Publications by authors named "Robert Pulz"

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Next generation Bruton's tyrosine kinase inhibitors - characterization of in vitro potency and selectivity.
Robert Pulz, Daniela Angst, Bruno Cenni

Eur J Pharmacol· September 2025

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A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent manner.
Aude Sylvain, Natacha Stoehr, Fupeng Ma, Artiom Cernijenko, Martin Schröder, Robert Pulz

Cell Chem Biol· July 2025

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Design and Synthesis of Inhibitors of the E3 Ligase SMAD Specific E3 Ubiquitin Protein Ligase 1 as a Treatment for Lung Remodeling in Pulmonary Arterial Hypertension.
Duncan E Shaw, Nichola Smith, Rene Beerli, Simona Cotesta, Pier-Luca D'Alessandro, Robert Pulz

J Med Chem· June 2023

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Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
Daniela Angst, François Gessier, Philipp Janser, Anna Vulpetti, Rudolf Wälchli, Robert Pulz

J Med Chem· May 2020

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Design of Potent and Selective Covalent Inhibitors of Bruton's Tyrosine Kinase Targeting an Inactive Conformation.
Robert Pulz, Daniela Angst, Janet Dawson, Francois Gessier, Sascha Gutmann

ACS Med Chem Lett· October 2019

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New polyhydroxylated pyrrolidines derived from enantiopure 3,6-dihydro-2H-1,2-oxazines.
Robert Pulz, Ahmed Al-Harrasi, Hans-Ulrich Reissig

Org Lett· July 2002

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