Publications by authors named "Roman Laskowski"

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In silico prediction of heme binding in proteins.
Noa A Marson, Andrea E Gallio, Suman K Mandal, Roman A Laskowski, Emma L Raven

J Biol Chem· May 2024

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The effects of pathogenic and likely pathogenic variants for inherited hemostasis disorders in 140 214 UK Biobank participants.
Luca Stefanucci, Janine Collins, Matthew C Sims, Inigo Barrio-Hernandez, Luanluan Sun, Roman A Laskowski

Blood· December 2023

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Mapping the Constrained Coding Regions in the Human Genome to Their Corresponding Proteins.
Marcia A Hasenahuer, Alba Sanchis-Juan, Roman A Laskowski, James A Baker, James D Stephenson

J Mol Biol· January 2023

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PDBsum1: A standalone program for generating PDBsum analyses.
Roman A Laskowski

Protein Sci· December 2022

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A structural biology community assessment of AlphaFold2 applications.
Mehmet Akdel, Douglas E V Pires, Eduard Porta Pardo, Jürgen Jänes, Arthur O Zalevsky, Roman A Laskowski

Nat Struct Mol Biol· November 2022

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PDBsum extras: SARS-CoV-2 and AlphaFold models.
Roman A Laskowski, Janet M Thornton

Protein Sci· January 2022

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AlphaFold heralds a data-driven revolution in biology and medicine.
Janet M Thornton, Roman A Laskowski, Neera Borkakoti

Nat Med· October 2021

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A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.
Lorena Magraner-Pardo, Roman A Laskowski, Tirso Pons, Janet M Thornton

Sci Rep· July 2021

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Impact of Structural Observables From Simulations to Predict the Effect of Single-Point Mutations in MHC Class II Peptide Binders.
Rodrigo Ochoa, Roman A Laskowski, Janet M Thornton, Pilar Cossio

Front Mol Biosci· March 2021

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An automated protocol for modelling peptide substrates to proteases.
Rodrigo Ochoa, Mikhail Magnitov, Roman A Laskowski, Pilar Cossio, Janet M Thornton

BMC Bioinformatics· December 2020

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VarSite: Disease variants and protein structure.
Roman A Laskowski, James D Stephenson, Ian Sillitoe, Christine A Orengo, Janet M Thornton

Protein Sci· January 2020

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VarMap: a web tool for mapping genomic coordinates to protein sequence and structure and retrieving protein structural annotations.
James D Stephenson, Roman A Laskowski, Andrew Nightingale, Matthew E Hurles, Janet M Thornton

Bioinformatics· November 2019

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The ProFunc Function Prediction Server.
Roman A Laskowski

Methods Mol Biol· February 2018

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PDBsum: Structural summaries of PDB entries.
Roman A Laskowski, Jagoda Jabłońska, Lukáš Pravda, Radka Svobodová Vařeková, Janet M Thornton

Protein Sci· January 2018

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Protein Structure Databases.
Roman A Laskowski

Methods Mol Biol· December 2017

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Protein structure and phenotypic analysis of pathogenic and population missense variants in .
Mohnish Suri, Jochem M G Evers, Roman A Laskowski, Sinead O'Brien, Kate Baker

Mol Genet Genomic Med· September 2017

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Sequence-Specific Recognition of DNA by Proteins: Binding Motifs Discovered Using a Novel Statistical/Computational Analysis.
David Jakubec, Roman A Laskowski, Jiri Vondrasek

PLoS One· July 2017

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Structural analysis of pathogenic mutations in the DYRK1A gene in patients with developmental disorders.
Jochem M G Evers, Roman A Laskowski, Marta Bertolli, Jill Clayton-Smith, Charu Deshpande

Hum Mol Genet· February 2017

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BetaSCPWeb: side-chain prediction for protein structures using Voronoi diagrams and geometry prioritization.
Joonghyun Ryu, Mokwon Lee, Jehyun Cha, Roman A Laskowski, Seong Eon Ryu

Nucleic Acids Res· July 2016

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Chopping and Changing: the Evolution of the Flavin-dependent Monooxygenases.
Maria Laura Mascotti, Maximiliano Juri Ayub, Nicholas Furnham, Janet M Thornton, Roman A Laskowski

J Mol Biol· July 2016

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Rising levels of atmospheric oxygen and evolution of Nrf2.
Ranko Gacesa, Walter C Dunlap, David J Barlow, Roman A Laskowski, Paul F Long

Sci Rep· June 2016

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Integrating population variation and protein structural analysis to improve clinical interpretation of missense variation: application to the WD40 domain.
Roman A Laskowski, Nidhi Tyagi, Diana Johnson, Shelagh Joss, Esther Kinning

Hum Mol Genet· March 2016

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Proteins: interaction at a distance.
Roman A Laskowski, Janet M Thornton

IUCrJ· November 2015

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Representative Amino Acid Side-Chain Interactions in Protein-DNA Complexes: A Comparison of Highly Accurate Correlated Ab Initio Quantum Mechanical Calculations and Efficient Approaches for Applications to Large Systems.
Jiří Hostaš, Dávid Jakubec, Roman A Laskowski, Ramachandran Gnanasekaran, Jan Řezáč

J Chem Theory Comput· September 2015

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Large-Scale Quantitative Assessment of Binding Preferences in Protein-Nucleic Acid Complexes.
Dávid Jakubec, Jirí Hostas, Roman A Laskowski, Pavel Hobza, Jirí Vondrásek

J Chem Theory Comput· April 2015

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