Publications by authors named "Ross Cagan"

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WNT signalling promotes NF-κB activation and drug resistance in KRAS-mutant colorectal cancer.
Bojie Cong, Evangelia Stamou, Kathryn Pennel, Teena Thakur, Molly Mckenzie, Ross Cagan

EMBO Rep· December 2025

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Colon cancer cells evade drug action by enhancing drug metabolism.
Bojie Cong, Teena Thakur, Alejandro Huerta Uribe, Evangelia Stamou, Sindhura Gopinath, Ross Cagan

Oncogene· September 2025

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Modelling Cancer in Drosophila: Exploration to Personalised Medicine.
Hammed Badmos, Ross Cagan

Adv Exp Med Biol· July 2025

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Functional exploration of copy number alterations in a Drosophila model of triple-negative breast cancer.
Jennifer E L Diaz, Vanessa Barcessat, Christian Bahamon, Chana Hecht, Tirtha K Das, Ross L Cagan

Dis Model Mech· July 2024

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Cell competition and cancer from Drosophila to mammals.
Bojie Cong, Ross L Cagan

Oncogenesis· January 2024

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Colon Cancer Cells Evade Drug Action by Enhancing Drug Metabolism.
Bojie Cong, Teena Thakur, Alejandro Huerta Uribe, Evangelia Stamou, Sindhura Gopinath, Ross Cagan

bioRxiv· December 2023

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WNT Signalling Promotes NF-κB Activation and Drug Resistance in KRAS-Mutant Colorectal Cancer.
Bojie Cong, Evangelia Stamou, Kathryn Pennel, Molly Mckenzie, Amna Matly, Ross Cagan

bioRxiv· December 2023

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RAS Signaling Gone Awry in the Skin: The Complex Role of RAS in Cutaneous Neurofibroma Pathogenesis, Emerging Biological Insights.
Steven D Rhodes, Frank McCormick, Ross L Cagan, Annette Bakker, Verena Staedtke

J Invest Dermatol· August 2023

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Existing and Developing Preclinical Models for Neurofibromatosis Type 1-Related Cutaneous Neurofibromas.
Verena Staedtke, Piotr Topilko, Lu Q Le, Kevin Grimes, David A Largaespada, Ross L Cagan

J Invest Dermatol· August 2023

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A polycistronic transgene design for combinatorial genetic perturbations from a single transcript in Drosophila.
Alexander G Teague, Maria Quintero, Fateme Karimi Dermani, Ross L Cagan, Erdem Bangi

PLoS Genet· June 2023

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Drugging the undruggable: Ross Cagan interviews Kevan Shokat.
Ross Cagan, Kevan Shokat

Dis Model Mech· February 2022

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Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge.
Zhaoping Xiong, Minji Jeon, Robert J Allaway, Jaewoo Kang, Donghyeon Park, Ross Cagan

PLoS Comput Biol· September 2021

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Interdisciplinary case study: from fly-to-bedside, translating basic research to the clinic.
Marshall Posner, Ross Cagan

iScience· April 2021

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Drosophila RASopathy models identify disease subtype differences and biomarkers of drug efficacy.
Tirtha K Das, Jared Gatto, Rupa Mirmira, Ethan Hourizadeh, Dalia Kaufman, Ross Cagan

iScience· April 2021

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A Drosophila platform identifies a novel, personalized therapy for a patient with adenoid cystic carcinoma.
Erdem Bangi, Peter Smibert, Andrew V Uzilov, Alexander G Teague, Sindhura Gopinath, Ross L Cagan

iScience· March 2021

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Inhibition of kinase IKKβ suppresses cellular abnormalities induced by the human papillomavirus oncoprotein HPV 18E6.
Mojgan Padash Barmchi, Miranda Thomas, Jayashree V Thatte, Arushi Vats, Bing Zhang, Ross L Cagan

Sci Rep· January 2021

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Systemic Regulation of Local Cell Competition.
Susumu Hirabayashi, Ross Cagan

Dev Cell· May 2020

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modEnrichr: a suite of gene set enrichment analysis tools for model organisms.
Maxim V Kuleshov, Jennifer E L Diaz, Zachary N Flamholz, Alexandra B Keenan, Alexander Lachmann, Ross L Cagan

Nucleic Acids Res· July 2019

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Modeling Cancer with Flies and Fish.
Ross L Cagan, Leonard I Zon, Richard M White

Dev Cell· May 2019

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A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer.
Erdem Bangi, Celina Ang, Peter Smibert, Andrew V Uzilov, Alexander G Teague, Ross L Cagan

Sci Adv· May 2019

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Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network.
Peter M U Ung, Masahiro Sonoshita, Alex P Scopton, Arvin C Dar, Ross L Cagan

PLoS Comput Biol· April 2019

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Restraining Network Response to Targeted Cancer Therapies Improves Efficacy and Reduces Cellular Resistance.
Tirtha K Das, Jessica Esernio, Ross L Cagan

Cancer Res· August 2018

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A whole-animal platform to advance a clinical kinase inhibitor into new disease space.
Masahiro Sonoshita, Alex P Scopton, Peter M U Ung, Matthew A Murray, Lisa Silber, Ross L Cagan

Nat Chem Biol· March 2018

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Non-mammalian models of multiple endocrine neoplasia type 2.
Tirtha K Das, Ross L Cagan

Endocr Relat Cancer· February 2018

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Multi-targeting Drug Community Challenge.
Avner Schlessinger, Ruben Abagyan, Heather A Carlson, Kristen K Dang, Justin Guinney, Ross L Cagan

Cell Chem Biol· December 2017

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