Publications by authors named "Subhashis Pal"

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Discovery of an Orally Active PDE1 Inhibitor for Disease-Modifying Treatment of Postmenopausal Osteoporosis via Dual Anabolic-Antiresorptive Mechanisms.
Farman M Abbasi, Konica Porwal, Subhashis Pal, Shivani Sharma, Sreyanko Sadhukhan

J Med Chem· October 2025

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Anti-Microbial Drug Metronidazole Promotes Fracture Healing: Enhancement in the Bone Regenerative Efficacy of the Drug by a Biodegradable Sustained-Release In Situ Gel Formulation.
Shivali Duggal, Shivani Sharma, Nikhil Rai, Divya Chauhan, Vishal Upadhyay, Subhashis Pal

Biomedicines· July 2024

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The Role of Osteogenic Effect and Vascular Function in Bone Health in Hypertensive Rats: A Study of Anti-hypertensive and Hemorheologic Drugs.
Subhashis Pal, Shivani Sharma, Konica Porwal, Mahesh C Tiwari, Yasir A Khan

Calcif Tissue Int· March 2024

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Gender-affirming hormone therapy preserves skeletal maturation in young mice via the gut microbiome.
Subhashis Pal, Xochitl Morgan, Hamid Y Dar, Camilo Anthony Gacasan, Sanchiti Patil

J Clin Invest· March 2024

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TRPV4 regulates osteoblast differentiation and mitochondrial function that are relevant for channelopathy.
Tusar Kanta Acharya, Subhashis Pal, Arijit Ghosh, Shamit Kumar, Satish Kumar

Front Cell Dev Biol· June 2023

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Callus γδ T cells and microbe-induced intestinal Th17 cells improve fracture healing in mice.
Hamid Y Dar, Daniel S Perrien, Subhashis Pal, Andreea Stoica, Sasidhar Uppuganti

J Clin Invest· April 2023

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Editorial: Expert opinion in bone research: 2021.
Subhashis Pal

Front Endocrinol (Lausanne)· December 2022

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Oral Administration of Isovitexin, a Naturally Occurring Apigenin Derivative Showed Osteoanabolic Effect in Ovariectomized Mice: A Comparative Study with Teriparatide.
Subhashis Pal, Shivani Sharma, Konica Porwal, Mohammed Riyazuddin, Chirag Kulkarni

Calcif Tissue Int· August 2022

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Sirt3 ameliorates mitochondrial dysfunction and oxidative stress through regulating mitochondrial biogenesis and dynamics in cardiomyoblast.
Paramesha Bugga, Md Jahangir Alam, Roshan Kumar, Subhashis Pal, Naibedya Chattopadyay

Cell Signal· June 2022

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The microbiome restrains melanoma bone growth by promoting intestinal NK and Th1 cell homing to bone.
Subhashis Pal, Daniel S Perrien, Tetsuya Yumoto, Roberta Faccio, Andreea Stoica

J Clin Invest· June 2022

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Diosmin, a citrus fruit-derived phlebotonic bioflavonoid protects rats from chronic kidney disease-induced loss of bone mass and strength without deteriorating the renal function.
Shivani Sharma, Konica Porwal, Chirag Kulkarni, Subhashis Pal, Praveer Sihota

Food Funct· February 2022

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Estradiol overcomes adiponectin-resistance in diabetic mice by regulating skeletal muscle adiponectin receptor 1 expression.
Sourav Chattopadhyay, Amit Joharapurkar, Nabanita Das, Shamima Khatoon, Sapana Kushwaha, Shyamsundar Pal China, Subhashis Pal

Mol Cell Endocrinol· January 2022

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Adiponectin receptors by increasing mitochondrial biogenesis and respiration promote osteoblast differentiation: Discovery of isovitexin as a new class of small molecule adiponectin receptor modulator with potential osteoanabolic function.
Subhashis Pal, Maninder Singh, Konica Porwal, Sangam Rajak, Nabanita Das

Eur J Pharmacol· December 2021

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Therapeutic potential of phosphodiesterase inhibitors in the treatment of osteoporosis: Scopes for therapeutic repurposing and discovery of new oral osteoanabolic drugs.
Konica Porwal, Subhashis Pal, Sudha Bhagwati, Mohd Imran Siddiqi, Naibedya Chattopadhyay

Eur J Pharmacol· May 2021

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Self-Assembling Nano-Globular Peptide from Human Lactoferrin Acts as a Systemic Enhancer of Bone Regeneration: A Novel Peptide for Orthopedic Application.
Subhashis Pal, Mohd Sayeed, Amit Kumar, Devesh P Verma, Munesh K Harioudh

ACS Appl Mater Interfaces· April 2021

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TRPM8 channel inhibitor-encapsulated hydrogel as a tunable surface for bone tissue engineering.
Tusar Kanta Acharya, Satish Kumar, Nikhil Tiwari, Arijit Ghosh, Ankit Tiwari, Subhashis Pal

Sci Rep· February 2021

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Ovariectomy induces bone loss via microbial-dependent trafficking of intestinal TNF+ T cells and Th17 cells.
Mingcan Yu, Subhashis Pal, Cameron W Paterson, Jau-Yi Li, Abdul Malik Tyagi

J Clin Invest· February 2021

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The gut microbiota is a transmissible determinant of skeletal maturation.
Abdul Malik Tyagi, Trevor M Darby, Emory Hsu, Mingcan Yu, Subhashis Pal

Elife· January 2021

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Calcium repletion to rats with calcipenic rickets fails to recover bone quality: A calcipenic "memory".
Shivmurat Yadav, Subhashis Pal, Priya Singh, Konica Porwal, Rohit Anthony Sinha

Bone· December 2020

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A prebiotic, short-chain fructo-oligosaccharides promotes peak bone mass and maintains bone mass in ovariectomized rats by an osteogenic mechanism.
Konica Porwal, Subhashis Pal, Chirag Kulkarni, Priya Singh, Shivani Sharma

Biomed Pharmacother· September 2020

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Selective dietary polyphenols induce differentiation of human osteoblasts by adiponectin receptor 1-mediated reprogramming of mitochondrial energy metabolism.
Subhashis Pal, Konica Porwal, Sangam Rajak, Rohit A Sinha, Naibedya Chattopadhyay

Biomed Pharmacother· July 2020

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Skeletal restoration by phosphodiesterase 5 inhibitors in osteopenic mice: Evidence of osteoanabolic and osteoangiogenic effects of the drugs.
Subhashis Pal, Mamunur Rashid, Sandeep Kumar Singh, Konica Porwal, Priya Singh

Bone· June 2020

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Parathyroid hormone-dependent bone formation requires butyrate production by intestinal microbiota.
Jau-Yi Li, Mingcan Yu, Subhashis Pal, Abdul Malik Tyagi, Hamid Dar

J Clin Invest· April 2020

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Standardized Xylocarpus moluccensis fruit fraction mitigates collagen-induced arthritis in mice by regulating immune response.
Priya Gupta, Amit Kumar, Subhashis Pal, Sachin Kumar, Amit Lahiri

J Pharm Pharmacol· April 2020

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A butanolic fraction from the standardized stem extract of Cassia occidentalis L delivered by a self-emulsifying drug delivery system protects rats from glucocorticoid-induced osteopenia and muscle atrophy.
Subhashis Pal, Naresh Mittapelly, Athar Husain, Sapana Kushwaha, Sourav Chattopadhyay, Eppalapally Ramakrishna

Sci Rep· January 2020

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