Publications by authors named "Ronald Realubit"

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Systematic elucidation and pharmacologic targeting on non-oncogene dependencies in imatinib-resistant gastrointestinal stromal tumor.
Prabhjot S Mundi, Adina Grunn, Arsenije Kojadinovic, Charles Karan, Ronald Realubit

bioRxiv· October 2025

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Correction: Inhibition of NF-κB-Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma.
Grazia Ambrosini, Catherine Do, Benjamin Tycko, Ronald B Realubit, Charles Karan

Cancer Res· August 2025

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Discovering Venom-Derived Drug Candidates Using Differential Gene Expression.
Joseph D Romano, Hai Li, Tanya Napolitano, Ronald Realubit, Charles Karan

Toxins (Basel)· July 2023

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A Transcriptome-Based Precision Oncology Platform for Patient-Therapy Alignment in a Diverse Set of Treatment-Resistant Malignancies.
Prabhjot S Mundi, Filemon S Dela Cruz, Adina Grunn, Daniel Diolaiti, Audrey Mauguen, Ronald Realubit

Cancer Discov· June 2023

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Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators.
Aleksandar Obradovic, Casey Ager, Mikko Turunen, Thomas Nirschl, Mohsen Khosravi-Maharlooei, Ronald Realubit

Cancer Cell· May 2023

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OncoLoop: A Network-Based Precision Cancer Medicine Framework.
Alessandro Vasciaveo, Juan Martín Arriaga, Francisca Nunes de Almeida, Min Zou, Eugene F Douglass, Ronald Realubit

Cancer Discov· February 2023

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A model for network-based identification and pharmacological targeting of aberrant, replication-permissive transcriptional programs induced by viral infection.
Pasquale Laise, Megan L Stanifer, Gideon Bosker, Xiaoyun Sun, Sergio Triana, Ronald B Realubit

Commun Biol· July 2022

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A Model for Network-Based Identification and Pharmacological Targeting of Aberrant, Replication-Permissive Transcriptional Programs Induced by Viral Infection.
Pasquale Laise, Megan L Stanifer, Gideon Bosker, Xiaoyun Sun, Sergio Triana, Ronald B Realubit

Res Sq· February 2022

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TOP2B Enzymatic Activity on Promoters and Introns Modulates Multiple Oncogenes in Human Gliomas.
Edgar Gonzalez-Buendia, Junfei Zhao, Lu Wang, Subhas Mukherjee, Daniel Zhang, Ronald Realubit

Clin Cancer Res· October 2021

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The transcriptomic response of cells to a drug combination is more than the sum of the responses to the monotherapies.
Jennifer El Diaz, Mehmet Eren Ahsen, Thomas Schaffter, Xintong Chen, Ronald B Realubit

Elife· September 2020

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The Host Cell ViroCheckpoint: Identification and Pharmacologic Targeting of Novel Mechanistic Determinants of Coronavirus-Mediated Hijacked Cell States.
Pasquale Laise, Gideon Bosker, Xiaoyun Sun, Yao Shen, Eugene F Douglass, Ronald B Realubit

bioRxiv· May 2020

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Reply to 'H-STS, L-STS and KRJ-I are not authentic GEPNET cell lines'.
Mariano J Alvarez, Pengrong Yan, Mary L Alpaugh, Michaela Bowden, Ewa Sicinska, Ronald B Realubit

Nat Genet· October 2019

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Inhibition of NF-κB-Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma.
Grazia Ambrosini, Catherine Do, Benjamin Tycko, Ronald B Realubit, Charles Karan

Cancer Res· May 2019

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A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors.
Mariano J Alvarez, Prem S Subramaniam, Laura H Tang, Adina Grunn, Mahalaxmi Aburi, Ronald B Realubit

Nat Genet· July 2018

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Tissue-Specific Analysis of Pharmacological Pathways.
Yun Hao, Kayla Quinnies, Ronald Realubit, Charles Karan, Nicholas P Tatonetti

CPT Pharmacometrics Syst Pharmacol· July 2018

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Identification of Fluorescent Small Molecule Compounds for Synaptic Labeling by Image-Based, High-Content Screening.
Matthew Dunn, Umed Boltaev, Anne Beskow, Sergey Pampou, Ronald Realubit

ACS Chem Neurosci· April 2018

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PI3Kγ/δ and NOTCH1 Cross-Regulate Pathways That Define the T-cell Acute Lymphoblastic Leukemia Disease Signature.
Evgeni Efimenko, Utpal P Davé, Irina V Lebedeva, Yao Shen, Maria J Sanchez-Quintero, Ronald Realubit

Mol Cancer Ther· October 2017

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Systematic, network-based characterization of therapeutic target inhibitors.
Yao Shen, Mariano J Alvarez, Brygida Bisikirska, Alexander Lachmann, Ronald Realubit

PLoS Comput Biol· October 2017

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PLATE-Seq for genome-wide regulatory network analysis of high-throughput screens.
Erin C Bush, Forest Ray, Mariano J Alvarez, Ronald Realubit, Hai Li

Nat Commun· July 2017

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Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies.
Changchun Deng, Mark R Lipstein, Luigi Scotto, Xavier O Jirau Serrano, Michael A Mangone, Ronald B Realubit

Blood· January 2017

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Bioactive Compound Screen for Pharmacological Enhancers of Apolipoprotein E in Primary Human Astrocytes.
Gina M Finan, Ronald Realubit, Sungkwon Chung, Dieter Lütjohann, Nan Wang

Cell Chem Biol· December 2016

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TSH Receptor Signaling Abrogation by a Novel Small Molecule.
Rauf Latif, Ronald B Realubit, Charles Karan, Mihaly Mezei, Terry F Davies

Front Endocrinol (Lausanne)· September 2016

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A novel, rapid method to compare the therapeutic windows of oral anticoagulants using the Hill coefficient.
Jeremy B Chang, Kayla M Quinnies, Ronald Realubit, Charles Karan, Jacob H Rand

Sci Rep· July 2016

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Elucidating Compound Mechanism of Action by Network Perturbation Analysis.
Jung Hoon Woo, Yishai Shimoni, Wan Seok Yang, Prem Subramaniam, Archana Iyer, Ronald Realubit

Cell· July 2015

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Preclinical pharmacologic evaluation of pralatrexate and romidepsin confirms potent synergy of the combination in a murine model of human T-cell lymphoma.
Salvia Jain, Xavier Jirau-Serrano, Kelly M Zullo, Luigi Scotto, Carmine F Palermo, Ronald Realubit

Clin Cancer Res· May 2015

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