Publications by authors named "Rukmini Kumar"

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An integrated quantitative systems pharmacology virtual population approach for calibration with oncology efficacy endpoints.
Nathan Braniff, Tanvi Joshi, Tyler Cassidy, Michael Trogdon, Rukmini Kumar

CPT Pharmacometrics Syst Pharmacol· February 2025

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Integrating Model-Informed Drug Development With AI: A Synergistic Approach to Accelerating Pharmaceutical Innovation.
Karthik Raman, Rukmini Kumar, Cynthia J Musante, Subha Madhavan

Clin Transl Sci· January 2025

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Multiscale, mechanistic model of Rheumatoid Arthritis to enable decision making in late stage drug development.
Dinesh Bedathuru, Maithreye Rengaswamy, Madhav Channavazzala, Tamara Ray, Prakash Packrisamy, Rukmini Kumar

NPJ Syst Biol Appl· November 2024

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Applying quantitative and systems pharmacology to drug development and beyond: An introduction to clinical pharmacologists.
Mathan Kumar Ramasubbu, Bhairav Paleja, Anand Srinivasann, Rituparna Maiti, Rukmini Kumar

Indian J Pharmacol· July 2024

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Quantitative systems pharmacology model of erythropoiesis to simulate therapies targeting anemia due to chronic kidney disease.
Mrittika Roy, Shaifali Saroha, Uddipan Sarma, Harini Sarathy, Rukmini Kumar

Front Pharmacol· December 2023

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Can a propensity score matching method be applied to assessing efficacy from single-arm proof-of-concept trials in oncology?
Shu-Wen Teng, Yu-Cheng Su, Ravikumar Pallantla, Madhav Channavazzala, Rukmini Kumar

CPT Pharmacometrics Syst Pharmacol· September 2023

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Incorporating lesion-to-lesion heterogeneity into early oncology decision making.
Rukmini Kumar, Timothy Qi, Yanguang Cao, Brian Topp

Front Immunol· June 2023

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Beyond the single average tumor: Understanding IO combinations using a clinical QSP model that incorporates heterogeneity in patient response.
Rukmini Kumar, Kannan Thiagarajan, Lakshmanan Jagannathan, Liming Liu, Kapil Mayawala

CPT Pharmacometrics Syst Pharmacol· July 2021

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In vitro to in vivo extrapolation and species response comparisons for drug-induced liver injury (DILI) using DILIsym™: a mechanistic, mathematical model of DILI.
Brett A Howell, Yuching Yang, Rukmini Kumar, Jeffrey L Woodhead, Alison H Harrill

J Pharmacokinet Pharmacodyn· October 2012

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A mathematical simulation of the inflammatory response to anthrax infection.
Rukmini Kumar, Carson C Chow, John D Bartels, Gilles Clermont, Yoram Vodovotz

Shock· January 2008

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In silico models of acute inflammation in animals.
Yoram Vodovotz, Carson C Chow, John Bartels, Claudio Lagoa, Jose M Prince, Rukmini Kumar

Shock· September 2006

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The acute inflammatory response in diverse shock states.
Carson C Chow, Gilles Clermont, Rukmini Kumar, Claudio Lagoa, Zacharia Tawadrous

Shock· July 2005

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In silico design of clinical trials: a method coming of age.
Gilles Clermont, John Bartels, Rukmini Kumar, Greg Constantine, Yoram Vodovotz

Crit Care Med· October 2004

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The dynamics of acute inflammation.
Rukmini Kumar, Gilles Clermont, Yoram Vodovotz, Carson C Chow

J Theor Biol· September 2004

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