Publications by authors named "Ross C Gruber"

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BTK regulates microglial function and neuroinflammation in human stem cell models and mouse models of multiple sclerosis.
Ross C Gruber, Gregory S Wirak, Anna S Blazier, Lan Lee, Michael R Dufault

Nat Commun· November 2024

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Comparative CNS Pharmacology of the Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib Versus Other BTK Inhibitor Candidates for Treating Multiple Sclerosis.
Timothy J Turner, Pricilla Brun, Ross C Gruber, Dimitry Ofengeim

Drugs R D· June 2024

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Akt3-Mediated Protection Against Inflammatory Demyelinating Disease.
Juwen C DuBois, Alex K Ray, Ross C Gruber, Yongwei Zhang, Ranee Aflakpui

Front Immunol· October 2020

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The role of TAM family receptors and ligands in the nervous system: From development to pathobiology.
Bridget Shafit-Zagardo, Ross C Gruber, Juwen C DuBois

Pharmacol Ther· August 2018

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Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy.
Enric Mocholi, Samuel D Dowling, Yair Botbol, Ross C Gruber, Alex K Ray

Cell Rep· July 2018

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Loss of Gas6 and Axl signaling results in extensive axonal damage, motor deficits, prolonged neuroinflammation, and less remyelination following cuprizone exposure.
Alex K Ray, Juwen C DuBois, Ross C Gruber, Hillary M Guzik, Maria E Gulinello

Glia· December 2017

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The control of reactive oxygen species production by SHP-1 in oligodendrocytes.
Ross C Gruber, Daria LaRocca, Scott B Minchenberg, George P Christophi, Chad A Hudson

Glia· October 2015

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Targeted GAS6 delivery to the CNS protects axons from damage during experimental autoimmune encephalomyelitis.
Ross C Gruber, Alex K Ray, Christopher T Johndrow, Hillary Guzik, Dominika Burek

J Neurosci· December 2014

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Gas6 enhances axonal ensheathment by MBP+ membranous processes in human DRG/OL promyelinating co-cultures.
Kathleen N O'Guin, Ross C Gruber, Cedric S Raine, Hillary M Guzik, Bradford K Poulos

ASN Neuro· January 2014

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Suppression of inflammatory responses during myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis is regulated by AKT3 signaling.
Vladislav Tsiperson, Ross C Gruber, Michael F Goldberg, Ayana Jordan, Jason G Weinger

J Immunol· February 2013

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Interleukin-33 upregulation in peripheral leukocytes and CNS of multiple sclerosis patients.
George P Christophi, Ross C Gruber, Michael Panos, Rebecca L Christophi, Burk Jubelt

Clin Immunol· March 2012

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Quantitative differences in the immunomodulatory effects of Rebif and Avonex in IFN-β 1a treated multiple sclerosis patients.
George P Christophi, Jennifer A Christophi, Ross C Gruber, Cornelia Mihai, Luis J Mejico

J Neurol Sci· August 2011

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Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype.
George P Christophi, Michael Panos, Chad A Hudson, Rebecca L Christophi, Ross C Gruber

Lab Invest· July 2009

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Modulation of macrophage infiltration and inflammatory activity by the phosphatase SHP-1 in virus-induced demyelinating disease.
George P Christophi, Chad A Hudson, Michael Panos, Ross C Gruber, Paul T Massa

J Virol· January 2009

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Induction of IL-33 expression and activity in central nervous system glia.
Chad A Hudson, George P Christophi, Ross C Gruber, Joel R Wilmore, David A Lawrence

J Leukoc Biol· September 2008

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SHP-1 deficiency and increased inflammatory gene expression in PBMCs of multiple sclerosis patients.
George P Christophi, Chad A Hudson, Ross C Gruber, Christoforos P Christophi, Cornelia Mihai

Lab Invest· March 2008

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Regulation of avoidant behaviors and pain by the anti-inflammatory tyrosine phosphatase SHP-1.
Chad A Hudson, George P Christophi, Ling Cao, Ross C Gruber, Paul T Massa

Neuron Glia Biol· November 2006

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