Publications by authors named "Ruby Cai"

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GS-9822, a preclinical LEDGIN candidate, displays a block-and-lock phenotype in cell culture.
Anne Bruggemans, Gerlinde Vansant, Mini Balakrishnan, Michael L Mitchell, Ruby Cai

Antimicrob Agents Chemother· May 2023

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Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle.
Richard L Mackman, Victoria A Steadman, David K Dean, Petr Jansa, Karine G Poullennec, Ruby Cai

J Med Chem· November 2018

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Highly potent HCV NS4B inhibitors with activity against multiple genotypes.
Barton Phillips, Ruby Cai, William Delaney, Zhimin Du, Mingzhe Ji

J Med Chem· March 2014

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Discovery of GS-9451: an acid inhibitor of the hepatitis C virus NS3/4A protease.
X Christopher Sheng, Todd Appleby, Thomas Butler, Ruby Cai, Xiaowu Chen

Bioorg Med Chem Lett· April 2012

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Discovery of GS-9256: a novel phosphinic acid derived inhibitor of the hepatitis C virus NS3/4A protease with potent clinical activity.
X Christopher Sheng, Anthony Casarez, Ruby Cai, Michael O Clarke, Xiaowu Chen

Bioorg Med Chem Lett· February 2012

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Tricyclic HIV integrase inhibitors: potent and orally bioavailable C5-aza analogs.
Haolun Jin, Matthew Wright, Richard Pastor, Michael Mish, Sammy Metobo, Ruby Cai

Bioorg Med Chem Lett· February 2008

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Effect of substitution on novel tricyclic HIV-1 integrase inhibitors.
Maria Fardis, Haolun Jin, Salman Jabri, Ruby Z Cai, Michael Mish

Bioorg Med Chem Lett· August 2006

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Design, synthesis, and SAR studies of novel and highly active tri-cyclic HIV integrase inhibitors.
Haolun Jin, Ruby Z Cai, Laura Schacherer, Salman Jabri, Manuel Tsiang

Bioorg Med Chem Lett· August 2006

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Small molecules VP-14637 and JNJ-2408068 inhibit respiratory syncytial virus fusion by similar mechanisms.
Janet L Douglas, Marites L Panis, Edmund Ho, Kuei-Ying Lin, Steve H Krawczyk, Ruby Cai

Antimicrob Agents Chemother· June 2005

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Inhibition of respiratory syncytial virus fusion by the small molecule VP-14637 via specific interactions with F protein.
Janet L Douglas, Marites L Panis, Edmund Ho, Kuei-Ying Lin, Steve H Krawczyk, Ruby Cai

J Virol· May 2003

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