Publications by authors named "Robert MacLeod"

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Are drivers recurring or ephemeral? observations from serial mapping of persistent atrial fibrillation.
Bram Hunt, Eugene Kwan, Eric Paccione, Benjamin Orkild, Kyoichiro Yazaki, Robert S MacLeod

Europace· November 2024

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Inhibition of MER proto-oncogene tyrosine kinase by an antisense oligonucleotide enhances treatment efficacy of immunoradiotherapy.
Yun Hu, Alexey Revenko, Hampartsoum Barsoumian, Genevieve Bertolet, Natalie Wall Fowlkes, Robert MacLeod

J Exp Clin Cancer Res· March 2024

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Transfer Learning for Improved Classification of Drivers in Atrial Fibrillation.
Bram Hunt, Eugene Kwan, Tolga Tasdizen, Jake Bergquist, Matthias Lange, Robert S MacLeod

Comput Cardiol (2010)· October 2023

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Emerging ECG methods for acute coronary syndrome detection: Recommendations & future opportunities.
Salah Al-Zaiti, Robert Macleod, Peter Van Dam, Stephen W Smith, Yochai Birnbaum

J Electrocardiol· December 2022

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The androgen receptor is a therapeutic target in desmoplastic small round cell sarcoma.
Salah-Eddine Lamhamedi-Cherradi, Mayinuer Maitituoheti, Brian A Menegaz, Sandhya Krishnan, Amelia M Vetter, A Robert MacLeod

Nat Commun· June 2022

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Corrigendum to: 'Telomere length is key to hepatocellular carcinoma diversity and telomerase addiction is an actionable therapeutic target' [J Hepatol 2021 (74) 1155-1166].
Massih Ningarhari, Stefano Caruso, Théo Z Hirsch, Quentin Bayard, Andrea Franconi, A Robert MacLeod

J Hepatol· May 2022

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Plasma Kallikrein Contributes to Intracerebral Hemorrhage and Hypertension in Stroke-Prone Spontaneously Hypertensive Rats.
Jian Guan, Allen C Clermont, Loc-Duyen Pham, Tuna Ustunkaya, Alexey S Revenko, A Robert MacLeod

Transl Stroke Res· April 2022

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Direct targeting of FOXP3 in Tregs with AZD8701, a novel antisense oligonucleotide to relieve immunosuppression in cancer.
Alexey Revenko, Larissa S Carnevalli, Charles Sinclair, Ben Johnson, Alison Peter, A Robert MacLeod

J Immunother Cancer· April 2022

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Inhibition of Prekallikrein for Hereditary Angioedema.
Lauré M Fijen, Marc A Riedl, Laura Bordone, Jonathan A Bernstein, Jason Raasch, A Robert MacLeod

N Engl J Med· March 2022

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Specific targeting of the KRAS mutational landscape in myeloma as a tool to unveil the elicited antitumor activity.
Antonio Sacco, Cinzia Federico, Katia Todoerti, Bachisio Ziccheddu, Valentina Palermo, A Robert Macleod

Blood· November 2021

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Antisense oligonucleotide activity in tumour cells is influenced by intracellular LBPA distribution and extracellular vesicle recycling.
Alexander N Kapustin, Paul Davey, David Longmire, Carl Matthews, Emily Linnane, A Robert MacLeod

Commun Biol· November 2021

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Sensitive intranuclear flow cytometric quantification of IRF4 protein in multiple myeloma and normal human hematopoietic cells.
Ashni A Vora, Phoebe K Mondala, Caitlin Costello, A Robert MacLeod, Leslie A Crews

STAR Protoc· June 2021

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Telomere length is key to hepatocellular carcinoma diversity and telomerase addiction is an actionable therapeutic target.
Massih Ningarhari, Stefano Caruso, Théo Z Hirsch, Quentin Bayard, Andrea Franconi, A Robert MacLeod

J Hepatol· May 2021

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Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption.
Phoebe K Mondala, Ashni A Vora, Tianyuan Zhou, Elisa Lazzari, Luisa Ladel, A Robert MacLeod

Cell Stem Cell· April 2021

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Correction to: LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma.
Yan Xu, Yuan Li, Jiankang Jin, Guangchun Han, Chengcao Sun, A Robert MacLeod

Mol Cancer· March 2021

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LncRNA PVT1 Is a Poor Prognosticator and Can Be Targeted by PVT1 Antisense Oligos in Gastric Adenocarcinoma.
Yuan Li, Shumei Song, Melissa Pool Pizzi, Guangchun Han, Ailing W Scott, Robert MacLeod

Cancers (Basel)· October 2020

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Identifying locations of re-entrant drivers from patient-specific distribution of fibrosis in the left atrium.
Aditi Roy, Marta Varela, Henry Chubb, Robert MacLeod, Jules C Hancox

PLoS Comput Biol· September 2020

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Kininogen supports inflammation and bacterial spreading during Streptococccus Pyogenes Sepsis.
Juliane Köhler, Claudia Maletzki, Dirk Koczan, Marcus Frank, Armin Springer, A Robert MacLeod

EBioMedicine· August 2020

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Interferon regulatory factor 4 as a therapeutic target in adult T-cell leukemia lymphoma.
Daniel A Rauch, Sydney L Olson, John C Harding, Hemalatha Sundaramoorthi, Youngsoo Kim, A Robert MacLeod

Retrovirology· August 2020

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Antisense oligonucleotide targeting of thrombopoietin represents a novel platelet depletion method to assess the immunomodulatory role of platelets.
Tessa J Barrett, Benjamin G Wu, Alexey S Revenko, A Robert MacLeod, Leopoldo N Segal

J Thromb Haemost· July 2020

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The contact system proteases play disparate roles in streptococcal sepsis.
Juliane Köhler, Claudia Maletzki, Dirk Koczan, Marcus Frank, Carolin Trepesch, A Robert Macleod

Haematologica· May 2020

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A novel and translational role for autophagy in antisense oligonucleotide trafficking and activity.
Joseph Ochaba, Andrew F Powers, Kaitlyn A Tremble, Sarah Greenlee, Noah M Post, A Robert MacLeod

Nucleic Acids Res· December 2019

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The Effective Contact Force to Minimize Edema Relative to Chronic Lesion Formation During Radiofrequency Ablation in Ventricular Wall.
Kennosuke Yamashita, Elyar Ghafoori, Josh Silvernagel, John Ashton, Derek J Dosdall, Robert MacLeod

Int Heart J· November 2019

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LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma.
Yan Xu, Yuan Li, Jiankang Jin, Guangchun Han, Chengcao Sun, A Robert MacLeod

Mol Cancer· October 2019

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Targeting castration-resistant prostate cancer with androgen receptor antisense oligonucleotide therapy.
Marco A De Velasco, Yurie Kura, Kazuko Sakai, Yuji Hatanaka, Barry R Davies, A Robert MacLeod

JCI Insight· September 2019

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