Publications by authors named "Rozalia Dodean"

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Optimization of Prodiginines as Single-Dose Curative Antimalarials.
Amrendra Kumar, Yuexin Li, Xiaowei Zhang, Mahesh Gaddam, Diana Caridha, Rozalia A Dodean

J Med Chem· November 2025

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Identifying antimalarials that disrupt malaria parasite transmission when fed to the mosquito.
Sarah N Farrell, Anton Cozijnsen, Vanessa Mollard, Papireddy Kancharla, Rozalia A Dodean

Int J Parasitol· September 2025

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Acridone Prodrugs with Enhanced Dual-Stage Antimalarial Efficacy.
Rozalia A Dodean, Yuexin Li, Xiaowei Zhang, Amrendra Kumar, Sovitj Pou

ACS Med Chem Lett· July 2025

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Optimization of Tambjamines Active against Multiple Stages of Malaria Parasites.
Amrendra Kumar, Yuexin Li, Xiaowei Zhang, Xiannu Jin, William E Dennis, Rozalia A Dodean

J Med Chem· June 2025

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Potent Acridone Antimalarial against All Three Life Stages of .
Papireddy Kancharla, Rozalia A Dodean, Yuexin Li, Xiaowei Zhang, Sean Kelly

Res Sq· June 2025

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Development of Next-Generation Antimalarial Acridones with Radical Cure Potential.
Rozalia A Dodean, Yuexin Li, Xiaowei Zhang, Diana Caridha, Michael S Madejczyk

J Med Chem· April 2025

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Tambjamines as Fast-Acting Multistage Antimalarials.
Amrendra Kumar, Yuexin Li, Rozalia A Dodean, Alison Roth, Diana Caridha

ACS Infect Dis· December 2024

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Optimization of B-Ring-Functionalized Antimalarial Tambjamines and Prodiginines.
Amrendra Kumar, Sivanna Chithanna, Yuexin Li, Xiaowei Zhang, Rozalia A Dodean

J Med Chem· November 2024

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Long-acting intramuscular injections of ELQ-331, an antimalarial agent.
Dipu Karunakaran, Shravan K Mutyam, Melody Fu, Jiaming Chen, Kim Hue Nicky Pham, Rozalia A Dodean

Eur J Pharm Sci· July 2024

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3-Position Biaryl Endochin-like Quinolones with Enhanced Antimalarial Performance.
Sovitj Pou, Rolf W Winter, Rozalia A Dodean, Katherine Liebman, Yuexin Li

ACS Infect Dis· July 2024

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Discovery and Optimization of Tambjamines as a Novel Class of Antileishmanial Agents.
Papireddy Kancharla, Diana Ortiz, Corinne M Fargo, Xiaowei Zhang, Yuexin Li, Rozalia A Dodean

J Med Chem· May 2024

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Babesia duncani as a Model Organism to Study the Development, Virulence, and Drug Susceptibility of Intraerythrocytic Parasites In Vitro and In Vivo.
Anasuya C Pal, Isaline Renard, Pallavi Singh, Pratap Vydyam, Joy E Chiu, Rozalia Dodean

J Infect Dis· September 2022

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Effective Therapy Targeting Cytochrome Prevents Erythrocytic Development and Protects from Lethal Infection.
Joy E Chiu, Isaline Renard, Anasuya C Pal, Pallavi Singh, Pratap Vydyam, Rozalia Dodean

Antimicrob Agents Chemother· August 2021

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A New Scalable Synthesis of ELQ-300, ELQ-316, and other Antiparasitic Quinolones.
Sovitj Pou, Rozalia A Dodean, Lisa Frueh, Katherine M Liebman, Rory T Gallagher

Org Process Res Dev· August 2021

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Acridones Are Highly Potent Inhibitors of Tachyzoites.
P Holland Alday, Erin V McConnell, Jan M Boitz Zarella, Rozalia A Dodean, Papireddy Kancharla

ACS Infect Dis· July 2021

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Total Synthesis and Antimalarial Activity of 2-(-Hydroxybenzyl)-prodigiosins, Isoheptylprodigiosin, and Geometric Isomers of Tambjamine MYP1 Isolated from Marine Bacteria.
Papireddy Kancharla, Yuexin Li, Monish Yeluguri, Rozalia A Dodean, Kevin A Reynolds

J Med Chem· June 2021

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Endochin-like quinolone-300 and ELQ-316 inhibit Babesia bovis, B. bigemina, B. caballi and Theileria equi.
Marta G Silva, Reginaldo G Bastos, J Stone Doggett, Michael K Riscoe, Sovitj Pou, Rozalia A Dodean

Parasit Vectors· December 2020

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Orally Bioavailable Endochin-Like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts.
J Stone Doggett, Tracey Schultz, Alyssa J Miller, Igor Bruzual, Sovitj Pou, Rozalia Dodean

Antimicrob Agents Chemother· August 2020

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Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials.
Papireddy Kancharla, Rozalia A Dodean, Yuexin Li, Sovitj Pou, Brandon Pybus

J Med Chem· June 2020

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Boron Trifluoride Etherate Promoted Microwave-Assisted Synthesis of Antimalarial Acridones.
Papireddy Kancharla, Rozalia A Dodean, Yuexin Li, Jane X Kelly

RSC Adv· December 2019

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ELQ-331 as a prototype for extremely durable chemoprotection against malaria.
Martin J Smilkstein, Sovitj Pou, Alina Krollenbrock, Lisa A Bleyle, Rozalia A Dodean

Malar J· August 2019

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Discovery and Structural Optimization of Acridones as Broad-Spectrum Antimalarials.
Rozalia A Dodean, Papireddy Kancharla, Yuexin Li, Victor Melendez, Lisa Read

J Med Chem· April 2019

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Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis.
Erin V McConnell, Igor Bruzual, Sovitj Pou, Rolf Winter, Rozalia A Dodean

ACS Infect Dis· November 2018

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Diphenylether-Modified 1,2-Diamines with Improved Drug Properties for Development against Mycobacterium tuberculosis.
Marie H Foss, Sovitj Pou, Patrick M Davidson, Jennifer L Dunaj, Rolf W Winter, Rozalia A Dodean

ACS Infect Dis· July 2016

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Discovery of dual function acridones as a new antimalarial chemotype.
Jane X Kelly, Martin J Smilkstein, Reto Brun, Sergio Wittlin, Roland A Cooper, Rozalia A Dodean

Nature· May 2009

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