Publications by authors named "Roland Staal"

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Inhibition of P2X7 receptors by Lu AF27139 diminishes colonic hypersensitivity and CNS prostanoid levels in a rat model of visceral pain.
Roland G W Staal, Adarsh Gandhi, Hua Zhou, Manuel Cajina, Anne-Marie Jacobsen

Purinergic Signal· December 2022

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P2X7 receptor-mediated release of microglial prostanoids and miRNAs correlates with reversal of neuropathic hypersensitivity in rats.
Roland Staal, Tanzilya Khayrullina, Rie Christensen, Sara Hestehave, Hua Zhou

Eur J Pain· July 2022

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Synthesis and Characterization of the Novel Rodent-Active and CNS-Penetrant P2X7 Receptor Antagonist Lu AF27139.
Allen T Hopper, Martin Juhl, Jorrit Hornberg, Lassina Badolo, John Paul Kilburn, Roland Staal

J Med Chem· April 2021

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Microglial Drug Targets in AD: Opportunities and Challenges in Drug Discovery and Development.
Knut Biber, Anindya Bhattacharya, Brian M Campbell, Justin R Piro, Michael Rohe, Roland G W Staal

Front Pharmacol· August 2019

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Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State.
Martin Kurnik, Cagla Sahin, Camilla Bertel Andersen, Nikolai Lorenzen, Lise Giehm, Roland Staal

Cell Chem Biol· November 2018

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Senicapoc: Repurposing a Drug to Target Microglia K3.1 in Stroke.
Roland G W Staal, Jonathan R Weinstein, Megan Nattini, Manuel Cajina, Gamini Chandresana

Neurochem Res· September 2017

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Quantitative analysis of lipids: a higher-throughput LC-MS/MS-based method and its comparison to ELISA.
Adarsh S Gandhi, David Budac, Tanzilya Khayrullina, Roland Staal, Gamini Chandrasena

Future Sci OA· March 2017

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Inhibition of the potassium channel K3.1 by senicapoc reverses tactile allodynia in rats with peripheral nerve injury.
Roland G W Staal, Tanzilya Khayrullina, Hong Zhang, Scott Davis, Shaun M Fallon

Eur J Pharmacol· January 2017

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KCa 3.1-a microglial target ready for drug repurposing?
Elena Dale, Roland G W Staal, Claudia Eder, Thomas Möller

Glia· October 2016

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Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor.
Thomas Möller, Frédérique Bard, Anindya Bhattacharya, Knut Biber, Brian Campbell, Roland G W Staal

Glia· October 2016

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Dopamine release at individual presynaptic terminals visualized with FFNs.
Hui Zhang, Niko G Gubernator, Minerva Yue, Roland G W Staal, Eugene V Mosharov

J Vis Exp· August 2009

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Fluorescent false neurotransmitters visualize dopamine release from individual presynaptic terminals.
Niko G Gubernator, Hui Zhang, Roland G W Staal, Eugene V Mosharov, Daniela B Pereira

Science· June 2009

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PKC theta activity maintains normal quantal size in chromaffin cells.
Roland G W Staal, Anthonia Hananiya, David Sulzer

J Neurochem· June 2008

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Alpha-synuclein overexpression increases cytosolic catecholamine concentration.
Eugene V Mosharov, Roland G W Staal, Jordi Bové, Delphine Prou, Anthonia Hananiya

J Neurosci· September 2006

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Sorting of vesicular monoamine transporter 2 to the regulated secretory pathway confers the somatodendritic exocytosis of monoamines.
Haiyan Li, Clarissa L Waites, Roland G Staal, Yuriy Dobryy, Jeanna Park

Neuron· November 2005

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Dopamine neurons release transmitter via a flickering fusion pore.
Roland G W Staal, Eugene V Mosharov, David Sulzer

Nat Neurosci· April 2004

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Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.
William Dauer, Nikolai Kholodilov, Miquel Vila, Anne-Cecile Trillat, Rose Goodchild, Roland Staal

Proc Natl Acad Sci U S A· October 2002

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8-(3-Chlorostyryl)caffeine may attenuate MPTP neurotoxicity through dual actions of monoamine oxidase inhibition and A2A receptor antagonism.
Jiang-Fan Chen, Salome Steyn, Roland Staal, Jacobus P Petzer, Kui Xu

J Biol Chem· September 2002

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