Publications by authors named "Jacob D Estes"

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Meeting Summary for Keystone Symposia on HIV Cure: Antiretroviral Therapy (ART)-Free Control of HIV Infection in Durban, South Africa, 2025.
Kiho Tanaka, Tatenda Jimmy Blessing Chikowore, Steven G Deeks, Jacob D Estes, Ya-Chi Ho

Pathog Immun· October 2025

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Neuroinflammation associated with proviral DNA persists in the brain of virally suppressed people with HIV.
Sarah J Byrnes, Janna Jamal Eddine, Jingling Zhou, Emily Chalmers, Emma Wanicek, Jacob D Estes

Front Immunol· June 2025

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Editorial: Viral impact on CNS: mechanisms of immune dysfunction and cognitive decline.
Thomas A Angelovich, Sonia Mediouni, Robyn S Klein, Jacob D Estes, Bruce J Brew

Front Immunol· June 2025

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Impact of Dolutegravir Plus Lamivudine as First-line Antiretroviral Treatment on the Human Immunodeficiency Virus Type 1 Reservoir and Inflammatory Markers in Peripheral Blood.
Lucía Bailón, Maria C Puertas, Maria C García-Guerrero, Igor Moraes-Cardoso, Ester Aparicio, Jacob D Estes

J Infect Dis· March 2025

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Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption.
Susan Pereira Ribeiro, Zachary Strongin, Hugo Soudeyns, Felipe Ten-Caten, Khader Ghneim, Jacob D Estes

Nat Immunol· March 2025

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Contribution of intact viral genomes persisting in blood and tissues during ART to plasma viral rebound in SHIV-infected rhesus macaques.
César Trifone, Corentin Richard, Amélie Pagliuzza, Caroline Dufour, Audrée Lemieux, Jacob D Estes

iScience· March 2025

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Rapid systemic spread and minimal immune responses following SIVsab intrarectal transmission in African green monkeys.
Kevin D Raehtz, Cuiling Xu, Claire Deleage, Dongzhu Ma, Benjamin B Policicchio, Jacob D Estes

JCI Insight· December 2024

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Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption.
Susan Pereira Ribeiro, Zachary Strongin, Hugo Soudeyns, Felipe Ten-Caten, Khader Ghneim, Jacob D Estes

Nat Immunol· October 2024

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HIV transcription persists in the brain of virally suppressed people with HIV.
Janna Jamal Eddine, Thomas A Angelovich, Jingling Zhou, Sarah J Byrnes, Carolin Tumpach, Jacob D Estes

PLoS Pathog· August 2024

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Engineered deletions of HIV replicate conditionally to reduce disease in nonhuman primates.
Fathima N Nagoor Pitchai, Elizabeth J Tanner, Neha Khetan, Gustavo Vasen, Clara Levrel, Jacob D Estes

Science· August 2024

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Impact of alemtuzumab-mediated lymphocyte depletion on SIV reservoir establishment and persistence.
Benjamin Varco-Merth, Morgan Chaunzwa, Derick M Duell, Alejandra Marenco, William Goodwin, Jacob D Estes

PLoS Pathog· August 2024

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Regional Analysis of Intact and Defective HIV Proviruses in the Brain of Viremic and Virally Suppressed People with HIV.
Thomas A Angelovich, Catherine R Cochrane, Jingling Zhou, Carolin Tumpach, Sarah J Byrnes, Jacob D Estes

Ann Neurol· October 2023

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Spontaneous HIV expression during suppressive ART is associated with the magnitude and function of HIV-specific CD4 and CD8 T cells.
Mathieu Dubé, Olivier Tastet, Caroline Dufour, Gérémy Sannier, Nathalie Brassard, Jacob D Estes

Cell Host Microbe· September 2023

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Allogeneic immunity clears latent virus following allogeneic stem cell transplantation in SIV-infected ART-suppressed macaques.
Helen L Wu, Kathleen Busman-Sahay, Whitney C Weber, Courtney M Waytashek, Carla D Boyle, Jacob D Estes

Immunity· July 2023

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Correction: Tracking the Luminal Exposure and Lymphatic Drainage Pathways of Intravaginal and Intrarectal Inocula Used in Nonhuman Primate Models of HIV Transmission.
Jeremy Smedley, Baris Turkbey, Marcelino L Bernardo, Gregory Q Del Prete, Jacob D Estes

PLoS One· July 2023

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Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
Elise G Viox, Timothy N Hoang, Amit A Upadhyay, Rayhane Nchioua, Maximilian Hirschenberger, Jacob D Estes

Sci Immunol· July 2023

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Lymph-Node-Based CD3 CD20 Cells Emerge from Membrane Exchange between T Follicular Helper Cells and B Cells and Increase Their Frequency following Simian Immunodeficiency Virus Infection.
Sadia Samer, Ankita Chowdhury, Tomas Raul Wiche Salinas, Perla M Del Rio Estrada, Morgan Reuter, Jacob D Estes

J Virol· June 2023

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Correction: Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques.
Rachele M Bochart, Kathleen Busman-Sahay, Stephen Bondoc, David W Morrow, Alexandra M Ortiz, Jacob D Estes

PLoS Pathog· April 2023

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In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation.
Björn-Erik Ole Jensen, Elena Knops, Leon Cords, Nadine Lübke, Maria Salgado, Jacob D Estes

Nat Med· March 2023

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Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques.
Sarah J Byrnes, Kathleen Busman-Sahay, Thomas A Angelovich, Skyler Younger, Sol Taylor-Brill, Jacob D Estes

PLoS Pathog· March 2023

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Prolonged experimental CD4 T-cell depletion does not cause disease progression in SIV-infected African green monkeys.
Quentin Le Hingrat, Paola Sette, Cuiling Xu, Andrew R Rahmberg, Lilas Tarnus, Jacob D Estes

Nat Commun· February 2023

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Novel Lymphocytic Choriomeningitis Virus Strain Sustains Abundant Exhausted Progenitor CD8 T Cells without Systemic Viremia.
Lalit K Beura, Milcah C Scott, Mark J Pierson, Vineet Joag, Sathi Wijeyesinghe, Jacob D Estes

J Immunol· November 2022

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Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
Timothy N Hoang, Elise G Viox, Amit A Upadhyay, Zachary Strongin, Gregory K Tharp, Jacob D Estes

bioRxiv· October 2022

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An in situ analysis pipeline for initial host-pathogen interactions reveals signatures of human colorectal HIV transmission.
Heeva Baharlou, Nicolas Canete, Erica E Vine, Kevin Hu, Di Yuan, Jacob D Estes

Cell Rep· September 2022

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Non-Human Primate Models of HIV Brain Infection and Cognitive Disorders.
Sarah J Byrnes, Thomas A Angelovich, Kathleen Busman-Sahay, Catherine R Cochrane, Michael Roche, Jacob D Estes

Viruses· September 2022

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