Publications by authors named "Robin Graf"

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Gene-editing in patient and humanized-mice primary muscle stem cells rescues dysferlin expression in dysferlin-deficient muscular dystrophy.
Helena Escobar, Silvia Di Francescantonio, Julia Smirnova, Robin Graf, Stefanie Müthel

Nat Commun· January 2025

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In vivo CRISPR/Cas9-mediated screen reveals a critical function of TFDP1 and E2F4 transcription factors in hematopoiesis.
Ngoc Tung Tran, Robin Graf, Ernesto Acevedo-Ochoa, Janine Trombke, Timm Weber

Leukemia· September 2024

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Precise CRISPR-Cas-mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells.
Ngoc Tung Tran, Eric Danner, Xun Li, Robin Graf, Mikhail Lebedin

Sci Adv· June 2022

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B-Cell-Specific Myd88 L252P Expression Causes a Premalignant Gammopathy Resembling IgM MGUS.
Kristin Schmidt, Ulrike Sack, Robin Graf, Wiebke Winkler, Oliver Popp

Front Immunol· June 2021

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CRISPR-Cas9-Mediated ELANE Mutation Correction in Hematopoietic Stem and Progenitor Cells to Treat Severe Congenital Neutropenia.
Ngoc Tung Tran, Robin Graf, Annika Wulf-Goldenberg, Maria Stecklum, Gabriele Strauß

Mol Ther· December 2020

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PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
Verónica Delgado-Benito, Maria Berruezo-Llacuna, Robert Altwasser, Wiebke Winkler, Devakumar Sundaravinayagam, Robin Graf

J Exp Med· October 2020

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Efficient CRISPR/Cas9-Mediated Gene Knockin in Mouse Hematopoietic Stem and Progenitor Cells.
Ngoc Tung Tran, Thomas Sommermann, Robin Graf, Janine Trombke, Jenniffer Pempe

Cell Rep· September 2019

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BCR-dependent lineage plasticity in mature B cells.
Robin Graf, Jane Seagal, Kevin L Otipoby, Kong-Peng Lam, Salah Ayoub

Science· February 2019

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sgRNA Sequence Motifs Blocking Efficient CRISPR/Cas9-Mediated Gene Editing.
Robin Graf, Xun Li, Van Trung Chu, Klaus Rajewsky

Cell Rep· January 2019

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CRISPR/Cas9-Mediated In Vitro Mutagenesis in GC-Like B Cells.
Van Trung Chu, Robin Graf, Klaus Rajewsky

Methods Mol Biol· March 2018

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Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line.
Van Trung Chu, Robin Graf, Tristan Wirtz, Timm Weber, Jeremy Favret

Proc Natl Acad Sci U S A· November 2016

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Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes.
Van Trung Chu, Timm Weber, Robin Graf, Thomas Sommermann, Kerstin Petsch

BMC Biotechnol· January 2016

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PI3 Kinase and FOXO1 Transcription Factor Activity Differentially Control B Cells in the Germinal Center Light and Dark Zones.
Sandrine Sander, Van Trung Chu, Tomoharu Yasuda, Andrew Franklin, Robin Graf

Immunity· December 2015

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Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation.
Robin Graf, Mathias Munschauer, Guido Mastrobuoni, Florian Mayr, Udo Heinemann

RNA Biol· July 2013

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