Publications by authors named "Robin F Irvine"

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Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.
Ismael Al-Ramahi, Sai Srinivas Panapakkam Giridharan, Yu-Chi Chen, Samarjit Patnaik, Nathaniel Safren, Robin F Irvine

Elife· December 2017

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A short history of inositol lipids.
Robin F Irvine

J Lipid Res· November 2016

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In B cells, phosphatidylinositol 5-phosphate 4-kinase-α synthesizes PI(4,5)P2 to impact mTORC2 and Akt signaling.
Simon J Bulley, Alaa Droubi, Jonathan H Clarke, Karen E Anderson, Len R Stephens, Robin F Irvine

Proc Natl Acad Sci U S A· September 2016

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Nuclear localizations of phosphatidylinositol 5-phosphate 4-kinases α and β are dynamic and independently regulated during starvation-induced stress.
Alaa Droubi, Simon J Bulley, Jonathan H Clarke, Robin F Irvine

Biochem J· July 2016

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Phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ), a lipid signalling enigma.
Maria-Luisa Giudici, Jonathan H Clarke, Robin F Irvine

Adv Biol Regul· May 2016

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There is no 'Conundrum' of InsP6.
Robin F Irvine, Simon J Bulley, Miranda S Wilson, Adolfo Saiardi

Open Biol· November 2015

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The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site.
Jonathan H Clarke, Maria-Luisa Giudici, John E Burke, Roger L Williams, David J Maloney, Robin F Irvine

Biochem J· March 2015

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A novel method for the purification of inositol phosphates from biological samples reveals that no phytate is present in human plasma or urine.
Miranda S C Wilson, Simon J Bulley, Francesca Pisani, Robin F Irvine, Adolfo Saiardi

Open Biol· March 2015

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Exploring phosphatidylinositol 5-phosphate 4-kinase function.
Simon J Bulley, Jonathan H Clarke, Alaa Droubi, Maria-Luisa Giudici, Robin F Irvine

Adv Biol Regul· January 2015

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Absence of detectable inositol hexakisphosphate (phytate) in plasma.
Robin F Irvine

J Chromatogr B Analyt Technol Biomed Life Sci· June 2014

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Enzyme activity of the PIP4K2A gene product polymorphism that is implicated in schizophrenia.
Jonathan H Clarke, Robin F Irvine

Psychopharmacology (Berl)· November 2013

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Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization.
Jonathan H Clarke, Robin F Irvine

Biochem J· August 2013

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PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity.
Gerald R V Hammond, Michael J Fischer, Karen E Anderson, Jon Holdich, Ardita Koteci, Robin F Irvine

Science· August 2012

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The activity, evolution and association of phosphatidylinositol 5-phosphate 4-kinases.
Jonathan H Clarke, Robin F Irvine

Adv Biol Regul· January 2012

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Cell biology. Pyro-technic control of metabolism.
Robin F Irvine, Richard M Denton

Science· November 2011

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Phosphatidylinositol 4-phosphate 5-kinase Iγ_v6, a new splice variant found in rodents and humans.
Yang Xia, Robin F Irvine, Maria-Luisa Giudici

Biochem Biophys Res Commun· July 2011

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A femtomole-sensitivity mass assay for inositol hexakisphosphate.
Andrew J Letcher, Michael J Schell, Robin F Irvine

Methods Mol Biol· October 2010

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Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases IIalpha and IIbeta and a partial nuclear localization of the IIalpha isoform.
Minchuan Wang, Nicholas J Bond, Andrew J Letcher, Jonathan P Richardson, Kathryn S Lilley, Robin F Irvine

Biochem J· September 2010

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Localization, regulation and function of type II phosphatidylinositol 5-phosphate 4-kinases.
Jonathan H Clarke, Michael Wang, Robin F Irvine

Adv Enzyme Regul· August 2010

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Distribution and neuronal expression of phosphatidylinositol phosphate kinase IIgamma in the mouse brain.
Jonathan H Clarke, Piers C Emson, Robin F Irvine

J Comp Neurol· November 2009

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Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2).
Gerald R V Hammond, Giampietro Schiavo, Robin F Irvine

Biochem J· July 2009

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Reversible binding and rapid diffusion of proteins in complex with inositol lipids serves to coordinate free movement with spatial information.
Gerald R V Hammond, Yirong Sim, Leon Lagnado, Robin F Irvine

J Cell Biol· January 2009

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Do mammals make all their own inositol hexakisphosphate?
Andrew J Letcher, Michael J Schell, Robin F Irvine

Biochem J· December 2008

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Localization of phosphatidylinositol phosphate kinase IIgamma in kidney to a membrane trafficking compartment within specialized cells of the nephron.
Jonathan H Clarke, Piers C Emson, Robin F Irvine

Am J Physiol Renal Physiol· November 2008

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Regulation of inositol 1,4,5-trisphosphate 3-kinases by calcium and localization in cells.
Samantha M Lloyd-Burton, Jowie C H Yu, Robin F Irvine, Michael J Schell

J Biol Chem· March 2007

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