Publications by authors named "Rose Willett"

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Mediation analysis of the molecular phenotypes in a severe MASH-like liver injury mouse model.
Zhuolin Song, Volodymyr P Tryndyak, Rose A Willett, Igor P Pogribny, Ivan Rusyn

Toxicol Sci· November 2025

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Signature gene expression model for quantitative evaluation of MASH-like liver injury in mice.
Volodymyr P Tryndyak, Rose A Willett, Zhuolin Song, Kostiantyn Dreval, Jennifer M Hughes Hanks

Toxicol Appl Pharmacol· September 2025

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A preclinical model of severe NASH-like liver injury by chronic administration of a high-fat and high-sucrose diet in mice.
Rose A Willett, Volodymyr P Tryndyak, Jennifer M Hughes Hanks, Lana Elkins, Suresh K Nagumalli

Toxicol Appl Pharmacol· October 2024

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Cellular and molecular alterations in a human hepatocellular in vitro model of nonalcoholic fatty liver disease development and stratification.
Rose A Willett, Volodymyr P Tryndyak, Frederick A Beland, Igor P Pogribny

J Environ Sci Health C Toxicol Carcinog· January 2024

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TMEM55B links autophagy flux, lysosomal repair, and TFE3 activation in response to oxidative stress.
Eutteum Jeong, Rose Willett, Alberto Rissone, Martina La Spina, Rosa Puertollano

Nat Commun· January 2024

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Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice.
Volodymyr P Tryndyak, Rose A Willett, Suresh K Nagumalli, Dan Li, Mark I Avigan

Am J Physiol Gastrointest Liver Physiol· March 2023

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Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet.
Volodymyr P Tryndyak, Rose A Willett, Mark I Avigan, Arun J Sanyal, Frederick A Beland

Epigenetics· November 2022

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Lipidomic profiling of the hepatic esterified fatty acid composition in diet-induced nonalcoholic fatty liver disease in genetically diverse Collaborative Cross mice.
Suresh K Nagumalli, Rose A Willett, Aline de Conti, Volodymyr P Tryndyak, Mark I Avigan

J Nutr Biochem· November 2022

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Characterization of the variability in the extent of nonalcoholic fatty liver induced by a high-fat diet in the genetically diverse Collaborative Cross mouse model.
Aline de Conti, Volodymyr Tryndyak, Rose A Willett, Barbara Borowa-Mazgaj, Anna Watson

FASEB J· June 2020

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TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes.
Rose Willett, José A Martina, James P Zewe, Rachel Wills, Gerald R V Hammond

Nat Commun· November 2017

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-(1-Benzyl-3,5-dimethyl-1-pyrazol-4-yl)benzamides: Antiproliferative Activity and Effects on mTORC1 and Autophagy.
Teng Ai, Rose Willett, Jessica Williams, Rui Ding, Daniel J Wilson

ACS Med Chem Lett· January 2017

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COG lobe B sub-complex engages v-SNARE GS15 and functions via regulated interaction with lobe A sub-complex.
Rose Willett, Jessica Bailey Blackburn, Leslie Climer, Irina Pokrovskaya, Tetyana Kudlyk

Sci Rep· July 2016

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Expression of functional Myc-tagged conserved oligomeric Golgi (COG) subcomplexes in mammalian cells.
Rose A Willett, Tetyana A Kudlyk, Vladimir V Lupashin

Methods Mol Biol· November 2015

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Fluorescent microscopy as a tool to elucidate dysfunction and mislocalization of Golgi glycosyltransferases in COG complex depleted mammalian cells.
Rose A Willett, Irina D Pokrovskaya, Vladimir V Lupashin

Methods Mol Biol· January 2014

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Multipronged interaction of the COG complex with intracellular membranes.
Rose Willett, Irina Pokrovskaya, Tetyana Kudlyk, Vladimir Lupashin

Cell Logist· January 2014

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The Golgi puppet master: COG complex at center stage of membrane trafficking interactions.
Rose Willett, Daniel Ungar, Vladimir Lupashin

Histochem Cell Biol· September 2013

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COG complexes form spatial landmarks for distinct SNARE complexes.
Rose Willett, Tetyana Kudlyk, Irina Pokrovskaya, Robert Schönherr, Daniel Ungar

Nat Commun· June 2013

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COG6 interacts with a subset of the Golgi SNAREs and is important for the Golgi complex integrity.
Tetyana Kudlyk, Rose Willett, Irina D Pokrovskaya, Vladimir Lupashin

Traffic· February 2013

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Conserved oligomeric Golgi complex specifically regulates the maintenance of Golgi glycosylation machinery.
Irina D Pokrovskaya, Rose Willett, Richard D Smith, Willy Morelle, Tetyana Kudlyk

Glycobiology· December 2011

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The COG complex, Rab6 and COPI define a novel Golgi retrograde trafficking pathway that is exploited by SubAB toxin.
Richard D Smith, Rose Willett, Tetyana Kudlyk, Irina Pokrovskaya, Adrienne W Paton

Traffic· October 2009

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