Publications by authors named "Roman Fleck"

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Dual STAT3/STAT5 inhibition as a novel treatment strategy in T-prolymphocytic leukemia.
Annika Dechow, Sanna Timonen, Aleksandr Ianevski, Qu Jiang, Linus Wahnschaffe, Roman Fleck

Leukemia· June 2025

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Dual specific STAT3/5 degraders effectively block acute myeloid leukemia and natural killer/T cell lymphoma.
Daniel Pölöske, Helena Sorger, Anna Schönbichler, Elvin D de Araujo, Heidi A Neubauer, Roman Fleck

Hemasphere· December 2024

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Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.
Tobias Suske, Helena Sorger, Gabriele Manhart, Frank Ruge, Nicole Prutsch, Roman Fleck

J Clin Invest· April 2024

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Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T-cell lymphoma.
Helena Sorger, Saptaswa Dey, Pablo Augusto Vieyra-Garcia, Daniel Pölöske, Andrea R Teufelberger, Roman Fleck

EMBO Mol Med· December 2022

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Trends in Personalized Therapies in Oncology: The (Venture) Capitalist's Perspective.
Roman Fleck, Daniel Bach

J Pers Med· March 2012

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Substituted pyrazoles as novel sEH antagonist: investigation of key binding interactions within the catalytic domain.
Ho Yin Lo, Chuk C Man, Roman W Fleck, Neil A Farrow, Richard H Ingraham

Bioorg Med Chem Lett· November 2010

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The discovery of thienopyridine analogues as potent IkappaB kinase beta inhibitors. Part II.
Jiang-Ping Wu, Roman Fleck, Janice Brickwood, Alison Capolino, Katrina Catron

Bioorg Med Chem Lett· October 2009

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2-Aminobenzimidazoles as potent ITK antagonists: trans-stilbene-like moieties targeting the kinase specificity pocket.
Ho Yin Lo, Jörg Bentzien, Roman W Fleck, Steven S Pullen, Hnin Hnin Khine

Bioorg Med Chem Lett· December 2008

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