Publications by authors named "Robert Plumb"

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Mass Spectrometry-Based Quantification of Proteins and Post-Translational Modifications in Dried Blood: Longitudinal Sampling of Patients With Sepsis in Tanzania.
Matthew W Foster, Timothy J McMahon, James S Ngocho, Asia H Kipengele, Marlene Violette, Robert S Plumb

Proteomics· December 2025

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Adaptive Modeling of Tandem Mass Spectrometry Data: Creation of the METLIN 960K MRM Database.
Aries Aisporna, Bill Webb, Winnie Uritboonthai, Linh Hoang, Elizabeth M Billings, Robert Plumb

Anal Chem· November 2025

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An investigation of the plasma and urinary metabolite profiles of the hepatotoxin methapyrilene in the male Wistar rat.
Robert S Plumb, Steven K Lai, Lee A Gethings, Robert Trengove, Peter Hancock

J Pharm Biomed Anal· October 2025

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Development and validation of a streamlined workflow for proteomic analysis of proteins and post-translational modifications from dried blood.
Matthew W Foster, Youwei Chen, Marlene Violette, Michael T Forrester, J Scott Mellors, Robert S Plumb

bioRxiv· September 2025

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A HILIC-IM-MS-Based Pharmacometabodynamic Study of the Effects of Orally Administered Gefitinib on the Polar Urinary Metabolic Phenotypes of C57Bl6 Mice.
Adam King, Lee A Gethings, Robert S Plumb, Ian D Wilson

J Sep Sci· May 2025

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Mass spectrometry-based quantification of proteins and post-translational modifications in dried blood: longitudinal sampling of patients with sepsis in Tanzania.
Matthew W Foster, Timothy J McMahon, James S Ngocho, Asia H Kipengele, Marlene Violette, Robert S Plumb

bioRxiv· April 2025

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Microbore-based vacuum jacketed liquid chromatography for fast, efficient and sustainable high throughput bioanalysis.
Ian D Wilson, Paul D Rainville, Lee A Gethings, Peter Hancock, Robert Trengove, Robert S Plumb

J Chromatogr A· October 2024

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Detection of pharmacolipidodynamic effects following the intravenous and oral administration of gefitinib to C57Bl/6JRj mice by rapid UHPLC-MS analysis of plasma.
Robert S Plumb, Lee A Gethings, Giorgis Isaac, Nyasha C Munjoma, Ian D Wilson

Sci Rep· July 2024

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Development of a single mobile phase for LC-IM-MS-based discovery lipidomics and metabolic phenotyping: Application to methapyrilene hepatotoxicity in the rat.
Ian D Wilson, Corey Broeckling, Lee A Gethings, Nyasha C Munjoma, Robert Trengove, Robert S Plumb

J Chromatogr A· January 2024

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Increasing coverage of the urinary polar metabolome using ultra high-performance hydrophobic interaction liquid chromatography combined with linear and cyclic travelling wave ion mobility and mass spectrometry.
Adam King, Lee A Gethings, Johannes P C Vissers, Robert S Plumb, Ian D Wilson

J Chromatogr A· January 2024

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The rapid separation and characterization of sulfates of tyrosine and its metabolites in reaction mixtures and human urine using a cyclic ion mobility device and mass spectrometry.
Adam M King, Ian D Wilson, Robert S Plumb, Lee A Gethings, Robert Trengove

J Chromatogr A· January 2024

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METLIN-CCS: an ion mobility spectrometry collision cross section database.
Erin S Baker, Corey Hoang, Winnie Uritboonthai, Heino M Heyman, Brian Pratt, Robert Plumb

Nat Methods· December 2023

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Multi-omic diagnostics of prostate cancer in the presence of benign prostatic hyperplasia.
Matt Spick, Ammara Muazzam, Hardev Pandha, Agnieszka Michael, Lee A Gethings, Robert S Plumb

Heliyon· December 2023

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Understanding mobile phase buffer composition and chemical structure effects on electrospray ionization mass spectrometry response.
Allison Brookhart, Mahika Arora, Michael McCullagh, Ian D Wilson, Robert S Plumb

J Chromatogr A· May 2023

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Enhanced chromatographic efficiency obtained with vacuum jacketed columns facilitates the rapid UHPLC/MS/MS-based analysis of fasiglifam in rat plasma.
Nikunj Tanna, Robert S Plumb, Billy J Molloy, Paul D Rainville, Ian D Wilson

Talanta· March 2023

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Ensuring Fact-Based Metabolite Identification in Liquid Chromatography-Mass Spectrometry-Based Metabolomics.
Georgios Theodoridis, Helen Gika, Daniel Raftery, Royston Goodacre, Robert S Plumb

Anal Chem· February 2023

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Investigation of the pharmacokinetics and metabolic fate of Fasiglifam (TAK-875) in male and female rats following oral and intravenous administration.
Billy J Molloy, Adam King, Lee A Gethings, Robert S Plumb, Russell J Mortishire-Smith

Xenobiotica· February 2023

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A Novel Blood Proteomic Signature for Prostate Cancer.
Ammara Muazzam, Matt Spick, Olivier N F Cexus, Bethany Geary, Fowz Azhar, Robert S Plumb

Cancers (Basel)· February 2023

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High Throughput LC-MS Platform for Large Scale Screening of Bioactive Polar Lipids in Human Plasma and Serum.
Nyasha Munjoma, Giorgis Isaac, Ammara Muazzam, Olivier Cexus, Fowz Azhar, Robert S Plumb

J Proteome Res· November 2022

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Access to the Phospho-proteome via the Mitigation of Peptide-Metal Interactions.
Christopher J Hughes, Lee A Gethings, Ian D Wilson, Robert S Plumb

J Chromatogr A· June 2022

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High performance Reversed-Phase Thin-Layer Chromatography-Desorption electrospray ionisation - time of flight high resolution mass spectrometric detection and imaging (HPTLC/DESI/ToFMS) of phytoecdysteroids.
Emmanuelle Claude, Rene Lafont, Robert S Plumb, Ian D Wilson

J Chromatogr B Analyt Technol Biomed Life Sci· June 2022

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Application of hybrid surface technology for improving sensitivity and peak shape of phosphorylated lipids such as phosphatidic acid and phosphatidylserine.
Giorgis Isaac, Ian D Wilson, Robert S Plumb

J Chromatogr A· April 2022

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High Throughput UHPLC-MS-Based Lipidomics Using Vacuum Jacketed Columns.
Robert S Plumb, Giorgis Isaac, Paul D Rainville, Jason Hill, Lee A Gethings

J Proteome Res· March 2022

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Non-targeted Lipidomics Using a Robust and Reproducible Lipid Separation Using UPLC with Charged Surface Hybrid Technology and High-Resolution Mass Spectrometry.
Giorgis Isaac, Vladimir Shulaev, Robert S Plumb

Methods Mol Biol· December 2021

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High-Throughput UHPLC/MS/MS-Based Metabolic Profiling Using a Vacuum Jacketed Column.
Robert S Plumb, Thomas McDonald, Paul D Rainville, Jason Hill, Lee A Gethings

Anal Chem· August 2021

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