Publications by authors named "Konrad Sandhoff"

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From amaurotic idiocy to biochemically defined lipid storage diseases: the first identification of GM1-Gangliosidosis.
Burkhard S Kasper, Christian Thomas, Anne Albers, Ekkehard M Kasper, Konrad Sandhoff

Free Neuropathol· January 2023

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Neuronal Ganglioside and Glycosphingolipid (GSL) Metabolism and Disease : Cascades of Secondary Metabolic Errors Can Generate Complex Pathologies (in LSDs).
Roger Sandhoff, Konrad Sandhoff

Adv Neurobiol· October 2022

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A case of spastic paraplegia type 11 mimicking a GM2-gangliosidosis.
Diego Lopergolo, Gianna Berti, Francesca Mari, Enrico Bertini, Alessandra Rufa, Konrad Sandhoff

Neurol Sci· April 2022

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Corrigendum to: Emerging mechanisms of drug-induced phospholipidosis.
Bernadette Breiden, Konrad Sandhoff

Biol Chem· October 2021

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Secondary ganglioside GM2 accumulation in mucopolysaccharidoses.
Konrad Sandhoff

Mol Genet Metab Rep· September 2021

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Acid Sphingomyelinase, a Lysosomal and Secretory Phospholipase C, Is Key for Cellular Phospholipid Catabolism.
Bernadette Breiden, Konrad Sandhoff

Int J Mol Sci· August 2021

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Ganglioside GM2 catabolism is inhibited by storage compounds of mucopolysaccharidoses and by cationic amphiphilic drugs.
Susi Anheuser, Bernadette Breiden, Konrad Sandhoff

Mol Genet Metab· April 2020

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Mechanism of Secondary Ganglioside and Lipid Accumulation in Lysosomal Disease.
Bernadette Breiden, Konrad Sandhoff

Int J Mol Sci· April 2020

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Emerging mechanisms of drug-induced phospholipidosis.
Bernadette Breiden, Konrad Sandhoff

Biol Chem· December 2019

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In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism.
Nesli-Ece Sen, Aleksandar Arsovic, David Meierhofer, Susanne Brodesser, Carola Oberschmidt, Konrad Sandhoff

Int J Mol Sci· November 2019

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Membrane lipids and their degradation compounds control GM2 catabolism at intralysosomal luminal vesicles.
Susi Anheuser, Bernadette Breiden, Konrad Sandhoff

J Lipid Res· June 2019

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Lysosomal Glycosphingolipid Storage Diseases.
Bernadette Breiden, Konrad Sandhoff

Annu Rev Biochem· June 2019

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Ganglioside Metabolism and Its Inherited Diseases.
Bernadette Breiden, Konrad Sandhoff

Methods Mol Biol· March 2019

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Ganglioside Metabolism in Health and Disease.
Roger Sandhoff, Heike Schulze, Konrad Sandhoff

Prog Mol Biol Transl Sci· February 2019

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Emerging concepts of ganglioside metabolism.
Roger Sandhoff, Konrad Sandhoff

FEBS Lett· December 2018

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Inactivation of ceramide synthase 2 catalytic activity in mice affects transcription of genes involved in lipid metabolism and cell division.
Andreas Bickert, Paul Kern, Martina van Uelft, Stefanie Herresthal, Thomas Ulas, Konrad Sandhoff

Biochim Biophys Acta Mol Cell Biol Lipids· July 2018

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Unbalanced lipolysis results in lipotoxicity and mitochondrial damage in peroxisome-deficient mutants.
Margret H Bülow, Christian Wingen, Deniz Senyilmaz, Dominic Gosejacob, Mariangela Sociale, Konrad Sandhoff

Mol Biol Cell· February 2018

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Ceramide Synthase Schlank Is a Transcriptional Regulator Adapting Gene Expression to Energy Requirements.
Mariangela Sociale, Anna-Lena Wulf, Bernadette Breiden, Kathrin Klee, Melanie Thielisch, Konrad Sandhoff

Cell Rep· January 2018

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Characterization of mutants as a model for lysosomal sphingolipid storage diseases.
Julia Sellin, Heike Schulze, Marie Paradis, Dominic Gosejacob, Cyrus Papan, Konrad Sandhoff

Dis Model Mech· June 2017

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Synthetic Glycoforms Reveal Carbohydrate-Dependent Bioactivity of Human Saposin D.
Christopher G F Graf, Christian Schulz, Marina Schmälzlein, Christian Heinlein, Manuel Mönnich, Konrad Sandhoff

Angew Chem Int Ed Engl· May 2017

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Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.
Sophie Schonauer, Heinz G Körschen, Anke Penno, Andreas Rennhack, Bernadette Breiden, Konrad Sandhoff

J Biol Chem· April 2017

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Lipids regulate the hydrolysis of membrane bound glucosylceramide by lysosomal β-glucocerebrosidase.
Misbaudeen Abdul-Hammed, Bernadette Breiden, Günter Schwarzmann, Konrad Sandhoff

J Lipid Res· March 2017

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Neuronal sphingolipidoses: Membrane lipids and sphingolipid activator proteins regulate lysosomal sphingolipid catabolism.
Konrad Sandhoff

Biochimie· November 2016

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Membrane-spanning lipids for an uncompromised monitoring of membrane fusion and intermembrane lipid transfer.
Günter Schwarzmann, Bernadette Breiden, Konrad Sandhoff

J Lipid Res· October 2015

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Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity.
Susi Anheuser, Bernadette Breiden, Günter Schwarzmann, Konrad Sandhoff

J Lipid Res· September 2015

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