Publications by authors named "Mini Balakrishnan"

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GS-9822, a preclinical LEDGIN candidate, displays a block-and-lock phenotype in cell culture.
Anne Bruggemans, Gerlinde Vansant, Mini Balakrishnan, Michael L Mitchell, Ruby Cai

Antimicrob Agents Chemother· May 2023

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Evaluation of Broadly Neutralizing Antibody Sensitivity by Genotyping and Phenotyping for Qualifying Participants to HIV Clinical Trials.
Brian Moldt, Aiyappa Parvangada, Ross Martin, Craig Pace, Mini Balakrishnan

J Acquir Immune Defic Syndr· September 2021

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Author Correction: A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19.
Xuping Xie, Antonio E Muruato, Xianwen Zhang, Kumari G Lokugamage, Camila R Fontes-Garfias, Mini Balakrishnan

Nat Commun· June 2021

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A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19.
Xuping Xie, Antonio E Muruato, Xianwen Zhang, Kumari G Lokugamage, Camila R Fontes-Garfias, Mini Balakrishnan

Nat Commun· October 2020

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A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19.
Xuping Xie, Antonio E Muruato, Xianwen Zhang, Kumari G Lokugamage, Camila R Fontes-Garfias, Mini Balakrishnan

bioRxiv· June 2020

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Targeting HIV Reservoir in Infected CD4 T Cells by Dual-Affinity Re-targeting Molecules (DARTs) that Bind HIV Envelope and Recruit Cytotoxic T Cells.
Derek D Sloan, Chia-Ying Kao Lam, Alivelu Irrinki, Liqin Liu, Angela Tsai, Mini Balakrishnan

PLoS Pathog· April 2016

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Non-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cells.
Mini Balakrishnan, Stephen R Yant, Luong Tsai, Christopher O'Sullivan, Rujuta A Bam

PLoS One· June 2014

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Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing.
Datsen George Wei, Vicki Chiang, Elizabeth Fyne, Mini Balakrishnan, Tiffany Barnes

PLoS Pathog· April 2014

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Structural and binding analysis of pyrimidinol carboxylic acid and N-hydroxy quinazolinedione HIV-1 RNase H inhibitors.
Eric B Lansdon, Qi Liu, Stephanie A Leavitt, Mini Balakrishnan, Jason K Perry

Antimicrob Agents Chemother· June 2011

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A recombination hot spot in HIV-1 contains guanosine runs that can form a G-quartet structure and promote strand transfer in vitro.
Wen Shen, Lu Gao, Mini Balakrishnan, Robert A Bambara

J Biol Chem· December 2009

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RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information.
Thorsten A Kirschberg, Mini Balakrishnan, Neil H Squires, Tiffany Barnes, Katherine M Brendza

J Med Chem· October 2009

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A succession of mechanisms stimulate efficient reconstituted HIV-1 minus strand strong stop DNA transfer.
Min Song, Mini Balakrishnan, Robert J Gorelick, Robert A Bambara

Biochemistry· March 2009

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Apparent defects in processive DNA synthesis, strand transfer, and primer elongation of Met-184 mutants of HIV-1 reverse transcriptase derive solely from a dNTP utilization defect.
Lu Gao, Mark Nils Hanson, Mini Balakrishnan, Paul L Boyer, Bernard P Roques

J Biol Chem· April 2008

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Triazole derivatives as non-nucleoside inhibitors of HIV-1 reverse transcriptase--structure-activity relationships and crystallographic analysis.
Thorsten A Kirschberg, Mini Balakrishnan, Wei Huang, Rebecca Hluhanich, Nilima Kutty

Bioorg Med Chem Lett· February 2008

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Insights into the multiple roles of pausing in HIV-1 reverse transcriptase-promoted strand transfers.
Lu Gao, Mini Balakrishnan, Bernard P Roques, Robert A Bambara

J Biol Chem· March 2007

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Evidence that creation of invasion sites determines the rate of strand transfer mediated by HIV-1 reverse transcriptase.
Mark Nils Hanson, Mini Balakrishnan, Bernard P Roques, Robert A Bambara

J Mol Biol· November 2006

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Reduced dNTP interaction of human immunodeficiency virus type 1 reverse transcriptase promotes strand transfer.
Darwin J Operario, Mini Balakrishnan, Robert A Bambara, Baek Kim

J Biol Chem· October 2006

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Stimulation of HIV-1 minus strand strong stop DNA transfer by genomic sequences 3' of the primer binding site.
Min Song, Mini Balakrishnan, Yan Chen, Bernard P Roques, Robert A Bambara

J Biol Chem· August 2006

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Evidence that HIV-1 reverse transcriptase employs the DNA 3' end-directed primary/secondary RNase H cleavage mechanism during synthesis and strand transfer.
Vandana Purohit, Mini Balakrishnan, Baek Kim, Robert A Bambara

J Biol Chem· December 2005

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Effects of donor and acceptor RNA structures on the mechanism of strand transfer by HIV-1 reverse transcriptase.
Mark Nils Hanson, Mini Balakrishnan, Bernard P Roques, Robert A Bambara

J Mol Biol· November 2005

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Acceptor RNA cleavage profile supports an invasion mechanism for HIV-1 minus strand transfer.
Yan Chen, Mini Balakrishnan, Bernard P Roques, Robert A Bambara

J Biol Chem· April 2005

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Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase.
Tracy L Diamond, Mikhail Roshal, Varuni K Jamburuthugoda, Holly M Reynolds, Aaron R Merriam, Mini Balakrishnan

J Biol Chem· December 2004

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Identification of a preferred region for recombination and mutation in HIV-1 gag.
Carrie Dykes, Mini Balakrishnan, Vicente Planelles, Yonghong Zhu, Robert A Bambara

Virology· September 2004

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Steps of the acceptor invasion mechanism for HIV-1 minus strand strong stop transfer.
Yan Chen, Mini Balakrishnan, Bernard P Roques, Robert A Bambara

J Biol Chem· October 2003

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Role of the Reverse Transcriptase, Nucleocapsid Protein, and Template Structure in the Two-step Transfer Mechanism in Retroviral Recombination.
Ricardo H Roda, Mini Balakrishnan, Mark N Hanson, Birgitta M Wohrl, Stuart F J Le Grice

J Biol Chem· August 2003

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