Publications by authors named "Roberta Bosotti"

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Adducins regulate morphology and fate of neural progenitors during neocortical neurogenesis.
Chiara Ossola, Nikola Cokorac, Emanuele Capra, Stefania Faletti, Ilaria Bertani, Roberta Bosotti

Cell Rep· September 2025

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RNAdetector: a free user-friendly stand-alone and cloud-based system for RNA-Seq data analysis.
Alessandro La Ferlita, Salvatore Alaimo, Sebastiano Di Bella, Emanuele Martorana, Georgios I Laliotis, Roberta Bosotti

BMC Bioinformatics· June 2021

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A benchmarking of pipelines for detecting ncRNAs from RNA-Seq data.
Sebastiano Di Bella, Alessandro La Ferlita, Giovanni Carapezza, Salvatore Alaimo, Antonella Isacchi, Roberta Bosotti

Brief Bioinform· December 2020

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Mining potentially actionable kinase gene fusions in cancer cell lines with the KuNG FU database.
Alessio Somaschini, Sebastiano Di Bella, Carlo Cusi, Laura Raddrizzani, Antonella Leone, Roberta Bosotti

Sci Data· November 2020

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Comprehensive kinome NGS targeted expression profiling by KING-REX.
Giovanni Carapezza, Carlo Cusi, Ettore Rizzo, Laura Raddrizzani, Sebastiano Di Bella, Roberta Bosotti

BMC Genomics· April 2019

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Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and Brachyury.
Paola Magnaghi, Barbara Salom, Liviana Cozzi, Nadia Amboldi, Dario Ballinari, Roberta Bosotti

Mol Cancer Ther· March 2018

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Establishment and genomic characterization of the new chordoma cell line Chor-IN-1.
Roberta Bosotti, Paola Magnaghi, Sebastiano Di Bella, Liviana Cozzi, Carlo Cusi

Sci Rep· August 2017

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Identification and characterization of a novel rearrangement in a colorectal cancer patient.
Massimo Milione, Elena Ardini, Jason Christiansen, Emanuele Valtorta, Silvio Veronese, Roberta Bosotti

Oncotarget· August 2017

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KAOS: a new automated computational method for the identification of overexpressed genes.
Angelo Nuzzo, Giovanni Carapezza, Sebastiano Di Bella, Alfredo Pulvirenti, Antonella Isacchi, Roberta Bosotti

BMC Bioinformatics· November 2016

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Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA-approved compounds.
Diego Carrella, Isabella Manni, Barbara Tumaini, Rosanna Dattilo, Federica Papaccio, Roberta Bosotti

Oncotarget· September 2016

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Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications.
Elena Ardini, Maria Menichincheri, Patrizia Banfi, Roberta Bosotti, Cristina De Ponti

Mol Cancer Ther· April 2016

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Sensitivity to Entrectinib Associated With a Novel LMNA-NTRK1 Gene Fusion in Metastatic Colorectal Cancer.
Andrea Sartore-Bianchi, Elena Ardini, Roberta Bosotti, Alessio Amatu, Emanuele Valtorta

J Natl Cancer Inst· January 2016

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Novel CAD-ALK gene rearrangement is drugable by entrectinib in colorectal cancer.
Alessio Amatu, Alessio Somaschini, Giulio Cerea, Roberta Bosotti, Emanuele Valtorta

Br J Cancer· December 2015

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Preface: BITS2014, the annual meeting of the Italian Society of Bioinformatics.
Angelo Facchiano, Claudia Angelini, Roberta Bosotti, Alessandro Guffanti, Anna Marabotti

BMC Bioinformatics· September 2015

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The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition.
Elena Ardini, Roberta Bosotti, Andrea Lombardi Borgia, Cristina De Ponti, Alessio Somaschini

Mol Oncol· December 2014

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Cell line identity finding by fingerprinting, an optimized resource for short tandem repeat profile authentication.
Alessio Somaschini, Nadia Amboldi, Angelo Nuzzo, Emanuela Scacheri, Giorgio Ukmar, Roberta Bosotti

Genet Test Mol Biomarkers· March 2013

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Transcriptional analysis of the Aurora inhibitor Danusertib leading to biomarker identification in TP53 wild type cells.
Roberta Bosotti, Patrizia Carpinelli, Sandra Healy, Giuseppe Locatelli, Paolo Cappella

Gene· February 2012

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Summarizing probe intensities of affymetrix GeneChip 3' expression arrays taking into account day-to-day variability.
Paolo Magni, Angela Simeone, Sandra Healy, Antonella Isacchi, Roberta Bosotti

IEEE/ACM Trans Comput Biol Bioinform· January 2012

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Identification of candidate substrates for poly(ADP-ribose) polymerase-2 (PARP2) in the absence of DNA damage using high-density protein microarrays.
Sonia Troiani, Rosita Lupi, Rita Perego, Stefania Re Depaolini, Sandrine Thieffine, Roberta Bosotti

FEBS J· October 2011

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Abcg2 overexpression represents a novel mechanism for acquired resistance to the multi-kinase inhibitor Danusertib in BCR-ABL-positive cells in vitro.
Stefan Balabanov, Artur Gontarewicz, Gunhild Keller, Laura Raddrizzani, Melanie Braig, Roberta Bosotti

PLoS One· April 2011

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Discovery of drug mode of action and drug repositioning from transcriptional responses.
Francesco Iorio, Roberta Bosotti, Emanuela Scacheri, Vincenzo Belcastro, Pratibha Mithbaokar

Proc Natl Acad Sci U S A· August 2010

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Transcriptional analysis of an E2F gene signature as a biomarker of activity of the cyclin-dependent kinase inhibitor PHA-793887 in tumor and skin biopsies from a phase I clinical study.
Giuseppe Locatelli, Roberta Bosotti, Marina Ciomei, Maria G Brasca, Raffaele Calogero

Mol Cancer Ther· May 2010

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Cdc7 kinase inhibitors: pyrrolopyridinones as potential antitumor agents. 1. Synthesis and structure-activity relationships.
Ermes Vanotti, Raffaella Amici, Alberto Bargiotti, Jens Berthelsen, Roberta Bosotti

J Med Chem· February 2008

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Cross platform microarray analysis for robust identification of differentially expressed genes.
Roberta Bosotti, Giuseppe Locatelli, Sandra Healy, Emanuela Scacheri, Luca Sartori

BMC Bioinformatics· March 2007

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PoInTree: a polar and interactive phylogenetic tree.
Marco Carreras, Eleonora Gianti, Luca Sartori, Simon Edward Plyte, Antonella Isacchi, Roberta Bosotti

Genomics Proteomics Bioinformatics· February 2005

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