Publications by authors named "Roger Gunn"

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Connecting the dots: approaching a standardized nomenclature for molecular connectivity in positron emission tomography.
Murray B Reed, Luca Cocchi, Christin Y Sander, Jingyuan Chen, Granville J Matheson, Roger N Gunn

Eur J Nucl Med Mol Imaging· December 2025

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Role of Serotonin in the Neurobiology of Schizophrenia and Association With Negative Symptoms.
Martin Osugo, Thomas Whitehurst, David Erritzoe, Richard Carr, Abhishekh H Ashok, Roger N Gunn

JAMA Psychiatry· December 2025

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Alzheimer's Imaging Consortium.
Alexis Moscoso, Antoine Leuzy, Lars Lau Raket, Victor L Villemagne, Gregory Klein, Roger N Gunn

Alzheimers Dement· December 2025

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EC images reveal reproducible spatial variation in drug affinity across single- and repeat-dose occupancy studies.
Alaaddin Ibrahimy, Su Jin Kim, Mark E Schmidt, Mark Slifstein, Erik Mannaert, Roger N Gunn

J Cereb Blood Flow Metab· November 2025

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An in vivo PET/CT investigation of mitochondrial complex 1, sigma 1, and synaptic vesicle 2 A in patients with amyotrophic lateral sclerosis.
Edoardo R de Natale, Joji P Verghese, Alana Terry, Heather Wilson, Pegah Khosropanah, Roger Gunn

Neurobiol Dis· November 2025

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Interplay between astrocyte reactivity and APOE ε4 status is associated with accelerated pTau-related tau pathology in Alzheimer's disease.
Xiaoxie Mao, Yan Wang, Ying Luan, Ying Wang, Jie Wang, Roger N Gunn

Mol Neurodegener· October 2025

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Evaluation of Mitochondrial Complex 1 Density with [F]BCPP-EF in a Murine Model and Individuals with Friedreich Ataxia.
Laigao Chen, Gaia Rizzo, Christine Bulawa, Koene R A Van Dijk, Erica C Henning, Roger N Gunn

J Nucl Med· September 2025

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Mitochondria and Cognition: An [F]BCPP-EF Positron Emission Tomography Study of Mitochondrial Complex I Levels and Brain Activation During Task Switching.
Ekaterina Shatalina, Thomas Whitehurst, Ellis Chika Onwordi, Alexander Whittington, Ayla Mansur, Roger N Gunn

Biol Psychiatry Cogn Neurosci Neuroimaging· August 2025

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Quantifying VMAT2 target occupancy at effective valbenazine doses and comparing to a novel VMAT2 inhibitor: a translational PET study.
Ryan Terry-Lorenzo, Daniel Albrecht, Sabrinia Crouch, Richard Wong, Gordon Loewen, Roger N Gunn

Neuropsychopharmacology· June 2025

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Correction: Quantifying VMAT2 target occupancy at effective valbenazine doses and comparing to a novel VMAT2 inhibitor: a translational PET study.
Ryan Terry-Lorenzo, Daniel Albrecht, Sabrinia Crouch, Richard Wong, Gordon Loewen, Roger N Gunn

Neuropsychopharmacology· March 2025

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The relationship between cortical synaptic terminal density marker SV2A and glutamate early in the course of schizophrenia: a multimodal PET and MRS imaging study.
Ellis Chika Onwordi, Thomas Whitehurst, Ekaterina Shatalina, Richard Carr, Ayla Mansur, Roger N Gunn

Transl Psychiatry· March 2025

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Discovery and clinical translation of ceperognastat, an O-GlcNAcase (OGA) inhibitor, for the treatment of Alzheimer's disease.
William Kielbasa, Paul Goldsmith, Kevin B Donnelly, Hugh N Nuthall, Sergey Shcherbinin, Roger N Gunn

Alzheimers Dement (N Y)· December 2024

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Study protocol for the iMarkHD study in individuals with Huntington's disease.
Daniel J van Wamelen, Naomi H Martin, Orsolya Makos, James Badenoch, Jose Manuel Valera-Bermejo, Roger Gunn

J Huntingtons Dis· November 2024

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Harmonizing tau positron emission tomography in Alzheimer's disease: The CenTauR scale and the joint propagation model.
Antoine Leuzy, Lars Lau Raket, Victor L Villemagne, Gregory Klein, Matteo Tonietto, Roger N Gunn

Alzheimers Dement· September 2024

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The relationship between SV2A levels, neural activity, and cognitive function in healthy humans: A [11C]UCB-J PET and fMRI study.
Ekaterina Shatalina, Ellis Chika Onwordi, Thomas Whitehurst, Alexander Whittington, Ayla Mansur, Roger N Gunn

Imaging Neurosci (Camb)· June 2024

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Synaptic Terminal Density Early in the Course of Schizophrenia: An In Vivo UCB-J Positron Emission Tomographic Imaging Study of SV2A.
Ellis Chika Onwordi, Thomas Whitehurst, Ekaterina Shatalina, Ayla Mansur, Atheeshaan Arumuham, Roger N Gunn

Biol Psychiatry· April 2024

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Estimation of target occupancy in repeated dosing design studies using positron emission tomography: Biases due to target upregulation.
Eugenii A Rabiner, Roger N Gunn

J Cereb Blood Flow Metab· April 2024

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Validation of quantitative assessment of florbetaben PET scans as an adjunct to the visual assessment across 15 software methods.
Aleksandar Jovalekic, Núria Roé-Vellvé, Norman Koglin, Mariana Lagos Quintana, Aaron Nelson, Roger Gunn

Eur J Nucl Med Mol Imaging· September 2023

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Brain Serotonin Release Is Reduced in Patients With Depression: A [C]Cimbi-36 Positron Emission Tomography Study With a d-Amphetamine Challenge.
David Erritzoe, Beata R Godlewska, Gaia Rizzo, Graham E Searle, Claudio Agnorelli, Roger N Gunn

Biol Psychiatry· June 2023

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Application of Aligned-UMAP to longitudinal biomedical studies.
Anant Dadu, Vipul K Satone, Rachneet Kaur, Mathew J Koretsky, Hirotaka Iwaki, Roger Gunn

Patterns (N Y)· June 2023

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A PET-CT study on neuroinflammation in Huntington's disease patients participating in a randomized trial with laquinimod.
Andreas-Antonios Roussakis, Marta Gennaro, Mark Forrest Gordon, Ralf Reilmann, Beth Borowsky, Roger N Gunn

Brain Commun· April 2023

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A Visual Interpretation Algorithm for Assessing Brain Tauopathy with F-MK-6240 PET.
John P Seibyl, Jonathan M DuBois, Annie Racine, Jessica Collins, Qi Guo, Roger N Gunn

J Nucl Med· March 2023

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Evaluation of Intraperitoneal [F]-FDOPA Administration for Micro-PET Imaging in Mice and Assessment of the Effect of Subchronic Ketamine Dosing on Dopamine Synthesis Capacity.
Els F Halff, Sridhar Natesan, David R Bonsall, Mattia Veronese, Anna Garcia-Hidalgo, Roger N Gunn

Mol Imaging· February 2023

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Neurons derived from individual early Alzheimer's disease patients reflect their clinical vulnerability.
Bryan Ng, Helen A Rowland, Tina Wei, Kanisa Arunasalam, Emma Mee Hayes, Roger N Gunn

Brain Commun· October 2022

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Astrogliosis in aging and Parkinson's disease dementia: a new clinical study with C-BU99008 PET.
Mohamed A Mohamed, Zhou Zeng, Marta Gennaro, Nicholas P Lao-Kaim, Jim F M Myers, Roger N Gunn

Brain Commun· August 2022

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