Publications by authors named "Robert Solinga"

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Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase.
Jessica A Wales, Cheng-Yu Chen, Linda Breci, Andrzej Weichsel, Sylvie G Bernier, Robert Solinga

J Biol Chem· February 2018

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Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017.
G. Todd Milne, , Peter Sandner, Kathleen A. Lincoln, Paul C. Harrison, Robert Solinga

BMC Pharmacol Toxicol· October 2017

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Linaclotide activates guanylate cyclase-C/cGMP/protein kinase-II-dependent trafficking of CFTR in the intestine.
Md Kaimul Ahsan, Boris Tchernychev, Marco M Kessler, Robert M Solinga, David Arthur

Physiol Rep· June 2017

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MRP4 Modulation of the Guanylate Cyclase-C/cGMP Pathway: Effects on Linaclotide-Induced Electrolyte Secretion and cGMP Efflux.
Boris Tchernychev, Pei Ge, Marco M Kessler, Robert M Solinga, Derek Wachtel

J Pharmacol Exp Ther· October 2015

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Activation of guanylate cyclase-C attenuates stretch responses and sensitization of mouse colorectal afferents.
Bin Feng, Michael E Kiyatkin, Jun-Ho La, Pei Ge, Robert Solinga

J Neurosci· June 2013

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Pharmacologic properties, metabolism, and disposition of linaclotide, a novel therapeutic peptide approved for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation.
Robert W Busby, Marco M Kessler, Wilmin P Bartolini, Alexander P Bryant, Gerhard Hannig, Robert M Solinga

J Pharmacol Exp Ther· January 2013

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Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit.
Robert W Busby, Alexander P Bryant, Wilmin P Bartolini, Etchell A Cordero, Gerhard Hannig, Robert M Solinga

Eur J Pharmacol· December 2010

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Characterization of the structure and biological functions of a capsular polysaccharide produced by Staphylococcus saprophyticus.
Sunny Park, Kathryn A Kelley, Evgeny Vinogradov, Robert Solinga, Christopher Weidenmaier

J Bacteriol· September 2010

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Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract.
Alexander P Bryant, Robert W Busby, Wilmin P Bartolini, Etchell A Cordero, Gerhard Hannig, Robert M Solinga

Life Sci· May 2010

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The natriuretic peptide uroguanylin elicits physiologic actions through 2 distinct topoisomers.
Nicholas G Moss, Dorothy A Riguera, Robert M Solinga, Marco M Kessler, Daniel P Zimmer

Hypertension· May 2009

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CD4+ T cells and CXC chemokines modulate the pathogenesis of Staphylococcus aureus wound infections.
Rachel M McLoughlin, Robert M Solinga, Jeremy Rich, Kathleen J Zaleski, Jordan L Cocchiaro

Proc Natl Acad Sci U S A· July 2006

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Immunization with Staphylococcus aureus clumping factor B, a major determinant in nasal carriage, reduces nasal colonization in a murine model.
Adam C Schaffer, Robert M Solinga, Jordan Cocchiaro, Marta Portoles, Kevin B Kiser

Infect Immun· April 2006

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Molecular characterization of the capsule locus from non-typeable Staphylococcus aureus.
Jordan L Cocchiaro, Marisa I Gomez, Allison Risley, Robert Solinga, Daniel O Sordelli

Mol Microbiol· February 2006

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