Publications by authors named "Roger Habets"

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The anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition.
Judith Hounjet, Roger Habets, Marco B Schaaf, Tessa C Hendrickx, Lydie M O Barbeau

Oncogene· July 2019

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Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition.
Roger A Habets, Charles E de Bock, Lutgarde Serneels, Inge Lodewijckx, Delphine Verbeke

Sci Transl Med· May 2019

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NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma.
Sanaz Yahyanejad, Henry King, Venus Sosa Iglesias, Patrick V Granton, Lydie M O Barbeau, Roger Habets

Oncotarget· July 2016

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Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool.
Ragna Sannerud, Cary Esselens, Paulina Ejsmont, Rafael Mattera, Leila Rochin, Roger Habets

Cell· June 2016

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Insights into Autoregulation of Notch3 from Structural and Functional Studies of Its Negative Regulatory Region.
Xiang Xu, Sung Hee Choi, Tiancen Hu, Kittichoat Tiyanont, Roger Habets

Structure· July 2015

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Human NOTCH2 Is Resistant to Ligand-independent Activation by Metalloprotease Adam17.
Roger A J Habets, Arjan J Groot, Sanaz Yahyanejad, Kittichoat Tiyanont, Stephen C Blacklow

J Biol Chem· June 2015

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Regulated proteolysis of NOTCH2 and NOTCH3 receptors by ADAM10 and presenilins.
Arjan J Groot, Roger Habets, Sanaz Yahyanejad, Caroline M Hodin, Karina Reiss

Mol Cell Biol· August 2014

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High NOTCH activity induces radiation resistance in non small cell lung cancer.
Jan Theys, Sanaz Yahyanejad, Roger Habets, Paul Span, Ludwig Dubois

Radiother Oncol· September 2013

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E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells.
Jan Theys, Barry Jutten, Roger Habets, Kim Paesmans, Arjan J Groot

Radiother Oncol· June 2011

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