Publications by authors named "Roger Sandhoff"

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Predicting GD2 expression across cancer types by the integration of pathway topology and transcriptome data.
Arsenij Ustjanzew, Federico Marini, Saskia Wagner, Arthur Wingerter, Roger Sandhoff

Front Bioinform· December 2025

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The SGLT2 Inhibitor Dapagliflozin Disrupts the Cell Cycle at High Concentrations Without Altering Glycosphingolipid (De Novo)Biosynthesis.
Richard Jennemann, Roger Sandhoff

Int J Mol Sci· October 2025

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Ganglioside Profiling Uncovers Distinct Patterns in High-Risk Neuroblastoma.
Claudia Paret, Arthur Wingerter, Larissa Seidmann, Arsenij Ustjanzew, Shobha Sathyamurthy, Roger Sandhoff

Int J Mol Sci· August 2025

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Autosomal Dominant Lamellar Ichthyosis Due to a Missense Variant in the Gene NKPD1.
Katalin Komlosi, Cristina Glocker, Hao-Hsiang Hsu-Rehder, Svenja Alter, Julia Kopp, Roger Sandhoff

J Invest Dermatol· December 2024

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Glucosylceramide Synthase Inhibition in Combination with Aripiprazole Sensitizes Hepatocellular Cancer Cells to Sorafenib and Doxorubicin.
Richard Jennemann, Martina Volz, Roberto Carlos Frias-Soler, Almut Schulze, Karsten Richter, Roger Sandhoff

Int J Mol Sci· December 2024

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Unraveling the glycosphingolipid metabolism by leveraging transcriptome-weighted network analysis on neuroblastic tumors.
Arsenij Ustjanzew, Annekathrin Silvia Nedwed, Roger Sandhoff, Jörg Faber, Federico Marini

Cancer Metab· October 2024

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Sphinganine recruits TLR4 adaptors in macrophages and promotes inflammation in murine models of sepsis and melanoma.
Marvin Hering, Alaa Madi, Roger Sandhoff, Sicong Ma, Jingxia Wu

Nat Commun· July 2024

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Serine enrichment in tumors promotes regulatory T cell accumulation through sphinganine-mediated regulation of c-Fos.
Sicong Ma, Roger Sandhoff, Xiu Luo, Fuwei Shang, Qiaozhen Shi

Sci Immunol· April 2024

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Lipid Structure Matters in Lysosomal Storage Disease.
Roger Sandhoff

J Lipid Res· December 2023

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DKK3 Promotes Oxidative Stress‒Induced Fibroblast Activity.
Sabrina Muecklich, Khuram Shehzad, Jessica Tiemann, Li Li, Sonja Leson, Roger Sandhoff

J Invest Dermatol· June 2023

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Glucosylceramide Synthase Inhibitors Induce Ceramide Accumulation and Sensitize H3K27 Mutant Diffuse Midline Glioma to Irradiation.
Khalifa El Malki, Pia Wehling, Francesca Alt, Roger Sandhoff, Sebastian Zahnreich

Int J Mol Sci· June 2023

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Sphingosine-1-Phosphate Recruits Macrophages and Microglia and Induces a Pro-Tumorigenic Phenotype That Favors Glioma Progression.
Lavinia Arseni, Rakesh Sharma, Norman Mack, Deepthi Nagalla, Sibylle Ohl, Roger Sandhoff

Cancers (Basel)· January 2023

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GD2 Expression in Medulloblastoma and Neuroblastoma for Personalized Immunotherapy: A Matter of Subtype.
Claudia Paret, Arsenij Ustjanzew, Sara Ersali, Larissa Seidmann, Richard Jennemann, Roger Sandhoff

Cancers (Basel)· December 2022

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Neuronal Ganglioside and Glycosphingolipid (GSL) Metabolism and Disease : Cascades of Secondary Metabolic Errors Can Generate Complex Pathologies (in LSDs).
Roger Sandhoff, Konrad Sandhoff

Adv Neurobiol· October 2022

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A Clathrin light chain A reporter mouse for in vivo imaging of endocytosis.
Elisabeth Grimm, Franciscus van der Hoeven, Donato Sardella, Katrin I Willig, Ulrike Engel, Roger Sandhoff

PLoS One· September 2022

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Epidermal 1-O-acylceramides appear with the establishment of the water permeability barrier in mice and are produced by maturating keratinocytes.
Mariona Rabionet, Pauline Bernard, Melanie Pichery, Christian Marsching, Aline Bayerle, Roger Sandhoff

Lipids· May 2022

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Interaction between Bacteria and the Immune System for Cancer Immunotherapy: The α-GalCer Alliance.
Arsenij Ustjanzew, Valentin Sencio, François Trottein, Jörg Faber, Roger Sandhoff

Int J Mol Sci· May 2022

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Formation of keto-type ceramides in palmoplantar keratoderma based on biallelic KDSR mutations in patients.
Robert Pilz, Lukáš Opálka, Adam Majcher, Elisabeth Grimm, Lionel Van Maldergem, Roger Sandhoff

Hum Mol Genet· March 2022

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Blockade of Glycosphingolipid Synthesis Inhibits Cell Cycle and Spheroid Growth of Colon Cancer Cells In Vitro and Experimental Colon Cancer Incidence In Vivo.
Richard Jennemann, Martina Volz, Felix Bestvater, Claudia Schmidt, Karsten Richter, Roger Sandhoff

Int J Mol Sci· September 2021

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The prognostic value of galactosylceramide-sulfotransferase (Gal3ST1) in human renal cell carcinoma.
Stefan Porubsky, Malin Nientiedt, Maximilian C Kriegmair, Jörn-Helge Heinrich Siemoneit, Roger Sandhoff

Sci Rep· May 2021

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Tumor Lipids of Pediatric Papillary Renal Cell Carcinoma Stimulate Unconventional T Cells.
Nadine Lehmann, Claudia Paret, Khalifa El Malki, Alexandra Russo, Marie Astrid Neu, Roger Sandhoff

Front Immunol· April 2021

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Glycolipid-dependent and lectin-driven transcytosis in mouse enterocytes.
Alena Ivashenka, Christian Wunder, Valerie Chambon, Roger Sandhoff, Richard Jennemann

Commun Biol· February 2021

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Exploiting Gangliosides for the Therapy of Ewing's Sarcoma and H3K27M-Mutant Diffuse Midline Glioma.
Arthur Wingerter, Khalifa El Malki, Roger Sandhoff, Larissa Seidmann, Daniel-Christoph Wagner

Cancers (Basel)· January 2021

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Effect of Increased Lactate Dehydrogenase A Activity and Aerobic Glycolysis on the Proinflammatory Profile of Autoimmune CD8+ T Cells in Rheumatoid Arthritis.
M Margarida Souto-Carneiro, Karel D Klika, Mónica T Abreu, André P Meyer, Rainer Saffrich, Roger Sandhoff

Arthritis Rheumatol· December 2020

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