Publications by authors named "Ruben Steigerwald"

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Mechanism of conductance control and neurosteroid binding in NMDA receptors.
Hyunook Kang, Ruben Steigerwald, Elijah Z Ullman, Max Epstein, Srinu Paladugu

Nature· December 2025

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On the mechanism of calcium permeability and magnesium block in NMDA receptors - a central molecular paradigm in neuroplasticity.
Ruben Steigerwald, Max Epstein, Tsung-Han Chou, Hiro Furukawa

bioRxiv· November 2025

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A novel fluorescent labeling compound for GluN2A containing -methyl-d-aspartate receptors identified by autodisplay-based screening.
Alexander Dombovski, Ruben Steigerwald, Nadine Ritter, Paul Disse, Gunnar Goerges

J Pharm Anal· July 2024

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Chemical, pharmacodynamic and pharmacokinetic characterization of the GluN2B receptor antagonist 3-(4-phenylbutyl)-2,3,4,5-tetrahydro-1-3-benzazepine-1,7-diol - starting point for PET tracer development.
Marvin Korff, Ruben Steigerwald, Elena Bechthold, Dirk Schepmann, Julian A Schreiber

Biol Chem· March 2023

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ADME characterization of a very potent 3-acylamino-2-aminopropionic acid-derived GluN2C-NMDA receptor agonist and its ester prodrugs.
Elena Bechthold, Lucie Grey, Emil Diamant, Judith Schmidt, Ruben Steigerwald

Biol Chem· March 2023

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GluN2A-Selective NMDA Receptor Antagonists: Mimicking the U-Shaped Bioactive Conformation of TCN-201 by a [2.2]Paracyclophane System.
Ruben Steigerwald, Tsung-Han Chou, Hiro Furukawa, Bernhard Wünsch

ChemMedChem· November 2022

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[2.2]Paracyclophane-Based TCN-201 Analogs as GluN2A-Selective NMDA Receptor Antagonists.
Remya Rajan, Dirk Schepmann, Ruben Steigerwald, Julian A Schreiber, Ehab El-Awaad

ChemMedChem· October 2021

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