Publications by authors named "Roberto Pacifici"

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Gender-affirming hormone therapy preserves skeletal maturation in young mice via the gut microbiome.
Subhashis Pal, Xochitl Morgan, Hamid Y Dar, Camilo Anthony Gacasan, Sanchiti Patil, Roberto Pacifici

J Clin Invest· March 2024

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Differences in hepatocellular iron metabolism underlie sexual dimorphism in hepatocyte ferroptosis.
Hui Tao, Hamid Y Dar, Cheng Tian, Somesh Banerjee, Evan S Glazer, Roberto Pacifici

Redox Biol· November 2023

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A two-cohort study on the association between the gut microbiota and bone density, microarchitecture, and strength.
Paul C Okoro, Eric S Orwoll, Curtis Huttenhower, Xochitl Morgan, Thomas M Kuntz, Roberto Pacifici

Front Endocrinol (Lausanne)· November 2023

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Inflammation and gut dysbiosis as drivers of CKD-MBD.
Pieter Evenepoel, Peter Stenvinkel, Catherine Shanahan, Roberto Pacifici

Nat Rev Nephrol· October 2023

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Differences in Hepatocellular Iron Metabolism Underlie Sexual Dimorphism in Hepatocyte Ferroptosis.
Hui Tao, Hamid Y Dar, Cheng Tian, Somesh Banerjee, Evan S Glazer, Roberto Pacifici

bioRxiv· June 2023

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Dietary phosphorus consumption alters T cell populations, cytokine production, and bone volume in mice.
Joseph L Roberts, Mingcan Yu, Manjula Viggeswarapu, Jamie L Arnst, Roberto Pacifici

JCI Insight· May 2023

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Callus γδ T cells and microbe-induced intestinal Th17 cells improve fracture healing in mice.
Hamid Y Dar, Daniel S Perrien, Subhashis Pal, Andreea Stoica, Sasidhar Uppuganti, Roberto Pacifici

J Clin Invest· April 2023

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A TrkB agonist prodrug prevents bone loss via inhibiting asparagine endopeptidase and increasing osteoprotegerin.
Jing Xiong, Jianming Liao, Xia Liu, Zhaohui Zhang, Jonathan Adams, Roberto Pacifici

Nat Commun· August 2022

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Cyclic Adenosine Monophosphate (cAMP)-Dependent Phosphodiesterase Inhibition Promotes Bone Anabolism Through CD8 T Cell Wnt-10b Production in Mice.
Susanne Roser-Page, Daiana Weiss, Tatyana Vikulina, Mingcan Yu, Roberto Pacifici

JBMR Plus· July 2022

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The microbiome restrains melanoma bone growth by promoting intestinal NK and Th1 cell homing to bone.
Subhashis Pal, Daniel S Perrien, Tetsuya Yumoto, Roberta Faccio, Andreea Stoica, Roberto Pacifici

J Clin Invest· June 2022

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Role of Gut Microbiota in the Skeletal Response to PTH.
Roberto Pacifici

J Clin Endocrinol Metab· March 2021

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Plasma high-resolution metabolomics identifies linoleic acid and linked metabolic pathways associated with bone mineral density.
Moriah P Bellissimo, Thomas R Ziegler, Dean P Jones, Ken H Liu, Jolyn Fernandes, Roberto Pacifici

Clin Nutr· February 2021

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Ovariectomy induces bone loss via microbial-dependent trafficking of intestinal TNF+ T cells and Th17 cells.
Mingcan Yu, Subhashis Pal, Cameron W Paterson, Jau-Yi Li, Abdul Malik Tyagi, Roberto Pacifici

J Clin Invest· February 2021

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The gut microbiota is a transmissible determinant of skeletal maturation.
Abdul Malik Tyagi, Trevor M Darby, Emory Hsu, Mingcan Yu, Subhashis Pal, Roberto Pacifici

Elife· January 2021

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Metabolomic Associations with Serum Bone Turnover Markers.
Moriah P Bellissimo, Joseph L Roberts, Dean P Jones, Ken H Liu, Kaitlin R Taibl, Roberto Pacifici

Nutrients· October 2020

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Parathyroid hormone-dependent bone formation requires butyrate production by intestinal microbiota.
Jau-Yi Li, Mingcan Yu, Subhashis Pal, Abdul Malik Tyagi, Hamid Dar, Roberto Pacifici

J Clin Invest· April 2020

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Proceedings of the 2018 Santa Fe Bone Symposium: Advances in the Management of Osteoporosis.
E Michael Lewiecki, John P Bilezikian, Lora Giangregorio, Susan L Greenspan, Sundeep Khosla, Roberto Pacifici

J Clin Densitom· March 2020

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PTH induces bone loss via microbial-dependent expansion of intestinal TNF T cells and Th17 cells.
Mingcan Yu, Abdul Malik Tyagi, Jau-Yi Li, Jonathan Adams, Timothy L Denning, Roberto Pacifici

Nat Commun· January 2020

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The gut-bone axis: how bacterial metabolites bridge the distance.
Mario M Zaiss, Rheinallt M Jones, Georg Schett, Roberto Pacifici

J Clin Invest· July 2019

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IL-17 Receptor Signaling in Osteoblasts/Osteocytes Mediates PTH-Induced Bone Loss and Enhances Osteocytic RANKL Production.
Jau-Yi Li, Mingcan Yu, Abdul Malik Tyagi, Chiara Vaccaro, Emory Hsu, Roberto Pacifici

J Bone Miner Res· February 2019

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The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression.
Abdul Malik Tyagi, Mingcan Yu, Trevor M Darby, Chiara Vaccaro, Jau-Yi Li, Roberto Pacifici

Immunity· December 2018

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From Osteoimmunology to Osteomicrobiology: How the Microbiota and the Immune System Regulate Bone.
Emory Hsu, Roberto Pacifici

Calcif Tissue Int· May 2018

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Bone Remodeling and the Microbiome.
Roberto Pacifici

Cold Spring Harb Perspect Med· April 2018

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CTLA-4Ig (abatacept) balances bone anabolic effects of T cells and Wnt-10b with antianabolic effects of osteoblastic sclerostin.
Susanne Roser-Page, Tatyana Vikulina, Daiana Weiss, Mark M Habib, George R Beck, Roberto Pacifici

Ann N Y Acad Sci· March 2018

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Regulatory T cells are expanded by Teriparatide treatment in humans and mediate intermittent PTH-induced bone anabolism in mice.
Mingcan Yu, Patrizia D'Amelio, Abdul Malik Tyagi, Chiara Vaccaro, Jau-Yi Li, Roberto Pacifici

EMBO Rep· January 2018

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