possible severe complication of pertussis in an adult: clinical case report and review.
Danuta M Skowronski, Jane A Buxton, Morris Hestrin, Robert D Keyes, Kevin Lynch

Clin Infect Dis· January 2003

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Lighting up logic.
Robert W Keyes

Nature· March 1993

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