Publications by authors named "Brian Moldt"

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HIV-1 envelope diversity and sensitivity to broadly neutralizing antibodies across stages of acute HIV-1 infection.
Laurie A VanderVeen, Lisa Selzer, Brian Moldt, Aiyappa Parvangada, Jiani Li

AIDS· March 2024

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HIV envelope antibodies and TLR7 agonist partially prevent viral rebound in chronically SHIV-infected monkeys.
Brian Moldt, Abishek Chandrashekar, Erica N Borducchi, Joseph P Nkolola, Heather Stephenson

PLoS Pathog· April 2022

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Evaluation of HIV-1 reservoir size and broadly neutralizing antibody susceptibility in acute antiretroviral therapy-treated individuals.
Brian Moldt, Huldrych F Günthard, Kimberly A Workowski, Susan J Little, Joseph J Eron

AIDS· February 2022

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Evaluation of Broadly Neutralizing Antibody Sensitivity by Genotyping and Phenotyping for Qualifying Participants to HIV Clinical Trials.
Brian Moldt, Aiyappa Parvangada, Ross Martin, Craig Pace, Mini Balakrishnan

J Acquir Immune Defic Syndr· September 2021

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The TLR7 agonist vesatolimod induced a modest delay in viral rebound in HIV controllers after cessation of antiretroviral therapy.
Devi SenGupta, Cynthia Brinson, Edwin DeJesus, Anthony Mills, Peter Shalit, Brian Moldt

Sci Transl Med· June 2021

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Highly Attenuated Infection With a Vpr-Deleted Molecular Clone of Human Immunodeficiency Virus-1.
Ayub Ali, Hwee L Ng, Joel N Blankson, Dennis R Burton, Robert W Buckheit, Brian Moldt

J Infect Dis· September 2018

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Prevalence and Significance of Substitutions in the Fusion Protein of Respiratory Syncytial Virus Resulting in Neutralization Escape From Antibody MEDI8897.
Qing Zhu, Bin Lu, Patrick McTamney, Susan Palaszynski, Seme Diallo, Brian Moldt

J Infect Dis· July 2018

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A highly potent extended half-life antibody as a potential RSV vaccine surrogate for all infants.
Qing Zhu, Jason S McLellan, Nicole L Kallewaard, Nancy D Ulbrandt, Susan Palaszynski, Brian Moldt

Sci Transl Med· May 2017

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Protection of Humanized Mice From Repeated Intravaginal HIV Challenge by Passive Immunization: A Model for Studying the Efficacy of Neutralizing Antibodies In Vivo.
Maud Deruaz, Brian Moldt, Khoa M Le, Karen A Power, Vladimir D Vrbanac

J Infect Dis· August 2016

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Comparison of Antibody-Dependent Cell-Mediated Cytotoxicity and Virus Neutralization by HIV-1 Env-Specific Monoclonal Antibodies.
Benjamin von Bredow, Juan F Arias, Lisa N Heyer, Brian Moldt, Khoa Le

J Virol· July 2016

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Neutralizing antibody affords comparable protection against vaginal and rectal simian/human immunodeficiency virus challenge in macaques.
Brian Moldt, Khoa M Le, Diane G Carnathan, James B Whitney, Niccole Schultz

AIDS· June 2016

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HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers.
Rogier W Sanders, Marit J van Gils, Ronald Derking, Devin Sok, Thomas J Ketas, Brian Moldt

Science· July 2015

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Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques.
Masashi Shingai, Olivia K Donau, Ronald J Plishka, Alicia Buckler-White, John R Mascola, Brian Moldt

J Exp Med· September 2014

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Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins.
Gregory Q Del Prete, Braiden Eilers, Brian Moldt, Brandon F Keele, Jacob D Estes

Cell Host Microbe· September 2014

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The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells.
Sandeep Gupta, Johannes S Gach, Juan C Becerra, Tran B Phan, Jeffrey Pudney, Brian Moldt

PLoS Pathog· June 2014

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HIV-1 Vpu antagonism of tetherin inhibits antibody-dependent cellular cytotoxic responses by natural killer cells.
Raymond A Alvarez, Rebecca E Hamlin, Anthony Monroe, Brian Moldt, Mathew T Hotta

J Virol· June 2014

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Tetherin antagonism by Vpu protects HIV-infected cells from antibody-dependent cell-mediated cytotoxicity.
Juan F Arias, Lisa N Heyer, Benjamin von Bredow, Kim L Weisgrau, Brian Moldt

Proc Natl Acad Sci U S A· April 2014

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DNA transposition by protein transduction of the piggyBac transposase from lentiviral Gag precursors.
Yujia Cai, Rasmus O Bak, Louise Bechmann Krogh, Nicklas H Staunstrup, Brian Moldt

Nucleic Acids Res· February 2014

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Prevention of cell death by antibodies selected from intracellular combinatorial libraries.
Jia Xie, Kyungmoo Yea, Hongkai Zhang, Brian Moldt, Linling He

Chem Biol· February 2014

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Simplifying the synthesis of SIgA: combination of dIgA and rhSC using affinity chromatography.
Brian Moldt, Karen Saye-Francisco, Niccole Schultz, Dennis R Burton, Ann J Hessell

Methods· January 2014

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Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys.
Dan H Barouch, James B Whitney, Brian Moldt, Florian Klein, Thiago Y Oliveira

Nature· November 2013

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SnapShot: broadly neutralizing antibodies.
Devin Sok, Brian Moldt, Dennis R Burton

Cell· October 2013

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Protection against high-dose highly pathogenic mucosal SIV challenge at very low serum neutralizing titers of the antibody-like molecule CD4-IgG2.
Pascal Poignard, Brian Moldt, Karla Maloveste, Noëlie Campos, William C Olson

PLoS One· January 2013

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Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant.
Rozh H Al-Mashhadi, Charlotte B Sørensen, Peter M Kragh, Christina Christoffersen, Martin B Mortensen, Brian Moldt

Sci Transl Med· January 2013

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Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo.
Brian Moldt, Eva G Rakasz, Niccole Schultz, Po-Ying Chan-Hui, Kristine Swiderek

Proc Natl Acad Sci U S A· November 2012

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