Publications by authors named "Rohan Mendonca"

Claim this Profile
D
Discovery of GNE-6893, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of HPK1.
John C Tellis, BinQing Wei, Michael Siu, Le An, Grace Kayan Chan, Rohan Mendonca

ACS Med Chem Lett· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Implementation of the CYP Index for the Design of Selective Tryptophan-2,3-dioxygenase Inhibitors.
Brendan T Parr, Richard Pastor, Benjamin D Sellers, Zhonghua Pei, Firoz A Jaipuri, Rohan Mendonca

ACS Med Chem Lett· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling.
Mark Zak, Emily J Hanan, Patrick Lupardus, David G Brown, Colin Robinson, Rohan Mendonca

Bioorg Med Chem Lett· June 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Aminoisoxazoles as Potent Inhibitors of Tryptophan 2,3-Dioxygenase 2 (TDO2).
Zhonghua Pei, Rohan Mendonca, Lewis Gazzard, Richard Pastor, Leanne Goon

ACS Med Chem Lett· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel triazolo-pyrrolopyridines as inhibitors of Janus kinase 1.
Christopher A Hurley, Wade S Blair, Richard J Bull, Christine Chang, Peter H Crackett, Rohan Mendonca

Bioorg Med Chem Lett· June 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of C-2 hydroxyethyl imidazopyrrolopyridines as potent JAK1 inhibitors with favorable physicochemical properties and high selectivity over JAK2.
Mark Zak, Christopher A Hurley, Stuart I Ward, Philippe Bergeron, Kathy Barrett, Rohan Mendonca

J Med Chem· June 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2.
Sharada Labadie, Peter S Dragovich, Kathy Barrett, Wade S Blair, Philippe Bergeron, Rohan Mendonca

Bioorg Med Chem Lett· December 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2.
Mark Zak, Rohan Mendonca, Mercedesz Balazs, Kathy Barrett, Philippe Bergeron

J Med Chem· July 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of imidazo-pyrrolopyridines as novel and potent JAK1 inhibitors.
Janusz J Kulagowski, Wade Blair, Richard J Bull, Christine Chang, Gauri Deshmukh, Rohan Mendonca

J Med Chem· June 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase.
Zhengying Pan, Heleen Scheerens, Shyr-Jiann Li, Brian E Schultz, Paul A Sprengeler, Rohan V Mendonca

ChemMedChem· January 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel, potent, selective, and orally bioavailable human betaII-tryptase inhibitors.
David Sperandio, Vincent W-F Tai, Julia Lohman, Bernie Hirschbein, Rohan Mendonca

Bioorg Med Chem Lett· August 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design and synthesis of selective keto-1,2,4-oxadiazole-based tryptase inhibitors.
James T Palmer, Robert M Rydzewski, Rohan V Mendonca, David Sperandio, Jeffrey R Spencer

Bioorg Med Chem Lett· July 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Optimization of subsite binding to the beta5 subunit of the human 20S proteasome using vinyl sulfones and 2-keto-1,3,4-oxadiazoles: syntheses and cellular properties of potent, selective proteasome inhibitors.
Robert M Rydzewski, Leland Burrill, Rohan Mendonca, James T Palmer, Mark Rice

J Med Chem· May 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K.
James T Palmer, Clifford Bryant, Dan-Xiong Wang, Dana E Davis, Eduardo L Setti, Rohan V Mendonca

J Med Chem· December 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Adenosine kinase inhibitors. 5. Synthesis, enzyme inhibition, and analgesic activity of diaryl-erythro-furanosyltubercidin analogues.
Serge H Boyer, Bheemarao G Ugarkar, Joel Solbach, Joseph Kopcho, Michael C Matelich, Rohan Mendonca

J Med Chem· October 2005

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel class of nonpeptidic biaryl inhibitors of human cathepsin K.
Joël Robichaud, Renata Oballa, Peppi Prasit, Jean-Pierre Falgueyret, M David Percival, Rohan Mendonca

J Med Chem· August 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel route to the synthesis of peptides containing 2-amino-1'-hydroxymethyl ketones and their application as cathepsin K inhibitors.
Rohan V Mendonca, Shankar Venkatraman, James T Palmer

Bioorg Med Chem Lett· October 2002

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis