Publications by authors named "Roberta Tesch"

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Development of Selective Pyrido[2,3-]pyrimidin-7(8)-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors.
Marcel Rak, Amelie Menge, Roberta Tesch, Lena M Berger, Dimitrios-Ilias Balourdas

J Med Chem· March 2024

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Shifting the selectivity of pyrido[2,3-d]pyrimidin-7(8H)-one inhibitors towards the salt-inducible kinase (SIK) subfamily.
Marcel Rak, Roberta Tesch, Lena M Berger, Ekaterina Shevchenko, Monika Raab

Eur J Med Chem· June 2023

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Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.
Stanislav Andreev, Tatu Pantsar, Roberta Tesch, Niclas Kahlke, Ahmed El-Gokha

J Med Chem· January 2022

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The Small-Molecule Inhibitor MRIA9 Reveals Novel Insights into the Cell Cycle Roles of SIK2 in Ovarian Cancer Cells.
Monika Raab, Marcel Rak, Roberta Tesch, Khayal Gasimli, Sven Becker

Cancers (Basel)· July 2021

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Structure-Based Design of Selective Salt-Inducible Kinase Inhibitors.
Roberta Tesch, Marcel Rak, Monika Raab, Lena M Berger, Thales Kronenberger

J Med Chem· June 2021

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A Highly Selective Chemical Probe for Activin Receptor-like Kinases ALK4 and ALK5.
Thomas Hanke, Jong Fu Wong, Benedict-Tilman Berger, Ismahan Abdi, Lena Marie Berger, Roberta Tesch

ACS Chem Biol· April 2020

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Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib.
Raquel Carvalho Montenegro, Alison Howarth, Alessandro Ceroni, Vita Fedele, Batoul Farran, Roberta Tesch

Oncotarget· February 2020

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Fast Iterative Synthetic Approach toward Identification of Novel Highly Selective p38 MAP Kinase Inhibitors.
Sandra Röhm, Benedict-Tilman Berger, Martin Schröder, Apirat Chaikuad, Rob Winkel, Roberta Tesch

J Med Chem· December 2019

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Pyridinylimidazoles as dual glycogen synthase kinase 3β/p38α mitogen-activated protein kinase inhibitors.
Fabian Heider, Francesco Ansideri, Roberta Tesch, Tatu Pantsar, Urs Haun

Eur J Med Chem· August 2019

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An Unusual Intramolecular Halogen Bond Guides Conformational Selection.
Roberta Tesch, Christian Becker, Matthias Philipp Müller, Michael Edmund Beck, Lena Quambusch

Angew Chem Int Ed Engl· July 2018

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LASSBio-897 Reduces Lung Injury Induced by Silica Particles in Mice: Potential Interaction with the A Receptor.
Vinicius F Carvalho, Tatiana P T Ferreira, Ana C S de Arantes, François Noël, Roberta Tesch

Front Pharmacol· October 2017

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Identification and further development of potent TBK1 inhibitors.
André Richters, Debjit Basu, Julian Engel, Meryem S Ercanoglu, Hyatt Balke-Want, Roberta Tesch

ACS Chem Biol· January 2015

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Novel potent imidazo[1,2-a]pyridine-N-Glycinyl-hydrazone inhibitors of TNF-α production: in vitro and in vivo studies.
Renata B Lacerda, Natália M Sales, Leandro L da Silva, Roberta Tesch, Ana Luisa P Miranda

PLoS One· December 2014

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Acylhydrazone derivatives: a patent review.
Rodolfo do Couto Maia, Roberta Tesch, Carlos Alberto Manssour Fraga

Expert Opin Ther Pat· November 2014

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N-acylhydrazone derivative ameliorates monocrotaline-induced pulmonary hypertension through the modulation of adenosine AA2R activity.
Allan K N Alencar, Sharlene L Pereira, Flavia E da Silva, Luiza V P Mendes, Valéria do M N Cunha, Roberta Tesch

Int J Cardiol· May 2014

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Novel 2-chloro-4-anilino-quinazoline derivatives as EGFR and VEGFR-2 dual inhibitors.
Maria Letícia de Castro Barbosa, Lídia Moreira Lima, Roberta Tesch, Carlos Mauricio R Sant'Anna, Frank Totzke

Eur J Med Chem· January 2014

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Beneficial effects of a novel agonist of the adenosine A2A receptor on monocrotaline-induced pulmonary hypertension in rats.
Allan K N Alencar, Sharlene L Pereira, Tadeu L Montagnoli, Rodolfo C Maia, Arthur E Kümmerle, Roberta Tesch

Br J Pharmacol· July 2013

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Phenylpiperazine derivatives: a patent review (2006 - present).
Rodolfo do Couto Maia, Roberta Tesch, Carlos Alberto Manssour Fraga

Expert Opin Ther Pat· October 2012

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Antihypertensive profile of 2-thienyl-3,4-methylenedioxybenzoylhydrazone is mediated by activation of the A2A adenosine receptor.
Carla Moreira Leal, Sharlene Lopes Pereira, Arthur Eugen Kümmerle, Daniella Moreira Leal, Roberta Tesch

Eur J Med Chem· September 2012

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