Publications by authors named "Stuart I Ward"

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Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy.
Jack A Terrett, Huifen Chen, Daniel G Shore, Elisia Villemure, Robin Larouche-Gauthier, Stuart I Ward

J Med Chem· April 2021

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TRPA1 modulation by piperidine carboxamides suggests an evolutionarily conserved binding site and gating mechanism.
Tania Chernov-Rogan, Eleonora Gianti, Chang Liu, Elisia Villemure, Andrew P Cridland, Stuart I Ward

Proc Natl Acad Sci U S A· December 2019

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A reversed sulfonamide series of selective RORc inverse agonists.
Monique B van Niel, Benjamin P Fauber, Matthew Cartwright, Simon Gaines, Jonathan C Killen, Stuart I Ward

Bioorg Med Chem Lett· December 2014

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Novel triazolo-pyrrolopyridines as inhibitors of Janus kinase 1.
Christopher A Hurley, Wade S Blair, Richard J Bull, Christine Chang, Peter H Crackett, Stuart I Ward

Bioorg Med Chem Lett· June 2013

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Identification of C-2 hydroxyethyl imidazopyrrolopyridines as potent JAK1 inhibitors with favorable physicochemical properties and high selectivity over JAK2.
Mark Zak, Christopher A Hurley, Stuart I Ward, Philippe Bergeron, Kathy Barrett

J Med Chem· June 2013

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Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2.
Mark Zak, Rohan Mendonca, Mercedesz Balazs, Kathy Barrett, Philippe Bergeron, Stuart I Ward

J Med Chem· July 2012

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Identification of imidazo-pyrrolopyridines as novel and potent JAK1 inhibitors.
Janusz J Kulagowski, Wade Blair, Richard J Bull, Christine Chang, Gauri Deshmukh, Stuart I Ward

J Med Chem· June 2012

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