Publications by authors named "Roy Ehling"

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Synthetic coevolution reveals adaptive mutational trajectories of neutralizing antibodies and SARS-CoV-2.
Roy A Ehling, Mason Minot, Max D Overath, Daniel J Sheward, Jiami Han

Cell Syst· September 2025

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Persistent virus-specific and clonally expanded antibody-secreting cells respond to induced self-antigen in the CNS.
Andreas Agrafiotis, Raphael Dizerens, Ilena Vincenti, Ingrid Wagner, Raphael Kuhn, Roy Ehling

Acta Neuropathol· March 2023

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Generation of a single-cell B cell atlas of antibody repertoires and transcriptomes to identify signatures associated with antigen specificity.
Andreas Agrafiotis, Daniel Neumeier, Kai-Lin Hong, Tasnia Chowdhury, Roy Ehling

iScience· March 2023

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Omicron sublineage BA.2.75.2 exhibits extensive escape from neutralising antibodies.
Daniel J Sheward, Changil Kim, Julian Fischbach, Kenta Sato, Sandra Muschiol, Roy A Ehling

Lancet Infect Dis· November 2022

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Evasion of neutralising antibodies by omicron sublineage BA.2.75.
Daniel J Sheward, Changil Kim, Julian Fischbach, Sandra Muschiol, Roy A Ehling

Lancet Infect Dis· October 2022

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Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain.
Joseph M Taft, Cédric R Weber, Beichen Gao, Roy A Ehling, Jiami Han

Cell· October 2022

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Single-cell immune repertoire sequencing of B and T cells in murine models of infection and autoimmunity.
Danielle Shlesinger, Kai-Lin Hong, Ghazal Shammas, Nicolas Page, Ioana Sandu, Roy Ehling

Genes Immun· September 2022

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Neutralisation sensitivity of the SARS-CoV-2 omicron (B.1.1.529) variant: a cross-sectional study.
Daniel J Sheward, Changil Kim, Roy A Ehling, Alec Pankow, Xaquin Castro Dopico

Lancet Infect Dis· June 2022

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Phenotypic determinism and stochasticity in antibody repertoires of clonally expanded plasma cells.
Daniel Neumeier, Alexander Yermanos, Andreas Agrafiotis, Lucia Csepregi, Tasnia Chowdhury, Roy A Ehling

Proc Natl Acad Sci U S A· May 2022

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DeepSARS: simultaneous diagnostic detection and genomic surveillance of SARS-CoV-2.
Alexander Yermanos, Kai-Lin Hong, Andreas Agrafiotis, Jiami Han, Sarah Nadeau, Roy Ehling

BMC Genomics· April 2022

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Profiling the specificity of clonally expanded plasma cells during chronic viral infection by single-cell analysis.
Daniel Neumeier, Alessandro Pedrioli, Alessandro Genovese, Ioana Sandu, Roy Ehling

Eur J Immunol· February 2022

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SARS-CoV-2 reactive and neutralizing antibodies discovered by single-cell sequencing of plasma cells and mammalian display.
Roy A Ehling, Cédric R Weber, Derek M Mason, Simon Friedensohn, Bastian Wagner

Cell Rep· January 2022

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A Single-Cell Atlas of Lymphocyte Adaptive Immune Repertoires and Transcriptomes Reveals Age-Related Differences in Convalescent COVID-19 Patients.
Florian Bieberich, Rodrigo Vazquez-Lombardi, Alexander Yermanos, Roy A Ehling, Derek M Mason

Front Immunol· August 2021

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Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning.
Derek M Mason, Simon Friedensohn, Cédric R Weber, Christian Jordi, Bastian Wagner, Roy A Ehling

Nat Biomed Eng· June 2021

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Molecular Design, Optimization, and Genomic Integration of Chimeric B Cell Receptors in Murine B Cells.
Theresa Pesch, Lucia Bonati, William Kelton, Cristina Parola, Roy A Ehling

Front Immunol· November 2020

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Immune Literacy: Reading, Writing, and Editing Adaptive Immunity.
Lucia Csepregi, Roy A Ehling, Bastian Wagner, Sai T Reddy

iScience· September 2020

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High Efficiency Gene Correction in Hematopoietic Cells by Donor-Template-Free CRISPR/Cas9 Genome Editing.
Duran Sürün, Joachim Schwäble, Ana Tomasovic, Roy Ehling, Stefan Stein

Mol Ther Nucleic Acids· March 2018

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